Improvement of temperature and flow in feet of subjects with diabetes with use of a transdermal preparation of L-arginine: A pilot study [13]

Diabetes Care

Volumn 27, Issue 1, 2004, Pages 284-285

  Fossel, Eric T ^a  

^a Strategic Science and Technologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; PLACEBO;

ADULT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; CROSSOVER PROCEDURE; DIABETES MELLITUS; DIABETIC ANGIOPATHY; DIABETIC FOOT; DOPPLER FLOWMETER; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HUMAN; LEG BLOOD FLOW; LETTER; TEMPERATURE;

ADMINISTRATION, CUTANEOUS; ARGININE; DIABETIC FOOT; DOUBLE-BLIND METHOD; FOOT; HUMANS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; REGIONAL BLOOD FLOW; SKIN TEMPERATURE;

EID: 1042291843     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.27.1.284     Document Type: Letter

References (7)

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3. Kin KY, Ito A, Asagami T, Tsai PSS, Adimoolan S, Kimoto M, Hideaki T, Reaven GM, Cooke JP: Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethyoaminohydrolase. Circulation 106:987-992, 2002
4. Panda K, Rosenfeld RF, Ghosh S, Meade AL, Getzoff ED, Stuehr DJ: Distinct dimer interaction and regulation in nitric oxide synthase types I, II, and III. J Biol Chem 277:31020-31030, 2002
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6. Abbasi F, Asagmi T, Cooke JP, Lamendola C, McLaughlin T, Reaven GM, Stuehlinger M, Tsao PS: Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus. Am J Cardiol 88:1201-1203, 2001
7. Vongsavan N, Matthews B: Some aspects of the use of laser doppler flow meters for recording tissue blood flow. Exper Physiol 78:1-14, 1993