Genetic approaches to alcohol dependence

British Journal of Psychiatry

Volumn 185, Issue DEC., 2004, Pages 449-451

  Ball, David ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ALDEHYDE DEHYDROGENASE ISOENZYME 2; DOPAMINE 2 RECEPTOR;

ALCOHOL METABOLISM; ALCOHOLISM; DNA SEQUENCE; EDITORIAL; ENZYME ACTIVITY; FAMILY STUDY; GABAERGIC SYSTEM; GENE CLUSTER; GENETIC ANALYSIS; GENETIC COUNSELING; GENETIC LINKAGE; HERITABILITY; MOLECULAR GENETICS; PROGNOSIS;

ALCOHOL DEHYDROGENASE; ALCOHOLISM; ALDEHYDE DEHYDROGENASE; BIOMEDICAL RESEARCH; GENETIC PREDISPOSITION TO DISEASE; HUMANS;

EID: 10444277247     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.185.6.449     Document Type: Editorial

References (20)

1. Ball, D. & Collier, D. (2002) Substance misuse. In Psychiatric Genetics and Genomics (eds P. McGuffin, M. Owen & I.I. Gottesman), pp. 267-302. Oxford: Oxford University Press.
2. Blum, K., Noble, E. P., Sheridan, P. J., et al (1990) Allelic association of human dopamine D2 receptor gene in alcoholism. JAMA, 263, 2055-2060.
3. Buckland, P. R. (2001) Genetic association studies of alcoholism - problems with the candidate gene approach. Alcohol and Alcoholism, 36, 99-103.
4. Burton, R. (1972) The Anatomy of Melancholy. London: Dent.
5. Caspi, A., McClay, J., Moffitt, T. E., et al (2002) Role of genotype in the cycle of violence in maltreated children. Science, 297, 851-854.
6. Caspi, A., Sugden, K., Moffitt, T. E., et al (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science, 301, 386-389.
7. Chen, Y. C., Lu, R. B., Peng, G. S., et al (1999) Alcohol metabolism and cardiovascular response in an alcoholic patient homozygous for the ALDH2*2 variant gene allele. Alcoholism: Clinical and Experimental Research, 23, 1853-1860.
8. Dick, D. M. & Foroud, T. (2003) Candidate genes for alcohol dependence: a review of genetic evidence from human studies. Alcoholism: Clinical and Experimental Research, 27, 868-879.
9. Hesselbrock, V., Foroud, T., Edenberg, H. J., et al (2001) Genetics and alcoholism: the COGA Project. In Alcohol in Health and Disease (eds D. P. Agarwal & H. K. Seitz), pp. 103-124. New York: Marcel Dekker.
10. A2 receptor subunit genes cluster in drug responses and the development of alcohol dependence. Neurochemistry International, 37, 413-423.
11. Loh, E. W., Smith, I., Murray, R., et al (1999) Association between variants at the GABAAbeta2, GABAAalpha6 and GABAAgamma2 gene cluster and alcohol dependence in a Scottish population. Molecular Psychiatry, 4, 539-544.
12. A receptor subunit genes cluster on 5q33-34 and alcohol dependence in a Japanese population. Molecular Psychiatry, 5, 301-307.
13. Long, J. C., Knowler, W. C., Hanson, R. L., et al (1998) Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population. American Journal of Medical Genetics, 81, 216-221.
14. Nuffield Council on Bioethics (1998) Mental Disorders and Genetics: The Ethical Context. London: Nuffield Council on Bioethics. http://www. nuffieldbioethics.org/go/ourwork/mentaldisorders/introduction
15. Plutarch (110) The Training of Children, http://www.fordham.edu/halsall/ ancient/plutarch-educational.html
16. Reich, T., Edenberg, H. J., Goate, A., et al (1998) Genome-wide search for genes affecting the risk of alcohol dependence. American Journal of Medical Genetics, 81, 207-215.
17. Sander, T., Ball, D., Murray, R., et al (1999) Association analysis of sequence variants of GABA(A) alpha6, beta2, and gamma2 gene cluster and alcohol dependence. Alcoholism: Clinical and Experimental Research, 23, 427-431.
18. Sham, P. & McGuffin, P. (2002) Linkage and association. In Psychiatric Genetics and Genomics (eds P. McGuffin, M. Owen & I.I. Gottesman), pp. 55-73. Oxford: Oxford University Press.
19. Wolff, P. H. (1972) Ethnic differences in alcohol sensitivity. Science, 175, 449-450.
20. Yin, S. J. & Agarwal, D. P. (2001) Functional polymorphisms of ADH and ALDH. In Alcohol in Health and Disease (eds D. P. Agarwal & H. K. Seitz), pp. 1-26. New York: Marcel Dekker.