TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines

Blood

Volumn 88, Issue 3, 1996, Pages 785-794

  Kim, Do Hyun ^b   Moldwin, Richard L ^b   Vignon, Christine ^b   Bohlander, Stefan K ^b   Suto, Yoshimasa ^b   Giordano, Lisa ^b   Gupta, Rajat ^b   Fears, Scott ^b   Nucifora, Giuseppina ^b   Rowley, Janet D ^b   Smith, Stephen D ^a  

^a UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN P16;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CHILD; CHROMOSOME TRANSLOCATION 12; CLINICAL ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; HUMAN; HUMAN CELL; KARYOTYPE; LEUKEMIA CELL LINE; MALE; NORTHERN BLOTTING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 10144250286     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.3.785.785     Document Type: Article

References (42)

1. Raimondi SC, Williams DL, Callihan T, Peiper S, Rivera GK, Murphy SB: Nonrandom involvement of the 12p12 breakpoint in chromosome abnormalities of childhood acute lymphoblastic leukemia. Blood 68:69, 1986
2. Takeuchi S, Bartram CR, Wada M, Reiter A, Hatta Y, Seriu T, Lee E, Miller CW, Miyoshi I, Koeffler HP: Allelotype analysis of childhood acute lymphoblastic leukemia. Cancer Res 55:5377, 1995
3. KIP1 [sic]. Blood 86:3869, 1995
4. Stegmaier K, Pendse S, Barker GF, Bray-Ward P, Ward DC, Montgomery KT, Krauter KS, Reynolds C, Sklar J, Donnelly M, Bohlander SK, Rowley JD, Sallan SE, Gilliland DG, Golub TR: Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood. Blood 86:38, 1995
5. Sato Y, Suto Y, Pietenpol J, Golub TR, Gilliland DG, Davis EM, Le Beau MM, Roberts JM, Vogelstein B, Rowley JD, Bohlander SK: TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietie malignancies. Blood 86:1525, 1995
6. Golub TR, Barker GF, Lovett M, Gilliland DG: Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 77:307, 1994
7. Golub TR, Barker GF, Bohlander SK, Hiebert SW, Ward DC, Bray-Ward P, Morgan E, Raimondi SC, Rowley JD, Gilliland DG: Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proc Nat Acad Sci USA 92:4917, 1995
8. Janssen JW, Ridge SA, Papadopoulos P, Cotter F, Ludwig WD, Fonatsch C, Rieder H, Ostertag W, Bartram CR, Wiedemann LM: The fusion of TEL and ABL in human acute lymphoblastic leukaemia is a rare event. Br J Haematol 90:222, 1995
9. Buijs A, Sherr S, van Baal S, van Bezouw S, van der Plas D, van Kessel GA, Riegman P, Deprez RL, Zwarthoff E, Hagemeijer A, Grosveld G: Translocation (12;22)(p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. Oncogene 10:1511, 1995
10. Papadopoulos P, Ridge SA, Boucher CA, Stocking C, Wiedemann LM: The novel activation of ABL by fusion to an ets-related gene, TEL. Cancer Res 55:34, 1995
11. Romana SP, Mauchauffe M, Le Coniat M, Chumakov I, Le Paslier D, Berger R, Bernard OA: The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion. Blood 85:3662, 1995
12. Kobayashi H, Montgomery KT, Bohlander SK, Adra CN, Lim BL, Kucherlapati RS, Donis-Keller H, Holt MS, Le Beau MM, Rowley JD: Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases. Blood 84:3473, 1994
13. Romana SP, Le Coniat M, Berger R: t(12;21): A new recurrent translocation in acute lymphoblastic leukemia. Genes Chromosomes Cancer 9:186, 1994
14. Romana SP, Poirel H, Leconiat M, Flexor M-A, Mauchauffe M, Jonveaux P, Macintyre EA, Berger R, Bernard OA: High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia. Blood 86:4263, 1995
15. Shurtleff SA, Buijs A, Behm FG, Rubnitz JE, Raimondi SC, Hancock ML, Chan GC-F, Pui C-H, Grosveld G, Downing JR: TEL/ AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia 9:1985, 1995
16. INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias. Blood 84:4038, 1994
17. Takeuchi S, Bartram CR, Seriu T, Miller CW, Tobler A, Janssen JW, Reiter A, Ludwig W-D, Zimmermann M, Schwaller J, Lee E, Miyoshi I, Koeffler HP: Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood. Blood 86:755, 1995
18. Cayuela J-M, Madani A, Sanhes L, Stern M-H, Sigaux F: Multiple tumor-suppressor gene 1 inactivation is the most frequent genetic alteration in T-cell acute lymphoblastic leukemia. Blood 87:2180, 1996
19. Serrano M, Hannon GJ, Beach D: A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704, 1993
20. Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA: Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 368:753, 1994
21. Jagasia AA, Sher DA, Le Moine PJ, Kim D-H, Moldwin RL, Smith SD, Diaz MO: Deletion or lack of expression of CDKN2 (CDK4I/MTS1/INK4A) and MTS2 (INK4B) in acute lymphoblastic leukemia cell lines reflects the phenotype of the uncultured primary leukemia cells. Leukemia 10:624, 1996
22. Rowley JD, Diaz MO, Espinosa R III, Patel YD, van Melle E, Ziemin S, Taillon-Miller P, Lichter P, Evans GA, Kersey JH, Ward DC, Domer PH, Le Beau MM: Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: Identification of 11q23 translocation breakpoints with a yeast artificial chromosome. Proc Nat Acad Sci USA 87:9358, 1990
23. Bohlander SK, Espinosa R III, Fernald AA, Rowley JD, Le Beau MM, Diaz MO: Sequence-independent amplification of yeast artificial chromosomes for fluorescent in situ hybridization. Cytogenet Cell Genet 65:108, 1994
24. Miyoshi H, Ohira M, Shimizu K, Mitani K, Hirai H, Imai T, Yokoyama K, Soeda E, Ohki M: Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia. Nucleic Acids Res 23:2762, 1995
25. Suto Y, Sato Y, Smith SD, Rowley JD, Bohlander SK: TEL is fused to a previously unknown gene, STL, in a t(6;12)(q23;p13) translocation in a patient with acute lymphoblastic leukemia. Ann Hematol 70:A117, 1995 (abstr)
26. Venaut A-M, Testu M-J, Rosenfeld C: Cytogentic abnormalities in a human null cell leukemia line. Cancer Genet Cytogenet 3:327, 1981
27. Zhang LQ, Downie PA, Goodell WR, McCabe NR, Le Beau MM, Morgan R, Sklar J, Raimondi SC, Miley D, Goldberg A, Lu M-M, Montag A, Smith SD: Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia. Leukemia 7:1865, 1993
28. Rosenfeld C, Goutner A, Choquet C, Venaut AM, Kayibanda B, Pico JL: Phenotypic characterisation of a unique non-T, non-B acute lymphoblastic leukemia cell line. Nature 267:841, 1977
29. Raynaud S, Cave H, Baens M, Bastard C, Cacheux V, Grosgeorge J, Guidal-Giroux C, Guo C, Vilmer E, Marynen P, Grandchamp B: The 12;21 translocation involving TEL and deletion of the other TEL allele: Two frequently associated alterations found in childhood acute lymphoblastic leukemia. Blood 87:2891, 1996
30. Romana SP, Le Coniat M, Poirel H, Marynen P, Bernard OA, Berger R: Deletion of the short arm of chromosome 12 is a secondary event in acute lymphoblastic leukemia with t(12;21). Leukemia 10:167, 1996
31. Stegmaier K, Takeuchi S, Golub TR, Bohlander SK, Bartram CR, Koeffler HP, Gilliland DG: Mutation analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia. Cancer Res 56:1413, 1996
32. Cho KR, Vogelstein B: Genetic alterations in the adenomacarcinoma sequence [review]. Cancer 70:1727, 1992
33. Goyette MC, Cho K, Fasching CL, Levy DB, Kinzler KW, Paraskeva C, Vogelstein B, Stanbridge EJ: Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer. Molec Cell Biol 12:1387, 1992
34. Pandrau D, Frances V, Martinez-Valdez H, Pages M-P, Manel A-M, Philippe N, Banchereau J, Saeland S: Characterization of a t(1;19) pre-B acute lymphoblastic leukemia (ALL) cell line which proliferates in response to IL-7. Leukemia 7:635, 1993
35. Nourse J, Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD, Cleary ML: Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 60:535, 1990
36. Smith SD, Morgan R, Galili N, Amylon MD, Link MP, Hecht F, Sklar J, Glader BE: Establishment and characterization of a common acute lymphoblastic leukemia cell line with a deletion of chromosome 3 band q26. Cancer Res 47:1652, 1987
37. Findley HW, Cooper MD, Kim TH, Alvarado C, Ragab AH: Two new acute lymphoblastic leukemia cell lines with early B-cell phenotypes. Blood 60:1305, 1982
38. Barker PE, Carroll AJ, Cooper MD: t(1;19)(q23;p13) in pre-B acute lymphoblastic leukemia line 697. Cancer Genet Cytogenet 25:379, 1987
39. Jack I, Seshadri R, Garson M, Michael P, Callen D, Zola H, Morley A: RCH-ACV: A lymphoblastic leukemia cell line with chromosome translocation 1;19 and trisomy 8. Cancer Genet Cytogenet 19:261, 1986
40. Naumovski L, Morgan R, Hecht F, Link MP, Glader BE, Smith SD: Philadelphia chromosome-positive acute lymphoblastic leukemia cell lines without classical breakpoint cluster region rearrangement. Cancer Res 48:2876, 1988
41. Lorenzana AN, McCabe NR, Goodell WR, Zhang LQ, Miley D, Le Beau MM, Goldman S, Smith SD: Characterization of a CD34+ cell line established from a child with large cell cutaneous lymphoma. Cancer 72:931, 1993
42. Downie PA, Vogelzang NJ, Moldwin RL, Le Beau MM, Anastasi J, Allen RJ, Myers SE, Larson RA, Smith SD: Establishment of a leukemia cell line with i(12p) from a patient with a mediastinal germ cell tumor and acute lymphoblastic leukemia. Cancer Res 54:4999, 1994