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Volumn 314, Issue 4, 2004, Pages 971-975

Deletion of the cytoplasmic domain increases basal shedding of angiotensin-converting enzyme

Author keywords

ACE; Actin cytoskeleton; CHO; Cytochalasin D; Cytoplasmic domain; Ectodomain shedding

Indexed keywords

CYTOCHALASIN D; DIPEPTIDYL CARBOXYPEPTIDASE; MEMBRANE PROTEIN; MUTANT PROTEIN; PHORBOL ESTER; PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA PROTEASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0942278964     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.12.198     Document Type: Article
Times cited : (6)

References (15)
  • 1
    • 0032921863 scopus 로고    scopus 로고
    • The cytoplasmic carboxy-terminal amino acid determines the subcellular localization of proTGF-(alpha) and membrane type matrix metalloprotease (MT1-MMP)
    • Urena J.M., Merlos-Suarez A., Baselga J., Arribas J. The cytoplasmic carboxy-terminal amino acid determines the subcellular localization of proTGF-(alpha) and membrane type matrix metalloprotease (MT1-MMP). J. Cell Sci. 112:1999;773-784.
    • (1999) J. Cell Sci. , vol.112 , pp. 773-784
    • Urena, J.M.1    Merlos-Suarez, A.2    Baselga, J.3    Arribas, J.4
  • 2
    • 0037031551 scopus 로고    scopus 로고
    • A structural mechanism of integrin alpha(IIb)beta(3) "inside- out" activation as regulated by its cytoplasmic face
    • Vinogradova O., Velyvis A., Velyviene A., Hu B., Haas T., Plow E., Qin J. A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face. Cell. 110:2002;587-597.
    • (2002) Cell , vol.110 , pp. 587-597
    • Vinogradova, O.1    Velyvis, A.2    Velyviene, A.3    Hu, B.4    Haas, T.5    Plow, E.6    Qin, J.7
  • 3
    • 0032563098 scopus 로고    scopus 로고
    • A basic amino acid in the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein (APP) is essential for cleavage of APP at the alpha-site
    • Tomita S., Kirino Y., Suzuki T. A basic amino acid in the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein (APP) is essential for cleavage of APP at the alpha-site. J. Biol. Chem. 273:1998;19304-19310.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19304-19310
    • Tomita, S.1    Kirino, Y.2    Suzuki, T.3
  • 4
    • 0035022249 scopus 로고    scopus 로고
    • Shedding of growth hormone-binding protein is inhibited by hydroxamic acid-based protease inhibitors: Proposed mechanism of activation of growth hormone-binding protein secretase
    • Amit, T., Amit, T., Hochberg Z., Yogev-Falach M., Youdim M.B., Youdim M.B., Barkey R.J. Shedding of growth hormone-binding protein is inhibited by hydroxamic acid-based protease inhibitors: proposed mechanism of activation of growth hormone-binding protein secretase. J. Endocrinol. 169:2001;397-407.
    • (2001) J. Endocrinol. , vol.169 , pp. 397-407
    • Amit, T.1    Amit, T.2    Hochberg, Z.3    Yogev-Falach, M.4    Youdim, M.B.5    Youdim, M.B.6    Barkey, R.J.7
  • 6
    • 0028588080 scopus 로고
    • Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor
    • Brakebusch C., Varfolomeev E.E., Batkin M., Wallach D. Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor. J. Biol. Chem. 269:1994;32488-32496.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32488-32496
    • Brakebusch, C.1    Varfolomeev, E.E.2    Batkin, M.3    Wallach, D.4
  • 7
    • 0028147202 scopus 로고
    • Transmembrane kit ligand cleavage does not require a signal in the cytoplasmic domain and occurs at a site dependent on spacing from the membrane
    • Cheng H.J., Flanagan J.G. Transmembrane kit ligand cleavage does not require a signal in the cytoplasmic domain and occurs at a site dependent on spacing from the membrane. Mol. Biol. Cell. 5:1994;943-953.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 943-953
    • Cheng, H.J.1    Flanagan, J.G.2
  • 8
    • 0034194191 scopus 로고    scopus 로고
    • Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sites
    • Woodman Z.L., Oppong S.Y., Cook S., Hooper N.M., Schwager S.L., Brandt W.F., Ehlers M.R., Sturrock E.D. Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sites. Biochem. J. 347:2000;711-718.
    • (2000) Biochem. J. , vol.347 , pp. 711-718
    • Woodman, Z.L.1    Oppong, S.Y.2    Cook, S.3    Hooper, N.M.4    Schwager, S.L.5    Brandt, W.F.6    Ehlers, M.R.7    Sturrock, E.D.8
  • 9
    • 13144250144 scopus 로고    scopus 로고
    • The distal ectodomain of angiotensin-converting enzyme regulates its cleavage-secretion from the cell surface
    • Sadhukhan R., Sen G.C., Ramchandran R., Sen I. The distal ectodomain of angiotensin-converting enzyme regulates its cleavage-secretion from the cell surface. Proc. Natl. Acad. Sci. USA. 95:1998;138-143.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 138-143
    • Sadhukhan, R.1    Sen, G.C.2    Ramchandran, R.3    Sen, I.4
  • 10
    • 0029775898 scopus 로고    scopus 로고
    • Proteolytic release of membrane-bound angiotensin-converting enzyme: Role of the juxtamembrane stalk sequence
    • Ehlers M.R., Schwager S.L., Scholle R.R., Manji G.A., Brandt W.F., Riordan J.F. Proteolytic release of membrane-bound angiotensin-converting enzyme: role of the juxtamembrane stalk sequence. Biochemistry. 35:1996;9549-9559.
    • (1996) Biochemistry , vol.35 , pp. 9549-9559
    • Ehlers, M.R.1    Schwager, S.L.2    Scholle, R.R.3    Manji, G.A.4    Brandt, W.F.5    Riordan, J.F.6
  • 11
    • 0025973162 scopus 로고
    • Spontaneous solubilization of membrane-bound human testis angiotensin-converting enzyme expressed in Chinese hamster ovary cells
    • Ehlers M.R., Chen Y.N., Riordan J.F. Spontaneous solubilization of membrane-bound human testis angiotensin-converting enzyme expressed in Chinese hamster ovary cells. Proc. Natl. Acad. Sci. USA. 88:1991;1009-1013.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1009-1013
    • Ehlers, M.R.1    Chen, Y.N.2    Riordan, J.F.3
  • 12
    • 0033543135 scopus 로고    scopus 로고
    • Modulation of juxtamembrane cleavage (shedding) of angiotensin- converting enzyme by stalk glycosylation: Evidence for an alternative shedding protease
    • Schwager S.L., Chubb A.J., Scholle R.R., Brandt W.F., Mentele R., Riordan J.F., Sturrock E.D., Ehlers M.R. Modulation of juxtamembrane cleavage (shedding) of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease. Biochemistry. 38:1999;10388-10397.
    • (1999) Biochemistry , vol.38 , pp. 10388-10397
    • Schwager, S.L.1    Chubb, A.J.2    Scholle, R.R.3    Brandt, W.F.4    Mentele, R.5    Riordan, J.F.6    Sturrock, E.D.7    Ehlers, M.R.8
  • 15
    • 0034725601 scopus 로고    scopus 로고
    • Specific cellular proteins associate with angiotensin-converting enzyme and regulate its intracellular transport and cleavage-secretion
    • Santhamma K.R., Sen I. Specific cellular proteins associate with angiotensin-converting enzyme and regulate its intracellular transport and cleavage-secretion. J. Biol. Chem. 275:2000;23253-23258.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23253-23258
    • Santhamma, K.R.1    Sen, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.