Ultrasound to Stimulate Mandibular Bone Defect Healing: A Placebo-Controlled Single-Blind Study in Rats

Journal of Oral and Maxillofacial Surgery

Volumn 62, Issue 2, 2004, Pages 194-201

  Schortinghuis, Jurjen ^a,b   Ruben, Jan L ^a   Raghoebar, Gerry M ^a   Stegenga, Boudewijn ^a  

^a Dept of Oral/Maxillofacial Surg ^*

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO;

ADOLESCENT; ANIMAL MODEL; ARTICLE; BONE DEFECT; BONE RADIOGRAPHY; CONTROLLED STUDY; FRACTURE HEALING; MALE; MANDIBLE; MANDIBLE DEFECT; MANDIBLE DEFECT HEALING; MICRORADIOGRAPHY; NONHUMAN; RAT; SINGLE BLIND PROCEDURE; STIMULATION; ULTRASOUND THERAPY;

EID: 0942276335     PISSN: 02782391     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joms.2003.06.006     Document Type: Article

References (41)

1. Schmitz JP, Schwartz Z, Hollinger O, et al: Characterization of rat calvarial nonunion defects. Acta Anat 138:185, 1990
2. Tong L, Buchman SR: Facial bone grafts: Contemporary science and thought. J Craniomaxillofac Trauma 6:31, 2000
3. Dahlin C, Andersson L, Linde A: Bone augmentation at fenestrated implants by an osteopromotive membrane technique. A controlled clinical study. Clin Oral Implant Res 2:159, 1991
4. Dahlin C, Lekholm U, Becker W, et al: Treatment of fenestration and dehiscence bone defects around oral implants using the guided tissue regeneration technique: A prospective multicenter study. Int J Oral Maxillofac Implants 10:312, 1995
5. Heckman JD, Ryaby JP, McCabe J, et al: Acceleration of tibial fracture-healing by non-invasive, low-intensity pulsed ultrasound. Am J Bone Joint Surg 76:26, 1994
6. Kristiansen TK, Ryaby JP, McCabe J, et al: Accelerated healing of distal radial fractures with the use of specific, low-intensity ultrasound. A multicenter, prospective, randomized, double-blind, placebo-controlled study. Am J Bone Joint Surg 79:961, 1997
7. Nolte PA, van der Krans A, Patka P, et al: Low-intensity pulsed ultrasound in the treatment of nonunions. J Trauma 51:693, 2001
8. Frankel VH, Mizuno H: Surgical Technology X. San Francisco, CA, University Medical Press, 2001, p 195
9. Mayr E, Laule A, Suger G, et al: Radiographic results of callus distraction aided by pulsed low-intensity ultrasound. J Orthop Trauma 15:407, 2001
10. Sato W, Matsushita T, Nakamura K: Acceleration of increase in bone mineral content by low-intensity ultrasound in leg lengthening. J Ultrasound Med 18:699, 1999
11. Yang KH, Park SJ: Stimulation of fracture healing in a canine ulna full-defect model by low-intensity pulsed ultrasound. Yonsei Med J 42:503, 2001
12. Kaban LB, Glowacki J: Induced osteogenesis in the repair of experimental mandibular defects in rats. J Dent Res 60:1356, 1981
13. IEC: 61689: Ultrasonics-Physiotherapy Systems-Performance requirements and methods of measurement in the frequency range 0,5 MHz to 5 MHz. Geneva, Switzerland, IEC, 1996
14. IEC: 61161: Ultrasonic Power Measurement in Liquids in the Frequency Range 0,5 MHz to 25 MHz. Geneva, Switzerland, IEC 1992, and Amendment Al, 1998
15. Mayr E, Rudzki MM, Rudzki M, et al: Beschleunigt niedrig intensiver, gepulster Ultraschall die Heilung von Skaphoidfrakturen? Handchir Mikrochir Plast Chir 32:115, 2000
16. Pilla AA, Mont A, Nasser PR, et al: Non-invasive low-intensity pulsed ultrasound accelerates bone healing in the rabbit. J Orthop Trauma 4:246, 1990
17. Yang KH, Parvizi J, Wang SJ, et al: Exposure to low-intensity ultrasound increases aggrecan gene expression in a rat femur fracture model. J Orthop Res 14:802, 1996
18. Wang SJ, Lewallen DG, Bolander ME, et al: Low intensity ultrasound treatment increases strength in a rat femoral fracture model. J Orthop Res 12:40, 1994
19. Reher P, Doan N, Bradnock B, et al: Effect of ultrasound on the production of IL-8, basic FGF and VEGF. Cytokine 11:416, 1999
20. Doan N, Reher P, Meghji S, et al: In vitro effects of therapeutic ultrasound on cell proliferation, protein synthesis, and cytokine production by human fibroblasts, osteoblasts, and monocytes. J Oral Maxillofac Surg 57:409, 1999
21. Fëdotov SN, Minin EA, Borisov IN: Stomatol Mosk 65:4, 1986 [Effect of local cooling and ultrasound on the reparative processes following mandibular fracture]
22. Cavaliere R: Azione coadiuvante degli ultrasuoni nel trattamento delle fratture mascellari. Riv Ital Stomatol 12:1397, 1957
23. Harris M: The conservative management of osteoradionecrosis of the mandible with ultrasound therapy. Br J Oral Maxillofac Surg 30:313, 1992
24. Duarte LR: The stimulation of bone growth by ultrasound. Arch Orthop Trauma Surg 101:153, 1983
25. Parvizi J, Parpura V, Kinnick RR, et al: Low intensity ultrasound increases intracellular concentrations of calcium in chondrocytes. Trans Orthop Res Soc 22:465, 1997
26. Parvizi J, Parpura J, Greenleaf JF, et al: Calcium signaling is required for ultrasound stimulated aggrecan synthesis by rat chondrocytes. J Orthop Res 20:51, 2002
27. Ryaby JT, Bachner EJ, Bendo JA, et al: Low intensity ultrasound increases calcium incorporation in both differentiating cartilage and bone cell cultures. Trans Orthop Res Soc 14:15, 1989
28. Kitchen SS, Partridge CJ: A review of therapeutic ultrasound. Physiotherapy 76:593, 1990
29. Schmitz JP, Hollinger JO: The critical size defect as an experimental model for craniomandibulofacial nonunions. Clin Orthop 205:299, 1986
30. Hollinger JO, Kleinschmidt JC: The critical size defect as an experimental model to test bone repair materials. J Craniofac Surg 1:60, 1990
31. Heiple KG, Chase SW, Herndon CH: A comparative study of the healing process following different types of bone transplantation. Am J Bone Joint Surg 45:1593, 1963
32. Lorente CA, Song BZ, Donoff RB: Healing of bony defects in the irradiated and unirradiated rat mandible. J Oral Maxillofac Surg 50:1305, 1992
33. Schortinghuis J, Ruben JL, Meijer HJA, et al. Microradiography to evaluate bone growth into a rat mandibular defect. Arch Oral Biol 48:155, 2003
34. Brueton RN, Brookes M, Heatley FW: The effect of ultrasound on the repair of a rabbit's tibial osteotomy held in rigid external fixation. Br J Bone Joint Surg 69:494, 1987
35. Lubbers J: The weight of 1.5 MHz ultrasound. Internal report, Department of Biomedical Engineering, University of Groningen, Groningen, The Netherlands, 2001
36. Kaban LB, Glowacki J, Murray JE: Repair of experimental mandibular bony defects in rats. Surg Forum 30:519, 1979
37. Gongloff RK, Whitslow W, Montgomery CK: Use of collagen tubes for implantation of hydroxylapatite. J Oral Maxillofac Surg 43:570, 1985
38. Dahlin C, Linde A, Gottlow J, et al: Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg 81:672, 1988
39. Dahlin C, Sandberg E, Alberius P, et al: Restoration of mandibular nonunion bone defects. An experimental study in rats using an osteopromotive membrane method. Int J Oral Maxillofac Surg 23:237, 1994
40. Linde A, Hedner E: Recombinant bone morphogenetic protein-2 enhances bone healing, guided by osteopromotive e-PTFE membranes: An experimental study in rats. Calcif Tissue Int 56:549, 1995
41. Jones GT, Jian XC, Laskin DM: The effect of L-dopa on the healing of a rat mandibular defect. J Oral Maxillofac Surg 54:470, 1996