Novel HIV-1 protease inhibitors active against multiple PI-Resistant viral strains: Coadministration with indinavir

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 22, 2003, Pages 4027-4030

  Kevin, Nancy J ^a   Duffy, Joseph L ^a   Kirk, Brian A ^a   Chapman, Kevin T ^a   Schleif, William A ^a   Olsen, David B ^a   Stahlhut, Mark ^a   Rutkowski, Carrie A ^a   Kuo, Lawrence C ^a   Jin, Lixia ^a   Lin, Jiunn H ^a   Emini, Emilio A ^a   Tata, James R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; FURAN DERIVATIVE; INDINAVIR; PROTEINASE; PROTEINASE INHIBITOR; PYRROLE DERIVATIVE; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; DRUG POTENCY; DRUG SOLUBILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; LIPOPHILICITY; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; VIRUS STRAIN;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 10744228175     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.08.049     Document Type: Article

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