Atypical forms of multiple sclerosis or different phases of a same disease?

Neurological Sciences

Volumn 25, Issue SUPPL. 4, 2004, Pages

  Trojano, M ^a   Paolicelli, D ^a   Bellacosa, A ^a   Fuiani, A ^a   Cataldi, S ^a   Di Monte, E ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Age; Age at onset; Disability progression; Disease course; Multiple sclerosis

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DISEASE COURSE; DISEASE DURATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; ONSET AGE; PHENOTYPIC VARIATION; RECURRENCE RISK; SEX DIFFERENCE;

ADOLESCENT; ADULT; AGE FACTORS; AGE OF ONSET; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; DEMYELINATING DISEASES; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 10044255662     PISSN: 15901874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10072-004-0334-0     Document Type: Article

References (14)

1. Lublin FD, Reingold SC (1996) Defining the clinical course of multiple sclerosis: Results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple sclerosis. Neurology 6(4):907-911
2. Duquette P, Murray TJ, Pleines J et al (1987) Multiple sclerosis in childhood: Clinical profile in 125 patients. J Pediatr 111(3):359-363
3. Ruggieri M, Polizzi A, Pavonel, Grimaldi LM (1999) Multiple sclerosis in children under 6 years of age. Neurology 53:478-484
4. Ghezzi A, Deplano V, Faroni J et al (1997) Multiple Sclerosis in childhood: Clinical features of 149 cases. Mult Scler 3:43-46
5. Simone IL, Carrara D, Tortorella C et al (2002) Course and prognosis of early onset MS: Comparison with adult-onset forms. Neurology 59:1922-1928
6. Trojano M, Liguori M, Zimatore GB (2002) Age-related disability in multiple sclerosis. Ann Neurol 51:475-480
7. Waxman SG (1998) Demyelinating diseases-new pathological insights, new therapeutic targets. N Engl J Med 338:223-225
8. Bjartmar C, Trapp BD (2001) Axonal and neuronal degeneration in multiple sclerosis: Mechanisms and functional consequences. Curr Opin Neurol 14:271-278
9. Reddy H, Narayanan S, Arnoutelis R et al (2000) Evidence for adaptive functional changes in the cerebral cortex with axonal injury from multiple sclerosis. Brain 123:2314-2320
10. Trapp BD, Peterson J, Ransohoff RM et al (1998) Axonal transection in the lesions of multiple sclerosis. N Engl J Med 338:278-285
11. Bjartmar C, Kidd G, Mork S et al (2000) Neurological disability correlates with spinal cord axonal loss and reduced Nacetyl aspartate in chronic multiple sclerosis patients. Ann Neurol 48:893-901
12. De Stefano N, Matthews PM, Fu L et al (1998) Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study. Brain 121:1469-1477
13. Fu L, Matthews PM, De Stefano N (1998) Imaging axonal damage of normal-appearing white matter in multiple sclerosis. Brain 121:103-113
14. Trapp BD, Ransohoff RM, Fisher E, Rudick RA (1999) Neurodegeneration in multiple sclerosis: Relationship to neurological disability. Neuro-scientist 5:48-57