DPPIV, seprase, and related serine peptidases in multiple cellular functions

Current Topics in Developmental Biology

Volumn 54, Issue , 2003, Pages 207-232

  Chen, Wen Tien ^a   Kelly, Thomas ^b   Ghersi, Giulio ^c  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; GELATINASE; MEMBRANE PROTEIN; SEPRASE; SERINE PROTEINASE;

ANIMAL; CELL MEMBRANE; ENZYMOLOGY; EUKARYOTIC CELL; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; REVIEW;

ANIMALS; ANTIGENS, CD26; CELL MEMBRANE; EUKARYOTIC CELLS; GELATINASES; HUMANS; MEMBRANE PROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SERINE ENDOPEPTIDASES;

EID: 0642277907     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0070-2153(03)54010-8     Document Type: Review

References (78)

1. C.A Abbott E Baker G.R Sutherland G.W McCaughan Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene Immunogenetics 40 1994 331 338 [published erratum appears in Immunogenetics (1995) 42, 76]
2. C.A Abbott G.W McCaughan M.D Gorrell Two highly conserved glutamic acid residues in the predicted beta propeller domain of dipeptidyl peptidase IV are required for its enzyme activity FEBS Letters 458 1999 278 284
3. C.A Abbott G.W McCaughan M.T Levy W.B Church M.D Gorrell Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted beta propeller domain Eur. J. Biochem. 266 1999 798 810
4. C.A Abbott D.M Yu E Woollatt G.R Sutherland G.W McCaughan M.D Gorrell Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8 Eur. J. Biochem. 267 2000 6140 6150
5. A Aoyama W.-T Chen A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells Proc. Natl. Acad. Sci. USA 87 1990 8296 8300
6. N Ariga E Sato N Ohuchi H Nagura H Ohtani Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast Int. J. Cancer 95 2001 67 72
7. A.J Barrett N.D Rawlings Oligopeptidases, and the emergence of the prolyl oligopeptidase family Biol. Chem. Hoppe Seyler 373 1992 353 360
8. B Bauvois Transmembrane proteases in focus: diversity and redundancy J. Leukoc. Biol. 70 2001 11 17
9. F Bermpohl K Löster W Reutter O Baum Rat dipeptidyl peptidase IV (DPP IV) exhibits endopeptidase activity with specificity for denatured fibrillar collagens FEBS Lett. 428 1998 152 156
10. J Blanco C Nguyen C Callebaut E Jacotot B Krust J.P Mazaleyrat M Wakselman A.G Hovanessian Dipeptidyl-peptidase IV-beta-further characterization and comparison to dipeptidyl-peptidase IV activity of CD26 Eur. J. Biochem. 256 1998 369 378
11. W.-T Chen C.C Lee L Goldstein S Bernier C.H Liu C.Y Lin Y Yeh W.L Monsky T Kelly M Dai S.C Mueller Membrane proteases as potential diagnostic and therapeutic targets for breast malignancy Breast Cancer Res. Treat. 31 1994 217 226
12. H.C Cheng M Abdel-Ghany R.C Elble B.U Pauli Lung endothelial dipeptidyl peptidase IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin J. Biol. Chem. 273 1998 24207 24215
13. H.C Cheng M Abdel-Ghany S Zhang B.U Pauli Is the Fischer 344/CRJ rat a protein-knock-out model for dipeptidyl peptidase IV-mediated lung metastasis of breast cancer Clin. Exp. Metastasis 17 1999 609 615
14. M Chiravuri H Lee S.L Mathieu B.T Huber Homodimerization via a leucine zipper motif is required for enzymatic activity of quiescent cell proline dipeptidase J. Biol. Chem. 275 2000 26994 26999
15. M Chiravuri F Agarraberes S.L Mathieu H Lee B.T Huber Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase J. Immunol. 165 2000 5695 5702
16. E.M Danielsen Dimeric assembly of enterocyte brush border enzymes Biochemistry 33 1994 1599 1605
17. F David L Baricault C Sapin X Gallet D Marguet A Thomas-Soumarmon G Trugnan Reduced cell surface expression of a mutated dipeptidyl peptidase iv (dpp iv/cd26) correlates with the generation of a beta strand in its c-terminal domain Biochem. Biophys. Res. Commun. 222 1996 833 838
18. F David A.M Bernard M Pierres D Marguet Identification of serine 624, aspartic acid 702, and histidine 734 as the catalytic triad residues of mouse dipeptidyl-peptidase IV (CD26) A member of a novel family of nonclassical serine hydrolases J. Biol. Chem. 268 1993 17247 17252
19. I De Meester S Korom J Van Damme S Scharpe CD26, let it cut or cut it down [Review] Immunol. Today 20 1999 367 375
20. C.F Deacon T.E Hughes J.J Holst Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig Diabetes 47 1998 764 769
21. J Dobers S Grams W Reutter H Fan Roles of cysteines in rat dipeptidyl peptidase IV/CD26 in processing and proteolytic activity Eur. J. Biochem. 267 2000 5093 5100
22. R.P Dong K Tachibana M Hegen Y Munakata D Cho S.F Schlossman C Morimoto Determination of adenosine deaminase binding domain on CD26 and its immunoregulatory effect on T cell activation J. Immunol. 159 1997 6070 6076
23. R.P Dong K Tachibana M Hegen S Scharpe D Cho S.F Schlossman C Morimoto Correlation of the epitopes defined by anti-CD26 mAbs and CD26 function Mol. Immunol. 35 1998 13 21
24. J.S Duke-Cohan C Morimoto J.A Rocker S.F Schlossman A novel form of dipeptidylpeptidase IV found in human serum Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26) J. Biol. Chem. 270 1995 14107 14114
25. J.S Duke-Cohan J Gu D.F McLaughlin Y Xu G.J Freeman S.F Schlossman Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions Proc. Natl. Acad. Sci. USA 95 1998 11336 11341
26. C Durinx A.M Lambeir E Bosmans J.B Falmagne R Berghmans A Haemers S Scharpe M.I De Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides Eur. J. Biochem. 267 2000 5608 5613
27. H Fan W.M Meng C Kilian S Grams W Reutter Domain-specific N-glycosylation of the membrane glycoprotein dipeptidylpeptidase IV (CD26) influences its subcellular trafficking, biological stability, enzyme activity and protein folding Eur. J. Biochem. 246 1997 243 251
28. O Fodstad S Aamdal M McMenamin J.M Nesland A Pihl A new experimental metastasis model in athymic nude mice, the human malignant melanoma LOX Int. J. Cancer 41 1988 442 449
29. V Fulop Z Bocskei L Polgar Prolyl oligopeptidase: an unusual beta-propeller domain regulates proteolysis Cell 94 1998 161 170
30. P Garin-Chesa L.J Old W.J Rettig Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers Proc. Natl. Acad. Sci. USA 87 1990 7235 7239
31. G Ghersi W.-T Chen E.W Lee Z Zukowska Critical role of dipeptidyl peptidase IV in neuropeptide Y-mediated endothelial cell migration in response to wounding Peptides 22 2001 453 458
32. L.A Goldstein W.-T Chen Identification of an alternatively spliced seprase mRNA that encodes a novel intracellular isoform J. Biol. Chem. 275 2000 2554 2559
33. L.A Goldstein G Ghersi M.L Piñeiro-Sánchez M Salamone Y.Y Yeh D Flessate W.-T Chen Molecular cloning of seprase: A serine integral membrane protease from human melanoma Biochim. Biophys. Acta 1361 1997 11 19
34. F.J Goossens J.G Wauters G.C Vanhoof P.J Bossuyt K.A Schatteman K Loens S.L Scharpe Subregional mapping of the human lymphocyte prolyl oligopeptidase gene (PREP) to human chromosome 6q22 Cytogenet. Cell Genet. 74 1996 99 101
35. M Hegen J Kameoka R.P Dong S.F Schlossman C Morimoto Cross-linking of CD26 by antibody induces tyrosine phosphorylation and activation of mitogen-activated protein kinase Immunology 90 1997 257 264
36. P.J Hensbergen E.M Raaij-Helmer R Dijkman R.C van der Schors G Werner-Felmayer D.M Boorsma R.J Scheper R Willemze C.P Tensen Processing of natural and recombinant CXCR3-targeting chemokines and implications for biological activity Eur. J. Biochem. 268 2001 4992 4999
37. K Hirai T Kotani Y Aratake S Ohtaki K Kuma Dipeptidyl peptidase IV (DPP IV/CD26) staining predicts distant metastasis of “benign” thyroid tumor [letter] Pathol. Int. 49 1999 264 265
38. V.K Hopsu-Havu G.G Glenner A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamide Histochemie 7 1966 197 201
39. H Ikushima Y Munakata T Ishii S Iwata M Terashima H Tanaka S.F Schlossman C Morimoto Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation Proc. Natl. Acad. Sci. USA 97 2000 8439 8444
40. T Ishii K Ohnuma A Murakami N Takasawa S Kobayashi N.H Dang S.F Schlossman C Morimoto CD26-mediated signaling for T cell activation occurs in lipid rafts through its association with CD45RO Proc. Natl. Acad. Sci. USA 98 2001 12138 12143
41. R.C Johnson D Zhu H.G Augustin-Voss B.U Pauli Lung endothelial dipeptidyl peptidase IV is an adhesion molecule for lung-metastatic rat breast and prostate carcinoma cells J. Cell Biol. 121 1993 1423 1432
42. T Kelly Evaluation of seprase activity Clin. Exp. Metastasis 17 1999 57 62
43. T Kelly S Kechelava T.L Rozypal K.W West S Korourian Seprase, a membrane-bound protease, is overexpressed by invasive ductal carcinoma cells of human breast cancers Mod. Pathol. 11 1998 855 863
44. A.M Lambeir P Proost C Durinx G Bal K Senten K Augustyns S Scharpe J Van Damme I De Meester Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family J. Biol. Chem. 276 2001 29839 29845
45. M.T Levy G.W McCaughan C.A Abbott J.E Park A.M Cunningham E Muller W.J Rettig M.D Gorrell Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis Hepatology 29 1999 1768 1778
46. K Loster K Zeilinger D Schuppan W Reutter The cysteine-rich region of dipeptidyl peptidase IV (CD 26) is the collagen-binding site Biochem. Biophys. Res. Commun. 217 1995 341 348
47. D Marguet L Baggio T Kobayashi A.M Bernard M Pierres P.F Nielsen U Ribel T Watanabe D.J Drucker N Wagtmann Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26 Proc. Natl. Acad. Sci. USA 97 2000 6874 6879
48. J.M Mason H.P Xu S.K Rao A Leask M Barcia J Shan R Stephenson S Tabibzadeh Lefty contributes to the remodeling of extracellular matrix by inhibition of connective tissue growth factor and collagen mRNA expression and increased proteolytic activity in a fibrosarcoma model J. Biol. Chem. 277 2001 407 415
49. F.J Medrano J Alonso J.L Garcia A Romero W Bode F.X Gomis-Ruth Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family EMBO J. 17 1998 1 9
50. R Mentlein Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides Regul. Pept. 85 1999 9 24
51. R Mentlein G Struckhoff Purification of two dipeptidyl aminopeptidases II from rat brain and their action on proline-containing neuropeptides J. Neurochem. 52 1989 1284 1293
52. W.L Monsky C.-Y Lin A Aoyama T Kelly S.C Mueller S.K Akiyama W.-T Chen A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells Cancer Res. 54 1994 5702 5710
53. C Morimoto S.F Schlossman The structure and function of CD26 in the T-cell immune response Immunol. Rev. 161 1998 55 70 [Review]
54. H Nakahara L Howard E.W Thompson H Sato M Seiki Y Yeh W.-T Chen Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion Proc. Natl. Acad. Sci. USA 94 1997 7959 7964
55. J Niedermeyer P Garin-Chesa M Kriz F Hilberg E Mueller U Bamberger W.J Rettig A Schnapp Expression of the fibroblast activation protein during mouse embryo development Int. J. Dev. Biol. 45 2001 445 447
56. J Niedermeyer M Kriz F Hilberg P Garin-Chesa U Bamberger M.C Lenter J Park B Viertel H Puschner M Mauz W.J Rettig A Schnapp Targeted disruption of mouse fibroblast activation protein Mol. Cell. Biol. 20 2000 1089 1094
57. J Niedermeyer B Enenkel J.E Park M Lenter W.J Rettig K Damm A Schnapp Mouse fibroblast-activation protein-conserved Fap gene organization and biochemical function as a serine protease Eur. J. Biochem. 254 1998 650 654
58. S Ogata Y Misumi Y Ikehara Primary structure of rat liver dipeptidyl peptidase IV deduced from its cDNA and identification of the NH2 -terminal signal sequence as the membrane-anchoring domain J. Biol. Chem. 264 1989 3596 3601
59. M.N Pangalos J.M Neefs M Somers P Verhasselt M Bekkers L van der Helm E Fraiponts D Ashton R.D Gordon Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity J. Biol. Chem. 274 1999 8470 8483
60. J.E Park M.C Lenter R.N Zimmermann P Garin-Chesa L.J Old W.J Rettig Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts J. Biol. Chem. 274 1999 36505 36512
61. M.L Pineiro-Sanchez L.A Goldstein J Dodt L Howard Y Yeh H Tran W.S Argraves W.-T Chen Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease J. Biol. Chem. 272 1997 7595 7601 [Correction (1998). J. Biol. Chem. 273, 13366]
62. P Proost I De Meester D Schols S Struyf A.M Lambeir A Wuyts G Opdenakker E De Clercq S Scharpe J Van Damme Amino-terminal truncation of chemokines by CD26/dipeptidylpeptidase IV-Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection J. Biol. Chem. 273 1998 7222 7227
63. P Proost E Schutyser P Menten S Struyf A Wuyts G Opdenakker M Detheux M Parmentier C Durinx A.M Lambeir J Neyts S Liekens P.C Maudgal A Billiau J Van Damme Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties Blood 98 2001 3554 3561
64. D Rajotte E Ruoslahti Membrane dipeptidase is the receptor for a lung-targeting peptide identified by in vivo phage display J. Biol. Chem. 274 1999 11593 11598
65. W.J Rettig P Garin-Chesa H.R Beresford H.F Oettgen M.R Melamed L.J Old Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells Proc. Natl. Acad. Sci. USA 85 1988 3110 3114
66. W.J Rettig P Garin-Chesa J.H Healey S.L Su H.L Ozer M Schwab A.P Albino L.J Old Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroectodermal origin Cancer Res. 53 1993 3327 3335
67. W.J Rettig S.L Su S.R Fortunato M.J Scanlan B.K Raj P Garin-Chesa J.H Healey L.J Old Fibroblast activation protein: purification, epitope mapping and induction by growth factors Int. J. Cancer 58 1994 385 392
68. E Ruoslahti D Rajotte An address system in the vasculature of normal tissues and tumors Annu. Rev. Immunol. 18 2000 813 827
69. H Sato T Takino Y Okada J Cao A Shinagawa E Yamamoto M Seiki A matrix metalloproteinase expressed on the surface of invasive tumour cells Nature 370 1994 61 65
70. M.J Scanlan B.K Raj B Calvo P Garin-Chesa M.P Sanz-Moncasi J.H Healey L.J Old W.J Rettig Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers Proc. Natl. Acad. Sci. USA 91 1994 5657 5661
71. F Tan P.W Morris R.A Skidgel E.G Erdos Sequencing and cloning of human prolylcarboxypeptidase (angiotensinase C) Similarity to both serine carboxypeptidase and prolylendopeptidase families J. Biol. Chem. 268 1993 16631 16638 [published erratum appears in J. Biol. Chem. (1993). 268, 26032]
72. W Tang T.M Gunn D.F McLaughlin G.S Barsh S.F Schlossman J.S Duke-Cohan Secreted and membrane attractin result from alternative splicing of the human ATRN gene Proc. Natl. Acad. Sci. USA 97 2000 6025 6030
73. T Uekita Y Itoh I Yana H Ohno M Seiki Cytoplasmic tail-dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity J. Cell Biol. 155 2001 1345 1356
74. R Underwood M Chiravuri H Lee T Schmitz A.K Kabcenell K Yardley B.T Huber Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase J. Biol. Chem. 274 1999 34053 34058
75. U.V Wesley A.P Albino S Tiwari A.N Houghton A role for dipeptidyl peptidase IV in suppressing the malignant phenotype of melanocytic cells J. Exp. Med. 190 1999 311 322
76. N Yokotani K Doi R.J Wenthold K Wada Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7 Hum. Mol. Genet. 2 1993 1037 1039
77. S Zucker J Cao W.-T Chen Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment Oncogene 19 2000 6642 6650
78. Z Zukowska-Grojec P Karwatowska W Rose J Rone S Movafagh H Ji Y Yeh W.-T Chen H.K Kleinman E Grouzmann D.S Grant Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium Circ. Res. 83 1998 187 195