The maturation-dependent production of interleukin-16 is impaired in monocyte-derived dendritic cells from atopic dermatitis patients but is restored by inflammatory cytokines TNF-α and IL-1β

Experimental Dermatology

Volumn 13, Issue 12, 2004, Pages 740-747

  Reich, Kristian ^a   Hugo, Sabine ^a   Middel, Peter ^a   Blaschke, Volker ^a   Heine, Andrea ^a   Neumann, Christine ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Allergy; Atopy; Chemokine; Cytokine; Dendritic cells

Indexed keywords

CD83 ANTIGEN; CD86 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 16; INTERLEUKIN 1BETA; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN EXPRESSION; ARTICLE; ATOPIC DERMATITIS; CELL DIFFERENTIATION; CELL MATURATION; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPATHOGENESIS; LEUKOCYTE ACTIVATION; LEUKOCYTE CULTURE; MONOCYTE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANTIGENS, CD; ANTIGENS, CD86; CELL DIFFERENTIATION; CELL MEMBRANE; CELL SEPARATION; CHEMOTAXIS; CYTOKINES; DENDRITIC CELLS; DERMATITIS, ATOPIC; DNA, COMPLEMENTARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-16; MEMBRANE GLYCOPROTEINS; MONOCYTES; PHENOTYPE; POLYMERASE CHAIN REACTION; RNA; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 10344240352     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2004.00251.x     Document Type: Article

References (29)

1. Center D M, Kornfeld H, Cruikshank W W. Interleukin 16 and its function as a CD4 ligand. Immunol Today 1996: 17: 476-481.
2. + T cells by IL-16 and IL-2. J Immunol 1998: 160: 2115-2120.
3. Hermann E, Darcissac E, Idziorek T, Capron A, Bahr G M. Recombinant interleukin-16 selectively modulates surface receptor expression and cytokine release in macrophages and dendritic cells. Immunology 1999: 97: 241-248.
4. Kaser A, Dunzendorfer S, Offner F A et al. A role for IL-16 in the cross-talk between dendritic cells and T cells. J Immunol 1999: 163: 3232-3238.
5. Baier M, Bannert N, Werner A, Lang K, Kurth R. Molecular cloning, sequence, expression, and processing of the interleukin 16 precursor. Proc Natl Acad Sci USA 1997: 94: 5273-5277.
6. Cruikshank W W, Long A, Tarpy R E et al. Early identification of interleukin-16 (lymphocyte chemoattractant factor) and macrophage inflammatory protein 1 alpha (MIP1 alpha) in bronchoalveolar lavage fluid of antigen-challenged asthmatics. Am J Respir Cell Mol Biol 1995: 13: 738-747.
7. Hessel E M, Cruikshank W W, Van A et al. Involvement of IL-16 in the induction of airway hyper-responsiveness and up-regulation of IgE in a murine model of allergic asthma. J Immunol 1998: 160: 2998-3005.
8. Laberge S, Pinsonneault S, Varga E M et al. Increased expression of IL-16 immunoreactivity in bronchial mucosa after segmental allergen challenge in patients with asthma. J Allergy Clin Immunol 2000: 106: 293-301.
9. + T-cell infiltration with increased IL-16 gene expression in atopic dermatitis. J Allergy Clin Immunol 1998: 102: 645-650.
10. Reich K, Hugo S, Middel P et al. Evidence for a role of Langerhans cell-derived IL-16 in atopic dermatitis. J Allergy Clin Immunol 2002: 109: 681-687.
11. Reich K, Heine A, Hugo S et al. Engagement of the Fc epsilon RI stimulates the production of IL-16 in Langerhans cell-like dendritic cells. J Immunol 2001: 167: 6321-6329.
12. Aiba S, Manome H, Yoshino Y, Tagami H. Alteration in the production of IL-10 and IL-12 and aberrant expression of CD23, CD83 and CD86 by monocytes or monocyte- derived dendritic cells from atopic dermatitis patients. Exp Dermatol 2003: 12: 86-95.
13. Wüthrich B, Schmid-Grendelmeier P. Definition and diagnosis of intrinsic versus extrinsic atopic dermatitis. In: Bieber T, Leung DYM, eds. Atopic dermatitis. New York: Marcel Dekker, 2002: 1-20.
14. + dendritic cells. Proc Natl Acad Sci USA 1996: 93: 2588-2592.
15. + peripheral blood monocytes. J Immunol 1996: 157: 3850-3859.
16. Romani N, Reider D, Heuer M et al. Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J Immunol Methods 1996: 196: 137-151.
17. Reddy A, Sapp M, Feldman M, Subklewe M, Bhardwaj N. A monocyte conditioned medium is more effective than defined cytokines in mediating the terminal maturation of human dendritic cells. Blood 1997: 90: 3640-3646.
18. Palucka K A, Taquet N, Sanchez-Chapuis F, Gluckman J C. Dendritic cells as the terminal stage of monocyte differentiation. J Immunol 1998: 160: 4587-4595.
19. + T lymphocyte chemoattractant factor, IL-16. J Immunol 1997: 159: 2904-2910.
20. Schluesener H J, Seid K, Kretzschmar J, Meyermann R. Leukocyte chemotactic factor, a natural ligand to CD4, is expressed by lymphocytes and microglial cells of the MS plaque. J Neurosci Res 1996: 44: 606-611.
21. Blaschke V, Reich K, Blaschke S, Zipprich S, Neumann C. Rapid quantitation of proinflammatory and chemoattractant cytokine expression in small tissue samples and monocyte-derived dendritic cells: validation of a new real-time RT-PCR technology. J Immunol Methods 2000: 246: 79-90.
22. Chupp G L, Wright E A, Wu D et al. Tissue and T cell distribution of precursor and mature IL-16. J Immunol 1998: 161: 3114-3119.
23. Junghans V, Gutgesell C, Jung T, Neumann C. Epidermal cytokines IL-1beta, TNF-alpha, and IL-12 in patients with atopic dermatitis: response to application of house dust mite antigens. J Invest Dermatol 1998: 111: 1184-1188.
24. Schuler G, Thurner B, Romani N. Dendritic cells: from ignored cells to major players in T-cell-mediated immunity. Int Arch Allergy Immunol 1997: 112: 317-322.
25. + dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation. J Immunol 1998: 161: 2804-2809.
26. Stumbles P A, Thomas J A, Pimm C L et al. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J Exp Med 1998: 188: 2019-2031.
27. Bellinghausen I, Brand U, Knop J, Saloga J. Comparison of allergen-stimulated dendritic cells from atopic and nonatopic donors dissecting their effect on autologous naïve and memory T helper cells of such donors. J Allergy Clin Immunol 2000: 105: 988-996.
28. van den Heuvel M M, Vanhee D D, Postmus P E, Hoefsmit E C, Beelen R H. Functional and phenotypic differences of monocyte-derived dendritic cells from allergic and nonallergic patients. J Allergy Clin Immunol 1998: 101:90-95.
29. Arrighi J F, Rebsamen M, Rousset F, Kindler V, Hauser C. A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by ipopolysaccharide, TNF-alpha, and contact sensitizers. J Immunol 2001: 166: 3837-3845.