The semidominant Mib mutation identifies a role for the HLH domain in DNA binding in addition to its role in protein dimerization

EMBO Journal

Volumn 15, Issue 22, 1996, Pages 6280-6289

  Steingrímsson, Eiríkur ^a   Nii, Aisuke ^a,b   Fisher, David E ^c   Ferré D'Amaré, Adrian R ^d,e   McCormick, Richard J ^c   Russell, Liane B ^f   Burley, Stephen K ^d   Ward, Jerrold M ^a   Jenkins, Nancy A ^a   Copeland, Neal G ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ASTELLAS PHARMA INC   (Japan)

^c HARVARD MEDICAL SCHOOL   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e YALE UNIVERSITY   (United States)

^f OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

bHLH Zip transcription factors; DNA binding; Melanocytes; Microphthalmia; Retinal degeneration

Indexed keywords

HELIX LOOP HELIX PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DIMERIZATION; GENE LOCUS; GENE MUTATION; MAST CELL; MELANOCYTE; MICROPHTHALMIA; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; OSTEOCLAST; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; RECESSIVE INHERITANCE; RETINA DEGENERATION;

ANIMALIA;

EID: 10544249464     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01018.x     Document Type: Article

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