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Volumn 16, Issue 3, 1996, Pages 1203-1211

The recessive phenotype displayed by a dominant negative microphthalmia-associated transcription factor mutant is a result of impaired nuclear localization potential

Author keywords

[No Author keywords available]

Indexed keywords

SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0030068826     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.16.3.1203     Document Type: Article
Times cited : (105)

References (53)
  • 1
    • 0025061096 scopus 로고
    • TFE3: A helix-loop-helix protein that activates transcription through the immunoglobulin enhancer μE3 motif
    • Beckmann, H., L. Su, and T. Kadesch. 1990 TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer μE3 motif. Genes Dev. 4:167-179.
    • (1990) Genes Dev. , vol.4 , pp. 167-179
    • Beckmann, H.1    Su, L.2    Kadesch, T.3
  • 2
    • 0028027745 scopus 로고
    • Melanocyte-specific expression of the human tyrosinase promoter: Activation by the microphthalmia gene product and role of the initiator
    • Bentley, N. J., T. Eisen, and C. R. Goding. 1994. Melanocyte-specific expression of the human tyrosinase promoter: activation by the microphthalmia gene product and role of the initiator. Mol. Cell. Biol. 14:7996-8006.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7996-8006
    • Bentley, N.J.1    Eisen, T.2    Goding, C.R.3
  • 3
    • 0026680845 scopus 로고
    • Interaction cloning: Identification of helix-loop-helix zipper protein that interacts with c-Fos
    • Blanar, M. A., and W. J. Rutter. 1992. Interaction cloning: identification of helix-loop-helix zipper protein that interacts with c-Fos. Science 256:1014-1018.
    • (1992) Science , vol.256 , pp. 1014-1018
    • Blanar, M.A.1    Rutter, W.J.2
  • 4
    • 0025310643 scopus 로고
    • A helix-loop-helix protein related to the immunoglobulin E box-binding proteins
    • Carr, C. S., and P. A. Sharp. 1990. A helix-loop-helix protein related to the immunoglobulin E box-binding proteins Mol. Cell. Biol. 10:4384-4388
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4384-4388
    • Carr, C.S.1    Sharp, P.A.2
  • 6
    • 0026551292 scopus 로고
    • Nuclear translocation of viral Jun but not of cellular Jun is cell cycle dependent
    • Chida, K., and P. K. Vogt. 1992. Nuclear translocation of viral Jun but not of cellular Jun is cell cycle dependent. Proc. Natl. Acad. Sci. USA 89:4290-4294.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4290-4294
    • Chida, K.1    Vogt, P.K.2
  • 7
    • 0023731952 scopus 로고
    • Identification of the human c-myc protein nuclear translocation signal
    • Dang, C. V., and W. M. F. Lee. 1988. Identification of the human c-myc protein nuclear translocation signal. Mol. Cell. Biol. 8:4048-4054.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 4048-4054
    • Dang, C.V.1    Lee, W.M.F.2
  • 8
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Dérijard, B., M. Hibi, I.-H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Dérijard, B.1    Hibi, M.2    Wu, I.-H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 9
    • 0025949412 scopus 로고
    • Nuclear targeting sequences - A consensus?
    • Dingwall, C., and A. Laskey. 1991. Nuclear targeting sequences - a consensus? Trends Biochem. Sci. 16:478-481
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 478-481
    • Dingwall, C.1    Laskey, A.2
  • 12
    • 0017710978 scopus 로고
    • Characteristics of a human cell line transformed by DNA from human adenovirus type 5
    • Graham, F. L., J. Smiley, W. C. Russell, and R. Nairn. 1977. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 36:59-72.
    • (1977) J. Gen. Virol. , vol.36 , pp. 59-72
    • Graham, F.L.1    Smiley, J.2    Russell, W.C.3    Nairn, R.4
  • 13
    • 0002780546 scopus 로고
    • Catalog of mutant genes and polymorphic loci
    • M. F Lyon and A. G. Searle (ed.), Oxford University Press, Oxford
    • Green, M. C. 1989. Catalog of mutant genes and polymorphic loci, p. 236-238. In M. F Lyon and A. G. Searle (ed.), Genetic variants and strains of the laboratory mouse. Oxford University Press, Oxford.
    • (1989) Genetic Variants and Strains of the Laboratory Mouse , pp. 236-238
    • Green, M.C.1
  • 14
    • 0023690369 scopus 로고
    • Two nuclear location signals in the influenza virus NS1 nonstructural protein
    • Greenspan, D., P. Palese, and M. Krystal. 1988. Two nuclear location signals in the influenza virus NS1 nonstructural protein. J. Virol 62:3020-3026.
    • (1988) J. Virol , vol.62 , pp. 3020-3026
    • Greenspan, D.1    Palese, P.2    Krystal, M.3
  • 15
    • 0013319905 scopus 로고
    • The relations of microphthalmia and white in the mouse
    • Grüneberg, H. 1953. The relations of microphthalmia and white in the mouse. J. Genet 51:359-362.
    • (1953) J. Genet , vol.51 , pp. 359-362
    • Grüneberg, H.1
  • 16
    • 0025092335 scopus 로고
    • Homeodomain of yeast repressor α2 contains a nuclear localization signal
    • Hall, M. N., C. Craik, and Y. Hiraoka. 1990. Homeodomain of yeast repressor α2 contains a nuclear localization signal. Proc. Natl. Acad. Sci. USA 87: 6954-6958.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6954-6958
    • Hall, M.N.1    Craik, C.2    Hiraoka, Y.3
  • 17
    • 0021167363 scopus 로고
    • Targeting of E. coli β-galactosidase to the nucleus in yeast
    • Hall, M. N., L. Hereford, and I. Herskowitz. 1984. Targeting of E. coli β-galactosidase to the nucleus in yeast Cell 36:1057-1065.
    • (1984) Cell , vol.36 , pp. 1057-1065
    • Hall, M.N.1    Hereford, L.2    Herskowitz, I.3
  • 18
    • 0025123156 scopus 로고
    • Structure of mouse vasopressin and oxytocin genes
    • Hara, Y., J. Battey, and H. Gainer. 1990. Structure of mouse vasopressin and oxytocin genes. Mol. Brain Res. 8:319-324
    • (1990) Mol. Brain Res. , vol.8 , pp. 319-324
    • Hara, Y.1    Battey, J.2    Gainer, H.3
  • 20
    • 0027204149 scopus 로고
    • Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein
    • Hodgkinson, C. A., K. J. Moore, A. Nakayama, E. Steingrimsson, N. G. Copeland, N. A. Jenkins, and H. Arnheiter. 1993. Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell 74:395-404.
    • (1993) Cell , vol.74 , pp. 395-404
    • Hodgkinson, C.A.1    Moore, K.J.2    Nakayama, A.3    Steingrimsson, E.4    Copeland, N.G.5    Jenkins, N.A.6    Arnheiter, H.7
  • 21
    • 0013320032 scopus 로고
    • Complementary alleles at the mi-locus in the mice
    • Hollander, W. F. 1968. Complementary alleles at the mi-locus in the mice. Genetics 60:189.
    • (1968) Genetics , vol.60 , pp. 189
    • Hollander, W.F.1
  • 22
    • 0027386022 scopus 로고
    • A helix-loop-helix transcription factor-like gene is located at the mi locus
    • Hughes, M. J., J. B. Lingrel, J. M. Krakowsky, and K. P. Anderson. 1993. A helix-loop-helix transcription factor-like gene is located at the mi locus. J. Biol. Chem. 268:20687-20690.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20687-20690
    • Hughes, M.J.1    Lingrel, J.B.2    Krakowsky, J.M.3    Anderson, K.P.4
  • 24
    • 0026486816 scopus 로고
    • Pleiotropic effects of a null mutation in the c-fos proto-oncogene
    • Johnson, R. S., B. M. Spiegelman, and V. Papaioannou. 1992. Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell 71:577-586.
    • (1992) Cell , vol.71 , pp. 577-586
    • Johnson, R.S.1    Spiegelman, B.M.2    Papaioannou, V.3
  • 25
    • 0021716406 scopus 로고
    • A short amino acid sequence able to specify nuclear location
    • Kalderon, D., B. L. Roberts, W. D. Richardson, and A. E. Smith. 1984. A short amino acid sequence able to specify nuclear location. Cell 39:499-509.
    • (1984) Cell , vol.39 , pp. 499-509
    • Kalderon, D.1    Roberts, B.L.2    Richardson, W.D.3    Smith, A.E.4
  • 27
    • 0027346954 scopus 로고
    • A DNA insertional mutation results in microphthalmia in transgenic mice
    • Krakowsky, J. M., R. E. Biossy, J. C. Neumann, and J. B. Lingrel. 1993. A DNA insertional mutation results in microphthalmia in transgenic mice. Transgenic Res. 2:14-20.
    • (1993) Transgenic Res. , vol.2 , pp. 14-20
    • Krakowsky, J.M.1    Biossy, R.E.2    Neumann, J.C.3    Lingrel, J.B.4
  • 28
    • 0022460644 scopus 로고
    • Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal
    • Lanford, R. E., P. Kanda, and R. C. Kennedy. 1986. Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal. Cell 46:575-582.
    • (1986) Cell , vol.46 , pp. 575-582
    • Lanford, R.E.1    Kanda, P.2    Kennedy, R.C.3
  • 29
    • 0019423009 scopus 로고
    • The hematogenous origin of osteoclasts: Experimental evidence from osteopetrotic (microphthalmic) mice treated with spleen cells from beige mouse donors
    • Marks, S. C., Jr., and D. G. Walker. 1981. The hematogenous origin of osteoclasts: experimental evidence from osteopetrotic (microphthalmic) mice treated with spleen cells from beige mouse donors. Am. J. Anat. 161: 1-10.
    • (1981) Am. J. Anat. , vol.161 , pp. 1-10
    • Marks Jr., S.C.1    Walker, D.G.2
  • 30
    • 0024991898 scopus 로고
    • pEF-BOS, a powerful mammalian expression vector
    • Mizushima, S., and S. Nagata. 1990. pEF-BOS, a powerful mammalian expression vector Nucleic Acids Res. 18:5322.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 5322
    • Mizushima, S.1    Nagata, S.2
  • 32
    • 0027960698 scopus 로고
    • Dysgenesis of melanocytes and cochlear dysfunction in mutant microphthalmia (mi) mice
    • Motohashi, H., K. Hozawa, T. Oshima, T. Takeuchi, and T. Takasaka. 1994. Dysgenesis of melanocytes and cochlear dysfunction in mutant microphthalmia (mi) mice. Hear. Res. 80:19-20.
    • (1994) Hear. Res. , vol.80 , pp. 19-20
    • Motohashi, H.1    Hozawa, K.2    Oshima, T.3    Takeuchi, T.4    Takasaka, T.5
  • 33
    • 0027154720 scopus 로고
    • Identification of a novel interleukin-6 response element containing an Ets-binding site and a CRE-like site in the junB promoter
    • Nakajima, K., T. Kusafuka, T. Takeda, Y. Fujitani, K. Nakae, and T. Hirano. 1993. Identification of a novel interleukin-6 response element containing an Ets-binding site and a CRE-like site in the junB promoter. Mol. Cell. Biol. 13:3027-3041.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3027-3041
    • Nakajima, K.1    Kusafuka, T.2    Takeda, T.3    Fujitani, Y.4    Nakae, K.5    Hirano, T.6
  • 34
    • 0023441954 scopus 로고
    • Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor
    • Picard, D., and K. R. Yamamoto. 1987 Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. EMBO J. 6: 3333-3340.
    • (1987) EMBO J. , vol.6 , pp. 3333-3340
    • Picard, D.1    Yamamoto, K.R.2
  • 35
    • 0022546215 scopus 로고
    • Nuclear location signals in polyoma virus large-T
    • Richardson, W. D., B. L. Roberts, and A. E. Smith. 1986. Nuclear location signals in polyoma virus large-T. Cell 44:77-85
    • (1986) Cell , vol.44 , pp. 77-85
    • Richardson, W.D.1    Roberts, B.L.2    Smith, A.E.3
  • 36
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
    • Ron, D., and J. F. Harbener. 1992. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 6:439-453.
    • (1992) Genes Dev. , vol.6 , pp. 439-453
    • Ron, D.1    Harbener, J.F.2
  • 37
    • 0024041259 scopus 로고
    • A mutant SV40 large T antigen interferes with nuclear localization of a heterologous protein
    • Schneider, J., C. Schindewolf, K. van Zee, and E. Fanning. 1988. A mutant SV40 large T antigen interferes with nuclear localization of a heterologous protein. Cell 54:117-125
    • (1988) Cell , vol.54 , pp. 117-125
    • Schneider, J.1    Schindewolf, C.2    Van Zee, K.3    Fanning, E.4
  • 38
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber, E., P. Matthias, M. M. Müller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells Nucleic Acids Res. 17:6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Müller, M.M.3    Schaffner, W.4
  • 39
    • 0025260987 scopus 로고
    • A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteme - Serine substitution at position 85
    • Shibahara, S., S. Okinaga, Y. Tomita, A. Takeda, H. Yamamoto, M. Sato, and T. Takeuchi. 1990. A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteme - serine substitution at position 85. Eur J Biochem. 189:455-461.
    • (1990) Eur J Biochem. , vol.189 , pp. 455-461
    • Shibahara, S.1    Okinaga, S.2    Tomita, Y.3    Takeda, A.4    Yamamoto, H.5    Sato, M.6    Takeuchi, T.7
  • 41
    • 0023806075 scopus 로고
    • Single-step purification of polypeptides expressed in Escherichia coli as fusions with slutathione S-transferase
    • Smith, D. B., and K. S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with slutathione S-transferase. Gene 67:31-40.
    • (1988) Gene , vol.67 , pp. 31-40
    • Smith, D.B.1    Johnson, K.S.2
  • 44
    • 0019954883 scopus 로고
    • Mast cells in spotted mutant mice (W Ph mi)
    • Stevens, J., and J. F. Loutit. 1982. Mast cells in spotted mutant mice (W Ph mi). Proc. R. Soc. Lond. Ser B 215:405-409.
    • (1982) Proc. R. Soc. Lond. Ser B , vol.215 , pp. 405-409
    • Stevens, J.1    Loutit, J.F.2
  • 46
    • 0028306459 scopus 로고
    • Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
    • Turner, D. L., and H. Weintraub. 1994. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev. 8:1434-1447.
    • (1994) Genes Dev. , vol.8 , pp. 1434-1447
    • Turner, D.L.1    Weintraub, H.2
  • 47
    • 0025021189 scopus 로고
    • Characterization of nuclear localization sequences derived from yeast ribosomal protein L29
    • Underwood, M. R., and H. M. Fried. 1990. Characterization of nuclear localization sequences derived from yeast ribosomal protein L29. EMBO J. 9:91-100.
    • (1990) EMBO J. , vol.9 , pp. 91-100
    • Underwood, M.R.1    Fried, H.M.2
  • 48
    • 0016811449 scopus 로고
    • Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells
    • Walker, D. G. 1975. Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells. Science 190:784-785.
    • (1975) Science , vol.190 , pp. 784-785
    • Walker, D.G.1
  • 49
    • 0016700933 scopus 로고
    • Spleen cells transmit osteopetrosis in mice
    • Walker, D. G. 1975 Spleen cells transmit osteopetrosis in mice. Science 190: 785-787.
    • (1975) Science , vol.190 , pp. 785-787
    • Walker, D.G.1
  • 52
    • 0028051530 scopus 로고
    • Microphthalmia-associated transcription factor as a regulator for melanocytc-specific transcription of the human tyrosinase gene
    • Yasumoto, K., K. Yokoyama, K. Shibata, Y. Tomita, and S. Shibahara. 1994. Microphthalmia-associated transcription factor as a regulator for melanocytc-specific transcription of the human tyrosinase gene. Mol. Cell Biol. 14: 8058-8070
    • (1994) Mol. Cell Biol. , vol.14 , pp. 8058-8070
    • Yasumoto, K.1    Yokoyama, K.2    Shibata, K.3    Tomita, Y.4    Shibahara, S.5
  • 53
    • 0027219255 scopus 로고
    • TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation
    • Zhao, G.-Q., Q. Zhao, X. Zhou, M. Mattei, and B. De Crombrugghe. 1993. TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation. Mol Cell Biol 13:4505-4512
    • (1993) Mol Cell Biol , vol.13 , pp. 4505-4512
    • Zhao, G.-Q.1    Zhao, Q.2    Zhou, X.3    Mattei, M.4    De Crombrugghe, B.5


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