Effect of Ethanol Extracts of Three Chinese Medicinal Plants with Anti-diarrheal Properties on Ion Transport of the Rat Intestinal Epithelia

Journal of Pharmacological Sciences

Volumn 94, Issue 1, 2004, Pages 60-66

  Tsai, Jong Chang ^a   Tsai, Shuli ^b   Chang, Weng Cheng ^b  

^a NATIONAL CHANGHUA UNIVERSITY OF EDUCATION   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Anti diarrhea; Chinese medicinal plant; Intestinal epithelia; Ion transport; Ussing chamber

Indexed keywords

ALCOHOL; ANTIDIARRHEAL AGENT; BUMETANIDE; COPTIS TEETA EXTRACT; FORSKOLIN; FRAXINI CORTEX EXTRACT; OUABAIN; PLANT EXTRACT; SOPHORA FLAVESCENS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHINESE; CHLORIDE TRANSPORT; CONTROLLED STUDY; COPTIS; DRUG MECHANISM; FRAXINI CORTEX; INTESTINE EPITHELIUM; ION TRANSPORT; MALE; MEDICINAL PLANT; NONHUMAN; RAT; SHORT CIRCUIT CURRENT; SODIUM TRANSPORT; SOPHORA; VOLTAGE CLAMP;

COPTIS TEETA; FRAXINI CORTEX; SOPHORA FLAVESCENS;

EID: 1042279612     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.94.60     Document Type: Article

References (36)

1. Yen CH. The pharmacology of Chinese plants. 1st. Taipei: Chin-Yin Publishing; 1994. p. 160-225. (text in Chinese)
2. Powell DW, Binder HJ, Curran PF. Electrolyte secretion by the guinea pig ileum in vitro. Am J Physiol. 1972;223:531-537.
3. Fondacaro JD. Intestinal ion transport and diarrheal disease. Am J Physiol. 1986;250;G1-G8.
4. Rabbani GH, Greenough WB. Textbook of secretory diarrhea. Lebenthal E, Duffey ME, editors. New York: Raven Press; 1990. p. 233-255.
5. Schultz SG, Frizzell RA. An overview of intestinal absorptive and secretory processes. Gastroenterology. 1972;63:161-170.
6. Hawker PC, Mashiter KE, Turnberg LA. Mechanisms of transport of Na, Cl, and K in the human colon. Gastroenterology. 1978;74:1241-1247.
7. Holtug K, Hansen MB, Skadhauge E. Experimental studies of intestinal ion and water transport. Scand J Gastroenterol. 1996;31 Suppl 216:95-110.
8. Davidson GP, Gall DG, Pertic M, Butler DG, Hamilton JR. Human rotavirus enteritis induced in conventional piglets. Intestinal structure and transport. J Clin Invest. 1977;60:1402-1409.
9. McEwan GT, Schousboe B, Skadhauge E. Effect of anti-secretory factor on Escherichia coli STs enterotoxin-induced alkalinisation of pig. Pflugers Arch. 1990;417:174-179.
10. Osman NE, Westrom B, Karlsson B. Serosal but not mucosal endotoxin exposure increases intestinal permeability in vitro in the rat. Scand J Gastroenterol. 1998;33:1170-1174.
11. Starkey WG, Candy DC, Thornber D, et al. An in vitro model to study aspects of the pathophysiology of murine rotavirus-induced diarrhea. J Pediatr Gastroenterol Nutr. 1990;10:361-370.
12. Field M, Fromm D, Mccoll I. Ion transport in rabbit ileal mucosa. 1. Na and Cl fluxes and short circuit current. Am J Physiol. 1971;220:1388-1396.
13. Kurkchubasche AG, Cardona M, Watkins SC, et al. Transmucosal passage of bacteria across rat intestinal epithelium in the Ussing Chamber: effect of nutritional factors and bacterial virulence. Shock. 1998;9:121-127.
14. Sharp GWG, Hynie S. Stimulation of intestinal adenyl cyclase by cholera toxin. Nature. 1971;229:266-269.
15. Tsai JC, Tsai S, Chang WC. Effect of ethanol extracts of three Chinese medicinal plants with laxative properties on ion transport of the rat intestinal epithelia. Biol Pharm Bull. In press.
16. Neichi T, Koshihara Y, Murota S. Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis. Biochim Biophys Acta. 1983;753:130-132.
17. Taylor CT, Winter DC, Skelly MM, et al. Berberine inhibits ion transport in human colonic epithelia. Eur J Pharmacol. 1999;368:111-118.
18. Cao JW, Luo HS, Yu BP, Huang XD, Sheng ZX, Yu JP. Effects of berberine on intracellular free calcium in smooth muscle cells of guinea pig colon. Digestion. 2001;64:179-183.
19. Kimberg DV, Field M, Johnson J, Henderson A, Gershon E. Stimulation of intestinal mucosal adenyl cyclase by cholera enterotoxin and prostaglandins. J Clin Invest. 1971;50:1218-1230.
20. Petritsch W, Eherer AJ, Holzer-Petsche U, Hinterleitner TA, Beubler E, Krejs GJ. Effect of cholera toxin on the human jejunum. 1992;33:1174-1178.
21. Jodal M, Holmgren S, Lundgren O, Sjoqvist A. Involvement of the myenteric plexus in the cholera toxin induced net fluid secretion in the rat small intestine. Gastroenterology. 1993;105:1286-1293.
22. Lundgren O, Jodal M. The enteric nervous system and cholera toxin-induced secretion. Comp Biochem Physiol. 1997;118A:319-329.
23. Goyal RK, Hirano 1. The enteric nervous system. N Engl J Med. 1996;334:1106-1115.
24. Brunsson I, Sjotlqvist A, Jodal M, Lundgren O. Mechanisms underlying the small intestinal fluid secretion caused by arachidonic acid, prostaglandin E1 and prostaglandin E2 in the rat in vivo. Acta Physiol Scand. 1987;130:633-642.
25. Pugin J, Schurer-Maly CC, Leturcq D, Moriarty A, Ulevitch RJ, Tobias PS. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc Natl Acad Sci USA. 1993;90:2744-2748.
26. Konturek PH. Involvement of nitric oxide and prostaglandin in gastroprotection induced by bacterial lipopolysacharide. Scand J Gastroenterol. 1998;33:691-700.
27. Izzo AA, Mascolo N, Capasso F. Nitric oxide as a modulator of intestinal water and electrolyte transport. Digest Dis Sci. 1998;43:1605-1620.
28. Greenwood-Van Meerveld B, Tyler K, Keith JC Jr. Recombinant human interleukin-11 modulates ion transport and mucosal inflammation in the small intestine and colon. Lab Invest. 2000;80:1269-1280.
29. Chiossone DC, Simon PL, Smith PL. Interleukin-1: effect on rabbit ileal mucosal ion transport in vitro. Eur J Pharmacol. 1990;180:217-228.
30. Theodorou V, Eutamene H, Fioramonti J, Junien JL, Bueno L. Interleukin-1 induces a neurally mediated colonic secretion in rats: involvement of mast cells and prostaglandins. Gastroenterology. 1994;106:1493-1500.
31. Madsen KL, Tavemini MM, Mosmann TR, Fedorak RN. Interleukin 10 modulates ion transport in rats small intestine. Gastroenterology. 1996;111:936-944.
32. Zund G, Madara JL, Dzus AL, Awtrey CS, Colgan SP. Interleukin-4 and Interleukin-13 differentially regulate epithelial chloride secretion. J Biol Chem. 1996;271:7460-7464.
33. Kawagoe H. Pharmacological studies on antidiarrheal effects of Hange-Shashin-To. J Clin Rehabil. 1994;3:1058-1059.
34. Kase Y, Hayakawa T, Takeda S, Ishige A, Aburada M, Okada M. Pharmacological studies on antidiarrheal effects of Hange-shashin-to. Biol Pharm Bull. 1996;19:1367-1370.
35. Kase Y, Hayakawa T, Takeda S, Ishige A, Aburada M, Okada M. Effects of Keishi-ka-shakuyaku-to (Gui-Zhi-Jia-Shao-Yao-Tang) on diarrhea and small intestinal movement. Biol Pharm Bull. 1998;22:87-89.
36. Gabriel SE, Davenport SE, Steagall RJ, Vimal V, Carlson T, Rozhon EJ. A novel plant-derived inhibitor of cAMP-mediated fluid and chloride secretion. Am J Physiol. 1999;276:G58-G63.