Efficacy and tolerability of a selective α2C-adrenergic receptor blocker in recovery from cold-induced vasospasm in scleroderma patients: A single-center, double-blind, placebo-controlled, randomized crossover study

Arthritis and Rheumatism

Volumn 50, Issue 12, 2004, Pages 3994-4001

  Wise, Robert A ^a   Wigley, Fredrick M ^a   White, Barbara ^b   Leatherman, Gwen ^a   Zhong, Jianhua ^c   Krasa, Holly ^c   Kambayashi, Jun Ichi ^c   Orlandi, Cesare ^c   Czerwiec, Frank S ^c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c OTSUKA PHARMACEUTICAL DEVELOPMENT AND COMMERCIALIZATION INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; OPC 28326;

ARTICLE; BLOOD FLOW; CLINICAL ARTICLE; CLINICAL TRIAL; COLD EXPOSURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG SELECTIVITY; DRUG TOLERABILITY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RAYNAUD PHENOMENON; RECEPTOR AFFINITY; SCLERODERMA; SIDE EFFECT; SKIN TEMPERATURE; TREATMENT OUTCOME; VASOSPASM;

ADMINISTRATION, ORAL; ADOLESCENT; ADRENERGIC ALPHA-ANTAGONISTS; ADULT; AGED; AGED, 80 AND OVER; ANILINE COMPOUNDS; COLD; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FINGERS; HUMANS; MALE; MIDDLE AGED; PIPERIDINES; RAYNAUD DISEASE; REGIONAL BLOOD FLOW; SCLERODERMA, SYSTEMIC; SKIN TEMPERATURE; VASODILATION;

EID: 10444279222     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.20665     Document Type: Article

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