Microcirculatory heterogeneity in the rat small intestine during compromised flow conditions

Microcirculation

Volumn 11, Issue 4, 2004, Pages 307-315

  Vajda, Kornél ^a   Szabó, Andrea ^b   Kucsa, Katalin ^b   Suki, Béla ^c   Boros, Mihály ^b  

^a 1st Department of Internal Medicine   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c Boston University   (United States)

Author keywords

Average red blood cell velocity; Heterogeneous microcirculation; Orthogonal Polarization spectral imaging technique

Indexed keywords

NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; CELL MOTION; CONTROLLED STUDY; ERYTHROCYTE COUNT; HEMORRHAGIC HYPOTENSION; HYPOVOLEMIA; IMAGING SYSTEM; INTESTINE BLOOD FLOW; INTESTINE ISCHEMIA; MALE; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; RESUSCITATION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SURVIVAL RATE;

ABDOMINAL MUSCLES; ANIMALS; ENDOTOXINS; ERYTHROCYTES; HEMORRHAGE; HYPOTENSION; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; MICROCIRCULATION; MICROSCOPY, VIDEO; MODELS, ANIMAL; NITRIC OXIDE; PERFUSION; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; TIME;

EID: 10244255222     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1080/10739680490437469     Document Type: Article

References (29)

1. Buell MG, Harding RK. (1989). Effects of peptide YY on intestinal blood flow distribution and motility in the dog. Regul Pept 24:195-208.
2. Cassuto J, Cedgard S, Haglund U, Redfors S, Lundgren O. (1979). Intramural blood flows and flow distribution in the feline small intestine during arterial hypotension. Acta Physiol Scand 106:335-342.
3. Chou CC, Alemayehu A. (1993). Peptidergic regulation of gastrointestinal blood flow. In: Handbook of Experimental Pharmacology Vol. 106, Gastrointestinal Regulatory Peptides (DR Brown, Ed.) Berlin: Springer-Verlag, 225-342.
4. Colantuoni A, Bertuglia S, Intaglietta M. (1985). Microvessel diameter changes during hemorrhagic shock in unanesthetized hamsters. Microvasc Res 30:133-142.
5. Connolly HV, Maginniss LA, Schumacker PT, (1997). Transit time heterogeneity in canine small intestine: significance for oxygen transport. J Clin Invest 99:228-238.
6. Cousineau DF, Goresky CA, Rose CP, Simard A, Schwab AJ. (1995). Effects of flow, perfusion pressure, and oxygen consumption on cardiac capillary exchange. J Appl Physiol 78:1350-1359.
7. Damber JE, Lindahl O, Selstam G, Tenland T. (1982). Testicular blood flow measured with a laser Doppler flowmeter: acute effects of catecholamines. Acta Physiol Scand 115:209-215.
8. Fink MP, Cohn SM, Lee PC. Rothschild HR, Deniz YF, Wang H. (1989). Effect of lipopolysaccharide on intestinal intramucosal hydrogen ion concentration in pigs: evidence of gut ischemia in a normodynamic model of septic shock. Crit Care Med 17:641-646.
9. Friesenecker B, Tsai AG, Intaglietta M. (1994). Capillary perfusion during ischemia-reperfusion in subcutaneous connective tissue and skin muscle. Am J Physiol 267:H2204-2212.
10. Gore RW, Bohlen HG. (1977). Microvascular pressures in rat intestinal muscle and mucosal villi. Am J Physiol 233:H685-H693.
11. Groner W, Winkelman JW, Harris AG, Ince C, Bouma GJ, Messmer K, Nadeau RG. (1999). Orthogonal polarization spectral imaging: a new method for study of the microcirculation. Nat Med 5:1209-1212.
12. Gustafsson H, Nilsson H. (1993). Rhythmic contractions of isolated small arteries from rat: influence of endothelium. Acta Physiol Scand 148:153-163.
13. Heuser M, Gralla O, Pfaar O, Nustede R, Grone HJ, Post S. (2000). Differential effects of neurotensin and cholecystokinin on intestinal microcirculation after ischemia-reperfusion. Langenbecks Arch Surg 385:357-362.
14. Landow L, Andersen LW. (1994). Splanchnic ischaemia and its role in multiple organ failure. Acta Anaesthesiol Scand 38:626-639.
15. Lossius K, Eriksen M. (1999). Spontaneous flow waves detected by laser Doppler in human skin. Microvasc Res 50:94-104.
16. Madorin WS, Martin CM, Sibbald WJ. (1999). Dopexamine attenuates flow motion in ileal mucosal arterioles in normotensive sepsis. Crit Care Med 27:394-400.
17. Matheson PJ, Wilson MA, Garrison RN. (2000). Regulation of intestinal blood flow. J Surg Res 93:182-196.
18. Pittner A, Nalos M, Asfar P, Yang Y, Ince C, Georgieff M, Bruckner UB, Radermacher P, Froba G. (2003). Mechanisms of inducible nitric oxide synthase (iNOS) inhibition-related improvement of gut mucosal acidosis during hyperdynamic porcine endotoxemia. Intensive Care Med 29:312-316.
19. Rucker M, Strobel O, Vollmar B, Roesken F, Menger MD. (2000). Vasomotion in critically perfused muscle protects adjacent tissues from capillary perfusion failure. Am J Physiol 279:H550-558.
20. Schmidt H, Secchi A, Wellmann R, Bach A, Bohrer H, Gebhard MM, Martin E. (1996). Effect of endotoxemia on intestinal Villus microcirculation in rats. J Surg Res 61:521-526.
21. Spain DA, Wilson MA, Krysztopik RJ, Matheson PJ, Garrison RN. (1997). Differential intestinal microvascular dysfunction occurs during bacteremia. J Surg Res 67:67-71.
22. Theuer CJ, Wilson MA, Steeb GD, Garrison RN. (1993). Microvascular vasoconstriction and mucosal hypoperfusion of the rat small intestine during bacteremia. Circ Shock 40:61-68.
23. Tokyay R, Zeigler ST, Traber DL, Stothert JC Jr, Loick HM. (1993). Postburn gastrointestinal vasoconstriction increases bacterial and endotoxin translocation. J Appl Physiol 74:1521-1527.
24. Tsai AG, Friesenecker B, Intaglietta M. (1995). Capillary flow impairment and functional capillary density. Int J Microcirc Clin Exp 15:238-243.
25. Tyml K, Mikulash K. (1988). Evidence for increased perfusion heterogeneity in skeletal muscle during reduced flow. Microvasc Res 35:316-324.
26. 2 in endotoxemic dogs during shock and resuscitation. J Appl Physiol 76:793-800.
27. Vollmar B, Preissler G, Menger MD. (1994). Hemorrhagic hytension induces arteriolar vasomotion and intermittent capillary perfusion in rat pancreas. Am J Physiol 267:H1936-H1940.
28. Whitworth PW, Cryer HM, Garrison RN, Baumgarten TE, Harris PD. (1989). Hypoperfusion of the intestinal microcirculation without decreased cardiac output during live Escherichia coli sepsis in rats. Circ Shock 27:111-122.
29. Xu D, Qi L, Guillory D, Cruz N, Berg R, Deitch EA. (1993). Mechanisms of endotoxin-induced intestinal injury in a hyperdynamic model of sepsis. J Trauma 34:676-682.