Metabolism of tryptophan along the kynurenine pathway in alloxan diabetic rabbits

Advances in Experimental Medicine and Biology

Volumn 527, Issue , 2003, Pages 387-393

  Allegri, Graziella ^a   Zaccarin, Delia ^a   Ragazzi, Eugenio ^b   Froldi, Guglielmina ^b   Bertazzo, Antonella ^a   Costa, Carlo V L ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b Dept of Pharmacol and Anaesthiol ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYANTHRANILATE 3,4 DIOXYGENASE; ALLOXAN; AMINOCARBOXYMUCOLATE SEMIALDEHYDE DECARBOXYLASE; HOLOENZYME; INDOLE 2,3 DIOXYGENASE; KYNURENINASE; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; KYNURENINE OXOGLUTARATE TRANSAMINASE; TRYPTOPHAN 2,3 DIOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; CHOLESTEROL DIET; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; KIDNEY; LIVER; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMALL INTESTINE; STATISTICAL SIGNIFICANCE; TRYPTOPHAN METABOLISM;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 1042302731     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0135-0_45     Document Type: Conference Paper

References (12)

1. A. Bertazzo, E. Ragazzi, M. Biasiolo, C.V.L. Costa, G Allegri, Enzyme activities involved in tryptophan metabolism along the kynurenine pathway in rabbits, Biochim. Biophys. Acta 1527, 167-175 (2001).
2. L.M. Henderson, G.B. Ramasarma, B.C. Johnson, Quinolinic acid metabolism IV. Urinary excretion by man and other mammals as affected by the ingestion of tryptophan, J. Biol. Chem. 181, 731-738 (1949).
3. A.C. Da Silva, R. Fried, R.C. De Angelis, The domestic cat as a laboratory animal for experimental nutrition studies, J. Nutr. 46, 399-409 (1952).
4. E.G. McDaniel, J.M. Hundley, W.H. Sebrell, Tryptophan-niacin metabolism in alloxan diabetic rats, J. Nutr. 59, 407-423 (1956).
5. A.H. Mehler, E.G. McDaniel, J.M. Hundley, Changes in the enzymatic composition of liver I. Increase of aminocarboxymuconate-semialdehyde decarboxylase in diabetes, J. Biol. Chem. 232, 323-330 (1958).
6. J.M. Schor and E. Frieden, Induction of tryptophan peroxidase of rat liver by insulin and alloxan, J. Biol. Chem. 233, 612-618 (1958).
7. N.B. Ruderman, S. Gupta, I. Sussman, Hyperglycemia, diabetes, and vascular disease: an overview, in: Hyperglycemia, Diabetes, and Vascular Disease, edited by N. Ruderman, J. Williamson, M. Brownlee (Oxford University Press, New York, 1992), pp. 3-20.
8. J.L. Dixon, J.D. Stoops, J.L. Parker, M.H. Laughlin, G.A. Weisman, M. Sturek, Dyslipidemia and vascular dysfunction in diabetic pigs fed an atherogenic diet, Arterioscler. Thromb. Vasc. Biol. 19, 2981-2992 (1999).
9. E. Ragazzi, C.L.V. Costa, L. Caparrotta, M. Biasiolo, A. Bertazzo, G. Allegri, Enzyme activities along the tryptophan-nicotinic acid pathway in alloxan diabetic rabbits. Biochim. Biophys. Acta, 1571, 9-17 (2002).
10. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall, Protein measurement with the Polin phenol reagent, J. Biol. Chem. 193, 265-275 (1951).
11. A.A-B. Badawy & M. Evans, Animal liver tryptophan pyrrolases. Absence of apoenzyme and of hormonal induction mechanism from species sensitive to tryptophan toxicity, Biochem. J. 158, 79-88 (1976).
12. E. Ginoulhiac, L.T. Tenconi, U. Bonomi, Attività enzimatiche della linea triptofano-acido nicotinico nel diabete da pancreasectomia del ratto, Acta Vitamin. (Milano) 18, 205-216 (1964).