Effective irreversible alkylating reagents based on the structure of clavulones

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 4, 2004, Pages 837-840

  Tanaka, Hiroshi ^a   Kitade, Makoto ^a,c   Iwashima, Makoto ^b,d   Iguchi, Kazuo ^b   Takahashi, Takashi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^c TAIHO PHARMACEUTICAL CO LTD   (Japan)

^d UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Aldol reactions; Alkylating reagents; Clavulones; Michael reactions; Prostanoids

Indexed keywords

ALKYLATING AGENT; CLAVULONE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG CONJUGATION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICHAEL ADDITION; REACTION ANALYSIS;

EID: 0842346035     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.12.026     Document Type: Article

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