Mechanism of hydrogen peroxide-induced Cu,Zn-superoxide dismutase-centered radical formation as explored by immuno-spin trapping: The role of copper- and carbonate radical anion-mediated oxidations

Free Radical Biology and Medicine

Volumn 38, Issue 2, 2005, Pages 201-214

  Ramirez, Dario C ^a   Gomez Mejiba, Sandra E ^a   Mason, Ronald P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

5,5 Dimethyl 1 pyrroline N Oxide; Carbonate radical anion; Copper catalyzed oxidation; Cu,Zn superoxide dismutase radical derived nitrone adduct; Dityrosine; Hydrogen peroxide; Immuno spin trapping; Superoxide dismutase

Indexed keywords

CARBONIC ACID; COPPER; CYANIDE; HYDROGEN PEROXIDE; RADICAL; SUPEROXIDE DISMUTASE; ZINC;

ARTICLE; ENZYME ACTIVE SITE; FRAGMENTATION REACTION; NONHUMAN; OXIDATION; PH; PRIORITY JOURNAL;

ANIMALS; ANIONS; BINDING SITES; BLOTTING, WESTERN; CARBON; CATALASE; CATTLE; COPPER; CYSTEINE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FREE RADICALS; HISTIDINE; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; OXIDANTS; OXIDATION-REDUCTION; OXYGEN; PENTETIC ACID; SPIN TRAPPING; SUPEROXIDE DISMUTASE; SUPEROXIDES; TIME FACTORS; TYROSINE;

EID: 10644225292     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.10.008     Document Type: Article

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