Effects of endotoxic shock on right ventricular systolic function and mechanical efficiency

Cardiovascular Research

Volumn 59, Issue 2, 2003, Pages 412-418

  Lambermont, Bernard ^a,d   Ghuysen, Alexandre ^a   Kolh, Philippe ^a   Tchana Sato, Vincent ^a   Segers, Patrick ^b   Gérard, Paul ^a   Morimont, Philippe ^a   Magis, David ^a   Dogné, Jean Michel ^a   Masereel, Bernard ^c   D'Orio, Vincent ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITY OF NAMUR   (Belgium)

^d UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Contractile function; Endotoxins; Hemodynamics; Pulmonary circulation; Septic shock

Indexed keywords

ENDOTOXIN; OXYGEN; PLACEBO;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY BLOOD FLOW; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEVICE; DIASTOLE; FEMALE; HEART CATHETER; HEART CONDUCTION; HEART CONTRACTION; HEART RIGHT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE PRESSURE; HEART RIGHT VENTRICLE VOLUME; HEART WORK; INFUSION; LUNG ARTERY PRESSURE; MALE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REGULATORY MECHANISM; SEPTIC SHOCK; SWINE; SYSTOLE; TECHNIQUE;

ANIMALS; BLOOD PRESSURE; ENDOTOXINS; FEMALE; HEART CATHETERIZATION; HEART RATE; MALE; PULMONARY ARTERY; RANDOM ALLOCATION; SHOCK, SEPTIC; SWINE; SYSTOLE; VENTRICULAR DYSFUNCTION, RIGHT;

EID: 10744219631     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(03)00368-7     Document Type: Article

References (31)

1. Freeman B.D., Natanson C. Anti-inflammatory therapies in sepsis and septic shock. Expert Opin Invest Drugs. 9:(7):2000;1651-1663.
2. Kimchi A., Ellrodt A.G., Berman D.S., et al. Right ventricular performance in septic shock: a combined radionuclide and hemodynamic study. J Am Coll Cardiol. 4:(5):1984;945-951.
3. Wojtczak J.A., Szalados J.E. Right heart function: neither silent nor passive. Crit Care Med. 30:(11):2002;2601-2603.
4. Sibbald W.J., Paterson N.A., Holliday R.L., et al. Pulmonary hypertension in sepsis: measurement by the pulmonary arterial diastolic-pulmonary wedge pressure gradient and the influence of passive and active factors. Chest. 73:(5):1978;583-591.
5. Parker M.M., McCarthy K.E., Ognibene F.P., Parrillo J.E. Right ventricular dysfunction and dilatation, similar to left ventricular changes, characterize the cardiac depression of septic shock in humans. Chest. 97:(1):1990;126-131.
6. D'Orio V., Lambermont B., Detry O., et al. Pulmonary impedance and right ventricular-vascular coupling in endotoxin shock. Cardiovasc Res. 38:(2):1998;375-382.
7. Redl G., Abdi S., Traber L.D., et al. Inhibition of thromboxane synthesis reduces endotoxin-induced right ventricular failure in sheep. Crit Care Med. 19:(10):1991;1294-1302.
8. Fourie P.R., Coetzee A.R., Bolliger C.T. Pulmonary artery compliance: its role in right ventricular-arterial coupling. Cardiovasc Res. 26:1992;839-844.
9. Karunanithi M.K., Michniewicz J., Copeland S.E., Feneley M.P. Right ventricular preload recruitable stroke work, end-systolic pressure-volume, and dP/dtmax-end-diastolic volume relations compared as indexes of right ventricular contractile performance in conscious dogs. Circ Res. 70:(6):1992;1169-1179.
10. Szabo G., Sebening C., Hagl C., et al. Right ventricular function after brain death: response to an increased afterload. Eur J Cardiothorac Surg. 13:(4):1998;449-458.
11. De Vroomen M., Steendijk P., Lopes Cardozo R.H., et al. Enhanced systolic function of the right ventricle during respiratory distress syndrome in newborn lambs. Am J Physiol Heart Circ Physiol. 280:(1):2001;H392-H400.
12. Dickstein M.L., Yano O., Spotnitz H.M., Burkhoff D. Assessment of right ventricular contractile state with the conductance catheter technique in the pig. Cardiovasc Res. 29:(6):1995;820-826.
13. Lambermont B., Kolh P., Detry O., et al. Analysis of endotoxin effects on the intact pulmonary circulation. Cardiovasc Res. 41:(1):1999;275-281.
14. Grant B.J.B., Paradowski L.J. Characterization of pulmonary arterial input impedance with lumped parameters models. Am J Physiol. 252:(21):1987;H585-H593.
15. De Vroomen M., Cardozo R.H., Steendijk P., Van Bel F., Baan J. Improved contractile performance of right ventricle in response to increased RV afterload in newborn lamb. Am J Physiol Heart Circ Physiol. 278:(1):2000; H100-H105.
16. Suga H., Hayashi T., Shirahata M. Ventricular systolic pressure-volume area as predictor of cardiac oxygen consumption. Am J Physiol. 240:(1):1981;H39-H44.
17. Burkhoff D., Sagawa K. Ventricular efficiency predicted by an analytical model. Am J Physiol. 250:(6 Pt 2):1986;R1021-R1027.
18. Kass D.A., Kelly R.P. Ventriculo-arterial coupling: concepts,assumptions, and applications. Ann Biomed Eng. 20:1992;41-62.
19. Hon J.K., Steendijk P., Khan H., Wong K., Yacoub M. Acute effects of pulmonary artery banding in sheep on right ventricle pressure-volume relations: relevance to the arterial switch operation. Acta Physiol Scand. 172:(2):2001;97-106.
20. Lopes Cardozo R.H., Steendijk P., Baan J., et al. Right ventricular function in respiratory distress syndrome and subsequent partial liquid ventilation. Homeometric autoregulation in the right ventricle of the newborn animal. Am J Respir Crit Care Med. 162:(2 Pt 1):2000;374-379.
21. Cunnion R.E., Schaer G.L., Parker M.M., Natanson C., Parrillo J.E. The coronary circulation in human septic shock. Circulation. 73:(4):1986;637-644.
22. Sibelius U., Grandel U., Buerke M., et al. Staphylococcal alpha-toxin provokes coronary vasoconstriction and loss in myocardial contractility in perfused rat hearts: role of thromboxane generation. Circulation. 101:(1):2000;78-85.
23. Bloos F.M., Morisaki H.M., Neal A.M., et al. Sepsis depresses the metabolic oxygen reserve of the coronary circulation in mature sheep. Am J Respir Crit Care Med. 153:(5):1996;1577-1584.
24. Court O., Kumar A., Parrillo J.E., Kumar A. Clinical review: myocardial depression in sepsis and septic shock. Crit Care. 6:(6):2002;500-508.
25. Michie H.R., Manogue K.R., Spriggs D.R., et al. Detection of circulating tumor necrosis factor after endotoxin administration. New Engl J Med. 318:(23):1988;1481-1486.
26. Kumar A., Brar R., Wang P., et al. Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility. Am J Physiol. 276:(1 Pt 2):1999;R265-R276.
27. Brady A.J., Poole-Wilson P.A., Harding S.E., Warren J.B. Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am J Physiol. 263:(6 Pt 2):1992;H1963-H1966.
28. Miyano H., Shishido T., Kawada T., et al. Acute effect of tumor necrosis factor-alpha is minimal on mechanics but significant on energetics in blood-perfused canine left ventricles. Crit Care Med. 27:(1):1999;168-176.
29. Silverman H.J., Penaranda R., Orens J.B., Lee N.H. Impaired beta-adrenergic receptor stimulation of cyclic adenosine monophosphate in human septic shock: association with myocardial hyporesponsiveness to catecholamines. Crit Care Med. 21:(1):1993;31-39.
30. Khadour F.H., Panas D., Ferdinandy P., et al. Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats. Am J Physiol Heart Circ Physiol. 283:(3):2002;H1108-H1115.
31. Michie H.R. The value of animal models in the development of new drugs for the treatment of the sepsis syndrome. J Antimicrob Chemother. 41:(Suppl A):1998;47-49.