메뉴 건너뛰기




Volumn 10, Issue 3, 2004, Pages 1160-1169

Synergistic Cytotoxicity of Pyrazoloacridine with Doxorubicin, Etoposide, and Topotecan in Drug-Resistant Tumor Cells

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 DIMETHYLAMINOETHYL) 9 METHOXY 5 NITROPYRAZOLO[3,4,5 KL]ACRIDINE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; TOPOTECAN;

EID: 1042290309     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-1044-3     Document Type: Article
Times cited : (8)

References (32)
  • 1
    • 0032826587 scopus 로고    scopus 로고
    • Current status of pyrazoloacridine as an anticancer agent
    • Adjei, A. A. Current status of pyrazoloacridine as an anticancer agent. Investig. New Drugs Review, 1791: 43-48, 1999.
    • (1999) Investig. New Drugs Review , vol.1791 , pp. 43-48
    • Adjei, A.A.1
  • 2
    • 0023218399 scopus 로고
    • Pyrazoloacridines, a new class of anticancer agents with selectivity agains solid tumors in vitro
    • Sebolt, J. S., Scavone, S. V., Pinter, C. D., Hamelehle, K. L., Von Hoff, D. D., and Jackson, R. C. Pyrazoloacridines, a new class of anticancer agents with selectivity agains solid tumors in vitro. Cancer Res., 47: 4299-4304, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 4299-4304
    • Sebolt, J.S.1    Scavone, S.V.2    Pinter, C.D.3    Hamelehle, K.L.4    Von Hoff, D.D.5    Jackson, R.C.6
  • 3
    • 0024995727 scopus 로고
    • The pyrazoloacridines: Approaches to the development of a carcinoma-selective cytotoxic agent
    • Jackson, R., Sebolt, J. S., Shillis, J. L., and Leopold, W. R. The pyrazoloacridines: approaches to the development of a carcinoma-selective cytotoxic agent. Cancer Investig., 8: 39-47, 1990.
    • (1990) Cancer Investig. , vol.8 , pp. 39-47
    • Jackson, R.1    Sebolt, J.S.2    Shillis, J.L.3    Leopold, W.R.4
  • 5
    • 0039849011 scopus 로고
    • Solid tumor selectivity of the 2-aminoalky-5-nitro-pyrazrolo(3, 4, 5-kl)acridines, a novel class of DNA-binding antitumor agents
    • Sebolt, J. S., Leopold, W. R., Hamelehle, K. L., Pinter, C. D., and Plowman, J. Solid tumor selectivity of the 2-aminoalky-5-nitro-pyrazrolo(3, 4, 5-kl)acridines, a novel class of DNA-binding antitumor agents. Proc. Am. Assoc. Cancer Res., 27: 421, 1986.
    • (1986) Proc. Am. Assoc. Cancer Res. , vol.27 , pp. 421
    • Sebolt, J.S.1    Leopold, W.R.2    Hamelehle, K.L.3    Pinter, C.D.4    Plowman, J.5
  • 7
    • 0025331434 scopus 로고
    • Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell line
    • Cole, S. P. Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell line. Cancer Chemother. Pharmacol., 26: 250-256, 1990.
    • (1990) Cancer Chemother. Pharmacol. , vol.26 , pp. 250-256
    • Cole, S.P.1
  • 13
    • 0030908801 scopus 로고    scopus 로고
    • Phase II study of pyrazoloacridine in patients with advanced colorectal carcinoma
    • Zalupski, M. M., Philip, P. A., LoRusso, P., and Shields, A. F. Phase II study of pyrazoloacridine in patients with advanced colorectal carcinoma. Cancer Chemother. Pharmacol., 40: 225-227, 1997.
    • (1997) Cancer Chemother. Pharmacol. , vol.40 , pp. 225-227
    • Zalupski, M.M.1    Philip, P.A.2    LoRusso, P.3    Shields, A.F.4
  • 15
    • 0033890184 scopus 로고    scopus 로고
    • Phase II trial of pyrazoloacridine as second-line therapy for patients with unresectable or metastatic transitional cell carcinoma
    • Dodd, P. M., McCaffrey, J. A., Mazumdar, M., Icasiano, E., Higgins, G., Herr, H., and Bajorin, D. F. Phase II trial of pyrazoloacridine as second-line therapy for patients with unresectable or metastatic transitional cell carcinoma. Investig. New Drugs, 18: 247-251, 2000.
    • (2000) Investig. New Drugs , vol.18 , pp. 247-251
    • Dodd, P.M.1    McCaffrey, J.A.2    Mazumdar, M.3    Icasiano, E.4    Higgins, G.5    Herr, H.6    Bajorin, D.F.7
  • 17
    • 0034869970 scopus 로고    scopus 로고
    • Phase II study of pyrazoloacridine in metastatic renal cell carcinoma
    • Kuebler, J. P., King, G. W., Triozzi, P., Moore, T., and Kraut, E. H. Phase II study of pyrazoloacridine in metastatic renal cell carcinoma. Investig. New Drugs, 19: 327-328, 2001.
    • (2001) Investig. New Drugs , vol.19 , pp. 327-328
    • Kuebler, J.P.1    King, G.W.2    Triozzi, P.3    Moore, T.4    Kraut, E.H.5
  • 18
    • 0031662119 scopus 로고    scopus 로고
    • Pyrazoloacridine for the treatment of hormone-refractory prostate cancer
    • Small, E. J., Fippin, L. J., and Whisenant, S. P. Pyrazoloacridine for the treatment of hormone-refractory prostate cancer. Cancer Investig., 16: 456-461, 1998.
    • (1998) Cancer Investig. , vol.16 , pp. 456-461
    • Small, E.J.1    Fippin, L.J.2    Whisenant, S.P.3
  • 19
    • 0036141074 scopus 로고    scopus 로고
    • Phase II trial of pyrazoloacridine in recurrent platinum-sensitive ovarian cancer: A Gynecol. Oncol. Group study
    • Plaxe, S. C., Blessing, J. A., Bookman, M. A., and Creasman, W. T. Phase II trial of pyrazoloacridine in recurrent platinum-sensitive ovarian cancer: a Gynecol. Oncol. Group study. Gynecol. Oncol., 84: 32-35, 2002.
    • (2002) Gynecol. Oncol. , vol.84 , pp. 32-35
    • Plaxe, S.C.1    Blessing, J.A.2    Bookman, M.A.3    Creasman, W.T.4
  • 20
    • 0036161934 scopus 로고    scopus 로고
    • Phase II trial of pyrazoloacridine in recurrent platinum-resistant ovarian cancer: A Gynecol. Oncol. Group study
    • Plaxe, S. C., Blessing, J. A., Morgan, M. A., and Carlson, J. Phase II trial of pyrazoloacridine in recurrent platinum-resistant ovarian cancer: a Gynecol. Oncol. Group study. Am. J. Clin. Oncol., 25: 45-47, 2002.
    • (2002) Am. J. Clin. Oncol. , vol.25 , pp. 45-47
    • Plaxe, S.C.1    Blessing, J.A.2    Morgan, M.A.3    Carlson, J.4
  • 21
    • 0029036955 scopus 로고
    • The search for synergy: A critical review from a response surface perspective
    • Greco, W. R., Bravo, G., and Parsons, J. C. The search for synergy: a critical review from a response surface perspective. Pharmacol. Rev., 47: 331-385, 1995.
    • (1995) Pharmacol. Rev. , vol.47 , pp. 331-385
    • Greco, W.R.1    Bravo, G.2    Parsons, J.C.3
  • 22
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou, T. C., and Talalay, P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul., 22: 27-55, 1984.
    • (1984) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 23
    • 0028363549 scopus 로고
    • Quantification of topoisomerase-DNA complexes in leukemia cells from patients undergoing therapy with a topoisomerase-directed agent
    • Ellis, A. L., Nowak, B., Plunkett, W., and Zwelling, L. A. Quantification of topoisomerase-DNA complexes in leukemia cells from patients undergoing therapy with a topoisomerase-directed agent. Cancer Chemother. Pharmacol., 34: 249-256, 1994.
    • (1994) Cancer Chemother. Pharmacol. , vol.34 , pp. 249-256
    • Ellis, A.L.1    Nowak, B.2    Plunkett, W.3    Zwelling, L.A.4
  • 24
    • 0343927426 scopus 로고
    • Cytotoxicity and cell-associated levels of pyrazoloacridine in human multidrug resistant tumor cell lines
    • Politi, P. M., Berg, S. L., Balis, F. M., Poplack, D. G., Allegra, C. J., and Grem, J. L. Cytotoxicity and cell-associated levels of pyrazoloacridine in human multidrug resistant tumor cell lines. Proc. Am. Assoc. Cancer Res., 33: 524, 1992.
    • (1992) Proc. Am. Assoc. Cancer Res. , vol.33 , pp. 524
    • Politi, P.M.1    Berg, S.L.2    Balis, F.M.3    Poplack, D.G.4    Allegra, C.J.5    Grem, J.L.6
  • 26
  • 27
    • 0027932577 scopus 로고
    • Multilevel therapeutic targeting by topoisomerase inhibitors
    • Smith, P. J., and Soues, S. Multilevel therapeutic targeting by topoisomerase inhibitors. Br. J. Cancer, 23: S47, 1994.
    • (1994) Br. J. Cancer , vol.23
    • Smith, P.J.1    Soues, S.2
  • 28
    • 0020684494 scopus 로고
    • Effect of anthracycline antibiotics on oxygen radical formation in rat heart
    • Doroshow, J. H. Effect of anthracycline antibiotics on oxygen radical formation in rat heart. Cancer Res., 43: 460-472, 1983.
    • (1983) Cancer Res. , vol.43 , pp. 460-472
    • Doroshow, J.H.1
  • 29
    • 0023858067 scopus 로고
    • Abrogation of etoposide-mediated cytotoxicity by cycloheximide
    • Chow, K. C., King, C. K., and Ross, W. E. Abrogation of etoposide-mediated cytotoxicity by cycloheximide. Biochem. Pharmacol., 37: 1117-1122, 1988.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 1117-1122
    • Chow, K.C.1    King, C.K.2    Ross, W.E.3
  • 30
    • 0025768873 scopus 로고
    • Etoposide-induced DNA damage in human tumor cells: Requirement for cellular activating factors
    • Sinha, B. K., and Eliot, H. M. Etoposide-induced DNA damage in human tumor cells: requirement for cellular activating factors. Biochim. Biophys. Acta, 1097: 111-116, 1991.
    • (1991) Biochim. Biophys. Acta , vol.1097 , pp. 111-116
    • Sinha, B.K.1    Eliot, H.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.