High resolution structures of an oxidized and reduced flavoprotein: The water switch in a soluble form of (S)-mandelate dehydrogenase

Journal of Biological Chemistry

Volumn 279, Issue 5, 2004, Pages 3749-3757

  Sukumar, Narayanasami ^a,c   Dewanti, Asteriani R ^b   Mitra, Bharati ^b   Mathews, F Scott ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; ENZYMES; HYDROGEN BONDS; POLYPEPTIDES; PROTONS; SUBSTRATES;

CHIMERIC ENZYMES;

BIOCHEMISTRY;

ALCOHOL DEHYDROGENASE; FLAVOPROTEIN; GLYCINE; GLYOXYLIC ACID DERIVATIVE; HYDROXY ACID OXIDASE A; L MANDELATE DEHYDROGENASE; L-MANDELATE DEHYDROGENASE; MANDELATE DEHYDROGENASE; OXYGEN; PHENYLGLYOXYLIC ACID; TYROSINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CHIMERA; CRYSTAL STRUCTURE; CRYSTALLIZATION; DOSE RESPONSE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYMOLOGY; GENE REARRANGEMENT; HYDROGEN BOND; MEMBRANE BINDING; METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN STRUCTURE; PROTON TRANSPORT; PSEUDOMONAS PUTIDA; SPINACH; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ALCOHOL OXIDOREDUCTASES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVOPROTEINS; GLYCINE; GLYOXYLATES; HYDROGEN BONDING; MANDELIC ACIDS; MODELS, CHEMICAL; MODELS, MOLECULAR; OXYGEN; PROTEIN CONFORMATION; PSEUDOMONAS PUTIDA; SPINACIA OLERACEA; TYROSINE; WATER;

BACTERIA (MICROORGANISMS); PSEUDOMONAS; PSEUDOMONAS PUTIDA; SPINACIA OLERACEA;

EID: 0942265528     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310049200     Document Type: Article

References (33)

1. Tsou, A. Y., Ransom, S. C., Gerlt, J. A., Buechter, D. D., Babbitt, P. C., and Kenyon, G. L. (1990) Biochemistry 29, 9856-9862
2. Mitra, B., Gerlt, J. A., Babbitt, P. C., Koo, C. W., Kenyon, G. L., Joseph, D., and Petsko, G. A. (1993) Biochemistry 32, 12959-12967
3. Diep Le, K. H., and Lederer, F. (1991) J. Biol. Chem. 266, 20877-20881
4. Lederer, F. (1991) in Chemistry and Biochemistry of the Flavoenzymes (Muller, F., ed) Vol. 2, pp. 153-242, CRC Press, Inc., Boca Raton, FL
5. Belmouden, A., Le, K. H., Lederer, F., and Garchon, H. J. (1993) Eur. J. Biochem. 214, 17-25
6. Ghisla, S., and Massey, V. (1991) in Chemistry and Biochemistry of the Flavoenzymes (Muller, F., ed) Vol. 2, pp. 243-289, CRC Press, Inc., Boca Raton, FL
7. Lindqvist, Y., and Branden, C. I. (1989) J. Biol. Chem. 264, 3624-3628
8. Allison, N., O'Donnell, M. J., and Fewson, C. A. (1985) Biochem. J. 231, 407-416
9. Kataoka, M., Shimizu, S., and Yamada, H. (1992) Eur. J. Biochem. 204, 799-806
10. Blobel, G. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 1496-1500
11. Ghisla, S., and Massey, V. (1989) Eur. J. Biochem. 181, 1-17
12. Mattevi, A., Vanoni, M. A., Todone, F., Rizzi, M., Teplyakov, A., Coda, A., Bolognesi, M., and Curti, B. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 7496-7501
13. Lehoux, I. E., and Mitra, B. (1999) Biochemistry 38, 5836-5848
14. Sun, W., Williams, C. H., Jr., and Massey, V. (1996) J. Biol. Chem. 271, 17226-17233
15. Xu, Y., and Mitra, B. (1999) in Flavins and Flavoproteins 1999 (Ghisla, S., Kroneck, P., Macheroux, P., and Sund, H., eds) pp. 487-490, RudolfWeber, Agency for Scientific Publications, Berlin
16. Xu, Y., and Mitra, B. (1999) Biochemistry 38, 12367-12376
17. Sukumar, N., Xu, Y., Gatti, D. L., Mitra, B., and Mathews, F. S. (2001) Biochemistry 40, 9870-9878
18. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
19. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
20. Brünger, A. T. (1992) Nature 355, 472-475
21. Roussel, A., and Cambillau, C. (1989) Turbo Frodo, Silicon Graphics Geometry Partners Directory, pp. 77-78, Silicon Graphic, Mountain View, CA
22. Ramakrishnan, C., and Ramachandran, G. N. (1965) Biophys. J. 5, 909-933
23. Laskowski, R., Thornton, J., Moss, D., and MacArthur, M. (1993) J. Appl. Crystallogr. 26, 283-291
24. Xia, Z.-X., and Mathews, F. S. (1990) J. Mol. Biol. 212, 837-863
25. Lindqvist, Y. (1989) J. Mol. Biol. 209, 151-166
26. Cunane, L. M., Barton, J. D., Chen, Z. W., Welsh, F. E., Chapman, S. K., Reid, G. A., and Mathews, F. S. (2002) Biochemistry 41, 4264-4272
27. Dewanti, A., and Mitra, B. (2003) Biochemistry 42, 12893-12901
28. Xu, Y., Dewanti, A. R., and Mitra, B. (2002) Biochemistry 41, 12313-12319
29. Muller, F. (1991) in Chemistry and Biochemistry of Flavoenzymes (Muller, F., ed) Vol. 1, pp. 1-71, CRC Press, Inc., Boca Raton, FL
30. Lindqvist, Y., Branden, C. I., Mathews, F. S., and Lederer, F. (1991) J. Biol. Chem. 266, 3198-3207
31. Massey, V. (1994) J. Biol. Chem. 269, 22459-22462
32. Sawyer, D. T., and Nanni, E. J. (1981) in Oxygen and Oxy-Radicals in Chemistry and Biology (Sawyer, D. T., and Nanni, E. J., eds) pp. 15-44, Academic Press, New York
33. Wallace, A. C., Laskowski, R. A., and Thornton, J. M. (1995) Protein Eng. 8, 127-134