Novel 99mTc radiolabeled quinazolinone derivative [Qn-In]: Synthesis, evaluation and biodistribution studies in mice and rabbit

Nuclear Medicine and Biology

Volumn 31, Issue 8, 2004, Pages 1087-1095

  Kumari, Saroj ^a   Kalra, Neetu ^a   Mishra, Pushpa ^b   Chutani, Krishna ^b   Mishra, Anil ^b   Chopra, Madhu ^a  

^a UNIVERSITY OF DELHI   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Biodistribution; Breast cancer; Cholecystokinin; Cholecystokinin B gastrin receptors; Nonpeptidic ligand 99mTc labeled Qn In

Indexed keywords

CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ B RECEPTOR ANTAGONIST; QUINAZOLINONE DERIVATIVE; RADIOISOTOPE; TECHNETIUM 99M; DIAGNOSTIC AGENT; HYDRAZONE DERIVATIVE; QUINAZOLINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; TECHNETIUM 99M 3 (4 METHYLPHENYL) 2 (2 (2 OXO 2,3 DIHYDRO 1H INDOL 3 YL)HYDRAZINO)QUINAZOL 4(3H) ONE; TECHNETIUM 99M 3-(4-METHYLPHENYL)-2-(2-(2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL)HYDRAZINO)QUINAZOL-4(3H)-ONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG SYNTHESIS; DRUG UPTAKE; ISOTOPE LABELING; LIGAND BINDING; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RABBIT; ANIMAL; ANTIBODY SPECIFICITY; BREAST TUMOR; CHEMISTRY; COMPARATIVE STUDY; METABOLIC CLEARANCE RATE; METABOLISM; SCINTISCANNING; SPECIES DIFFERENCE; SYNTHESIS; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; HYDRAZONES; METABOLIC CLEARANCE RATE; MICE; ORGAN SPECIFICITY; QUINAZOLINES; RABBITS; RADIOPHARMACEUTICALS; RECEPTOR, CHOLECYSTOKININ B; SPECIES SPECIFICITY; TISSUE DISTRIBUTION;

EID: 10644245226     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2004.03.014     Document Type: Article

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