A nonviral carrier for targeted gene delivery to tumor cells

Cancer Gene Therapy

Volumn 11, Issue 2, 2004, Pages 156-164

  Van Zanten, Jacoba ^a   Van Der Meer, Berber Doornbos ^a   Audouy, Sandrine ^b   Kok, Robbert Jan ^b   De Leij, Lou ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Department of Membrane Cell Biology ^*  (Netherlands)

Author keywords

Cationic lipid; DNA carrier; Monoclonal antibodies; SAINT DOPE; Tumor cells

Indexed keywords

DIOLEOYLPHOSPHATIDYLCHOLINE; EPITHELIAL GLYCOPROTEIN 2; GLYCOPROTEIN; IMMUNOGLOBULIN F(AB')2 FRAGMENT; LIPID; LIPID BINDING PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MOC31; N METHYL 4 (DIOLEOYL)METHYLPYRIDINIUM CHLORIDE; PLASMID DNA; PYRIDINIUM DERIVATIVE; TRASTUZUMAB; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; COVALENT BOND; DNA PACKAGING; ENDOSOME; GENE EXPRESSION REGULATION; GENE TARGETING; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TARGET CELL; TUMOR CELL; VIRUS CARRIER;

ANIMALS; ANTIBODIES, MONOCLONAL; CATIONS; CELL LINE, TUMOR; DNA; GENE TARGETING; GENE THERAPY; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; LIPID METABOLISM; LIPOSOMES; MELANOMA; MICE; NEOPLASMS; PHOSPHATIDYLETHANOLAMINES; PLASMIDS; SKIN NEOPLASMS; TRANSFECTION;

ANIMALIA;

EID: 0942279603     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700668     Document Type: Article

References (31)

1. Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome. Science. 1995;291:1304-1351.
2. Miller AD. Retrovirus packaging cells. Human Gene Ther. 1990;1(1):5-14.
3. Mah C, Byrne BJ, Flotte TR. Virus-based gene delivery systems. Clin Pharmocokinet. 2002;41:901-91.
4. Schiedner G, Morral N, Parks RJ, el al. Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nat Genet. 1998;18:180-183.
5. Carter PJ, Samulski RJ. Adeno-associated viral vectors as gene delivery vehicles. Int J Mol Med. 2000;6:17-27.
6. Kay MA, Manno CS, Ragni MV. Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector. Nat Genet. 2000;24:257-261.
7. Cristiano RJ. Protein/DNA polyplexes for gene therapy. Surg Oncol Clin N Am. 2002;11:697-716.
8. Dunlap DD, Maggi AS, Marco R, Monaco L. Nanoscopic structure of DNA condensed for gene delivery. Nucl Acid Res. 1997;25:3095-3101.
9. Ferkol T, Perales JC, Eckman, E, et al. Gene transfer into the airway epithelium of animals by targeting the polymeric immunogobulin receptor. J Clin Invest. 1995;95:493-502.
10. Nishikawa M, Yamauchi M, Morimoto K, Ishida E, et al. Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multifunctional gene delivery system. Gene therapy. 2000;7:548-555.
11. Kircheis R, Kichler A, Wallner G, et al. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery. Gene Therapy. 1997;4:409-418.
12. Li S, Rizzo MA, Bhattacharaya S, Huang L. Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery. Gene Therapy. 1998;5:930-937.
13. Felgner PL, Gadek TR, Holm M, Roman R, et al. Lipofection: a highly efficient, lipid mediated DNA transfection procedure. Proc Natl Acad Sci USA. 1987;84:7413-7417.
14. Smyth Templeton N, Lasic DD, Frederik PM, et al. Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nat Biotechnol. 1997;15:647-652.
15. Liu Y, Thor A, Shtivelman E, et al. Systemic gene delivery expands the repertoire of effective antiangiogenic agents. J Biol Chem. 1999; 274:13338-13344.
16. Vd Woude I, Wagenaar A, Meekel AP, et al. Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery. Proc Natl Acad Sci. 1997;94:1160-1165.
17. Audouy S, Molema G, de Leij L, Hoekstra D. Serum as a modulator of lipoplex-mediated gene transfection: dependance of amphiphile, cell type and complex stability. J Gene Med. 2000;2:465-476.
18. Zuhorn IS, Oberle V, Visser W, Engberts JBFN, Bakowsky U, Hoekstra D. The phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency. Biophys J. 2002;83(4):2096-2108.
19. Li S, Tan Y, Viroonchatapan E, et al. Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody. Am J Physiol Lung Cell Mol Phys. 2000;278:504-511.
20. Spragg DD, Alford DR, Greferath R, et al. Immunotargeting of liposomes to activated vascular endothelial cells: a strategy for site-selective delivery in the cardiovascular system. Proc Natl Acad Sci USA. 1997;94:8795-8800.
21. Mastrobattista E, Kapel RHG, Eggenhuisen MH, et al. Lipid-coated polyplexes for targeted gene delivery to ovarian carcinoma cells. Cancer Gene Ther. 2001;8(6): 405-413.
22. Xu L, Tang W-H, Huang C-C, et al. Systemic p53 gene therapy of cancer with immunolipoplexes targeted by antitransferrin receptor scFv. Mol Med. 2001;7(10):723-734.
23. Balzar M, Winter MJ, de Boer CJ, Litvinov S. The biology of the 17-1A antigen (Ep-CAM). J Mol Med. 1999;77: 699-712.
24. Herlyn M, Steplewski Z, Herlyn D, Koprowski H. Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies. Proc Natl Acad Sci USA. 1979;76:1438-1452.
25. Semba K, Kamata N, Toyoshima K, Yamamoto T. A v-erbB-related protooncogene, c-erbB2, is distinct from the c-erb-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc Natl Acad Sci USA. 1985;82:6497.
26. Carter P, Presta L, Gorman C, et al. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci USA. 1992;89:4285-4290.
27. Sliwkowski MX, Lofgren JA, Lewis GD, Hotaling TE, Fendly BM, Fox JA. Nonclinical studies addressing the mechanism of action of Trastuzumab (Herceptin). Seminars in Oncol. 1999;26(4):60-70.
28. Mariani M, Camagna M, Tarditi L, Seccamini E. A new anzymatic method to obtain high yield F(ab)2 suitable for clinical use from mouse IgG1. Mol Immunol. 1991; 28(1/2):69-77.
29. De Jonge MW, Kosterink JGW, Bin YY, et al. Radio-immunodetection of human small cell lung carcinoma xenografts in the nude rat using 111 in-labelled monoclonal antibody MOC31. Eur J Cancer. 1993;29A(13):1885-1890.
30. Ross PC, Hui HW. Lipoplex size is a major determinant of in vitro lipofection efficiency. Gene Therapy. 1999;6:651-659.
31. Audouy S, Hoekstra D, de Leij L, Hospers G, Molema G. Behaviour of SAINT lipoplexes after intravenous administration: safety and biodistribution in mice. Thesis, Cationic liposomes as DNA delivery system. 2002; Chapter 5, p. 87-101.