2 Chloro 2 deoxyadenosine; B CLL; CdA resistance; Cell cycle; G1 S transition; PRb
Indexed keywords
CLADRIBINE;
DEOXYCYTIDINE KINASE;
PROTEIN P21;
PROTEIN P53;
CELL CYCLE;
CELL CYCLE G1 PHASE;
CELL CYCLE S PHASE;
CONFERENCE PAPER;
CONTROLLED STUDY;
DNA SYNTHESIS;
DRUG MECHANISM;
DRUG METABOLISM;
ENZYME ACTIVITY;
HUMAN;
HUMAN CELL;
LEUKEMIA CELL;
PHASE TRANSITION;
PROTEIN INDUCTION;
PROTEIN METABOLISM;
PROTEIN PHOSPHORYLATION;
Effects of cytotoxicity of 2-chloro-2′-deoxyadenosine and 2-bromo-2′-deoxyadenosine on cell growth, clonogenicity, DNA synthesis, and cell cycle kinetics
Huang, M.C.; Ashmum, R.A.; Avery, T.L.; Kuehl, M.; Blackley, R.L. Effects of cytotoxicity of 2-chloro-2′-deoxyadenosine and 2-bromo-2′- deoxyadenosine on cell growth, clonogenicity, DNA synthesis, and cell cycle kinetics. Cancer Res. 1986, 46, 2362-2368.
Resistance to 2-chloro-2′-deoxyadenosine of the human B-cell leukemia cell line EHEB
Cardoen, S.; Van Den Neste, E.; Smal, C.; Rosier, J.F.; Delacauw, A.; Ferrant, A.; Van den Berghe, G.; Bontemps, F. Resistance to 2-chloro-2′- deoxyadenosine of the human B-cell leukemia cell line EHEB. Clin. Cancer Res. 2001, 7, 3559-3566.
Interaction of p53 and DNA-PK in response to nucleoside analogues: Potential role as a sensor complex for DNA damage
Achanta, G.; Pelicano, H.; Feng, L.; Plunkett, W.; Huang, P. Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage. Cancer Res. 2001, 16, 8723-8729.
S-phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine
Shi, Z.; Azuma, A.; Sampath, D.; Li, Y.X.; Huang, P.; Plunkett, W. S-phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine. Cancer Res. 2001, 61, 1065-1072.
The induction of p53 and WAF/CIP1 in chronic lymphocytic leukemia cells treated with 2-chlorodeoxyadenosine
Gartenhaus, R.B.; Wang, P.; Hoffman, M.; Janson, D.; Rai, K.R. The induction of p53 and WAF/CIP1 in chronic lymphocytic leukemia cells treated with 2-chlorodeoxyadenosine. J. Mol. Med. 1996, 74, 143-147.
Inhibition of cyclin-dependant kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: Dysregulation by 7-hydroxystaurosporine
Sampath, D.; Shi, Z.; Plunkett, W. Inhibition of cyclin-dependant kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine. Mol. Pharmacol. 2002, 62, 680-688.