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Volumn 29, Issue 1, 2004, Pages 17-25

Electroneutral Cation-Chloride Cotransporters in the Central Nervous System

Author keywords

GABA; KCC; Neural excitation; Potassium chloride cotransporter

Indexed keywords

4 AMINOBUTYRIC ACID; CHLORIDE ION; COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM ION; UNCLASSIFIED DRUG;

EID: 0842344406     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000010432.44566.21     Document Type: Review
Times cited : (68)

References (67)
  • 1
    • 0032878444 scopus 로고    scopus 로고
    • Molecular biology of distal nephron sodium transport mechanisms
    • Gamba, G. 1999. Molecular biology of distal nephron sodium transport mechanisms. Kidney Int. 56:1606-1622.
    • (1999) Kidney Int. , vol.56 , pp. 1606-1622
    • Gamba, G.1
  • 3
    • 0036193948 scopus 로고    scopus 로고
    • Human and murine phenotypes associated with defects in cation-chloride cotransport
    • Delpire, E. and Mount, D. B. 2002. Human and murine phenotypes associated with defects in cation-chloride cotransport. Annu. Rev. Physiol. 64:803-843.
    • (2002) Annu. Rev. Physiol. , vol.64 , pp. 803-843
    • Delpire, E.1    Mount, D.B.2
  • 6
    • 0028343934 scopus 로고
    • Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter
    • Xu, J.-C., Lytle, C., Zhu, T. T., Payne, J. A., Benz, Jr., E., and Forbush, III, B. 1994. Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter. Proc. Natl. Acad. Sci. USA 91:2201-2205.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2201-2205
    • Xu, J.-C.1    Lytle, C.2    Zhu, T.T.3    Payne, J.A.4    Benz Jr., E.5    Forbush III, B.6
  • 7
    • 0028201013 scopus 로고
    • Molecular cloning, primary structure and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney
    • Gamba, G., Miyanoshita, A., Lombardi, M., Lytton, J., Lee, W. S., Hediger, M. A., and Hebert, S. C. 1994. Molecular cloning, primary structure and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J. Biol. Chem. 269:17713-17722.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17713-17722
    • Gamba, G.1    Miyanoshita, A.2    Lombardi, M.3    Lytton, J.4    Lee, W.S.5    Hediger, M.A.6    Hebert, S.C.7
  • 8
    • 0034644648 scopus 로고    scopus 로고
    • Cloning and functional characterization of a cation Cl-cotransporter interacting protein
    • Caron, L., Rousseau, F., Gagnon, E., and Isenring, P. 2000. Cloning and functional characterization of a cation Cl-cotransporter interacting protein. J Biol. Chem. 275:32027-32036.
    • (2000) J. Biol. Chem. , vol.275 , pp. 32027-32036
    • Caron, L.1    Rousseau, F.2    Gagnon, E.3    Isenring, P.4
  • 9
    • 0842292356 scopus 로고    scopus 로고
    • Cloning and characterization of SLC12A9, a new member of the cation-chloride cotransporter gene family
    • Mount, D. B., Arias I., Xie, Q., Mercado, A., and Gamba, G. 2002. Cloning and characterization of SLC12A9, a new member of the cation-chloride cotransporter gene family. FASEB J 16:A807.
    • (2002) FASEB J. , vol.16
    • Mount, D.B.1    Arias, I.2    Xie, Q.3    Mercado, A.4    Gamba, G.5
  • 10
    • 0035195543 scopus 로고    scopus 로고
    • Alternative splicing and diversity of renal transporters
    • Gamba, G. 2001. Alternative splicing and diversity of renal transporters. Am. J. Physiol. Renal Physiol. 281:F781-F794.
    • (2001) Am. J. Physiol. Renal Physiol. , vol.281
    • Gamba, G.1
  • 13
    • 0035006546 scopus 로고    scopus 로고
    • Alternatively spliced isoform of the apical Na-K-Cl cotransporter gene encodes a furosemide sensitive Na-Cl cotransporter
    • Plata, C., Meade, P., Hall, A. E., Welch, R. C., Vazquez, N., Hebert, S. C., and Gamba, G. 2001. Alternatively spliced isoform of the apical Na-K-Cl cotransporter gene encodes a furosemide sensitive Na-Cl cotransporter. Am. J. Physiol. Renal Physiol. 280:F574-F582.
    • (2001) Am. J. Physiol. Renal Physiol. , vol.280
    • Plata, C.1    Meade, P.2    Hall, A.E.3    Welch, R.C.4    Vazquez, N.5    Hebert, S.C.6    Gamba, G.7
  • 14
    • 0037088671 scopus 로고    scopus 로고
    • Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions
    • Gimenez, I., Isenring, P., and Forbush, III, B. 2002. Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions. J. Biol. Chem. 277:8767-8770.
    • (2002) J. Biol. Chem. , vol.277 , pp. 8767-8770
    • Gimenez, I.1    Isenring, P.2    Forbush III, B.3
  • 16
    • 0035857751 scopus 로고    scopus 로고
    • Localization of the K(+)-Cl(-) cotransporter, KCC3, in the central and peripheral nervous systems: Expression in the choroid plexus, large neurons and white matter tracts
    • Pearson, M. M., Lu, J., Mount, D. B., and Delpire, E. 2001. Localization of the K(+)-Cl(-) cotransporter, KCC3, in the central and peripheral nervous systems: Expression in the choroid plexus, large neurons and white matter tracts. Neuroscience 103:481-491.
    • (2001) Neuroscience , vol.103 , pp. 481-491
    • Pearson, M.M.1    Lu, J.2    Mount, D.B.3    Delpire, E.4
  • 18
    • 0030036478 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat and human: A new member of the cation-chloride cotransporter family
    • Gillen, C. M., Brill, S., Payne, J. A., and Forbush, III, B. 1996. Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat and human: A new member of the cation-chloride cotransporter family. J. Biol. Chem. 271:16237-16244.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16237-16244
    • Gillen, C.M.1    Brill, S.2    Payne, J.A.3    Forbush III, B.4
  • 19
    • 0030059455 scopus 로고    scopus 로고
    • Molecular characterization of a putative K-Cl cotransporter in rat brain: A neuronal-specific isoform
    • Payne, J. A., Stevenson, T. J., and Donaldson, L. F. 1996. Molecular characterization of a putative K-Cl cotransporter in rat brain: A neuronal-specific isoform. J. Biol. Chem. 271:16245-16252.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16245-16252
    • Payne, J.A.1    Stevenson, T.J.2    Donaldson, L.F.3
  • 20
    • 0037663842 scopus 로고    scopus 로고
    • Differential expression pattern of chloride transporters NCC, NKCC2, KCC1, KCC3, KCC4, and AE3 in the developing rat auditory brainstem
    • Becker, M., Nothwang, H. G., and Friauf, E. 2003. Differential expression pattern of chloride transporters NCC, NKCC2, KCC1, KCC3, KCC4, and AE3 in the developing rat auditory brainstem. Cell Tissue Res. 312:155-165.
    • (2003) Cell Tissue Res. , vol.312 , pp. 155-165
    • Becker, M.1    Nothwang, H.G.2    Friauf, E.3
  • 21
    • 0033522877 scopus 로고    scopus 로고
    • Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family
    • Mount, D. B., Mercado, A., Song, L., Xu, J., Geroge, Jr. A., L., Delpire, E., and Gamba, G. 1999. Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family. J. Biol. Chem. 274:16355-16362.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16355-16362
    • Mount, D.B.1    Mercado, A.2    Song, L.3    Xu, J.4    Geroge Jr., A.5    Delpire, E.6    Gamba, G.7
  • 22
    • 0034531318 scopus 로고    scopus 로고
    • K-Cl cotransport: Properties and molecular mechanism
    • Lauf, P. K. and Adragna, N. C. 2000. K-Cl cotransport: Properties and molecular mechanism. Cell Physiol Biochem. 10:341-354.
    • (2000) Cell Physiol Biochem. , vol.10 , pp. 341-354
    • Lauf, P.K.1    Adragna, N.C.2
  • 24
    • 0026585722 scopus 로고
    • Kinetics of D1DS inhibition of swelling-activated K-Cl cotransport in low K shepp erythrocytes
    • Delpire, E. and Lauf, P. K. 1992. Kinetics of D1DS inhibition of swelling-activated K-Cl cotransport in low K shepp erythrocytes. J. Membrane Biol. 126:89-96.
    • (1992) J. Membrane Biol. , vol.126 , pp. 89-96
    • Delpire, E.1    Lauf, P.K.2
  • 26
    • 0028587564 scopus 로고
    • Role of protein phosphorylation in control of K flux pathways of trout red blood cells
    • Cossins, A. R, Weaver, Y. R., Lykkeboe, G., and Nielsen, O. B. 1994. Role of protein phosphorylation in control of K flux pathways of trout red blood cells. Am. J. Physiol Cell Physiol. 267:C1641-C1650
    • (1994) Am. J. Physiol Cell Physiol. , vol.267
    • Cossins, A.R.1    Weaver, Y.R.2    Lykkeboe, G.3    Nielsen, O.B.4
  • 27
    • 0035799988 scopus 로고    scopus 로고
    • The differential expression patterns of messenger RNAs encoding K-Cl cotransporters (KCC1, 2) and Na-K-2Cl cotransporter (NKCC1) in the rat nervous system
    • Kanaka, C., Ohno, K., Okabe, A., Kuriyama, K., Itoh, T., Fukuda, A., and Sato, K. 2001. The differential expression patterns of messenger RNAs encoding K-Cl cotransporters (KCC1, 2) and Na-K-2Cl cotransporter (NKCC1) in the rat nervous system. Neuroscience 104:933-946.
    • (2001) Neuroscience , vol.104 , pp. 933-946
    • Kanaka, C.1    Ohno, K.2    Okabe, A.3    Kuriyama, K.4    Itoh, T.5    Fukuda, A.6    Sato, K.7
  • 29
    • 0035124822 scopus 로고    scopus 로고
    • Neuronal restrictive silencing element is found in the KCC2 gene: Molecular basis for KCC2-specific expression in neurons
    • Karadsheh, M. F. and Delpire. E. 2001. Neuronal restrictive silencing element is found in the KCC2 gene: Molecular basis for KCC2-specific expression in neurons. J Neurophysiol. 85:995-997.
    • (2001) J. Neurophysiol. , vol.85 , pp. 995-997
    • Karadsheh, M.F.1    Delpire, E.2
  • 31
    • 0033564808 scopus 로고    scopus 로고
    • Developmental regulation of the neuronal-specific isoform of K-Cl cotransporter KCC2 in postnatal rat brains
    • Lu, J., Karadsheh, M., and Delpire, E. 1999. Developmental regulation of the neuronal-specific isoform of K-Cl cotransporter KCC2 in postnatal rat brains. J Neurobiol. 39:558-568.
    • (1999) J. Neurobiol. , vol.39 , pp. 558-568
    • Lu, J.1    Karadsheh, M.2    Delpire, E.3
  • 34
    • 0030614820 scopus 로고    scopus 로고
    • 2+ oscillations mediated by the synergistic excitatory actions of GABA(A) and NMDA receptors in the neonatal hippocampus
    • 2+ oscillations mediated by the synergistic excitatory actions of GABA(A) and NMDA receptors in the neonatal hippocampus. Neuron 18:243-255.
    • (1997) Neuron , vol.18 , pp. 243-255
    • Leinekugel, X.1    Medina, I.2    Khalilov, I.3    Ben Ari, Y.4    Khazipov, R.5
  • 35
    • 0033166227 scopus 로고    scopus 로고
    • Long-term potentiation of GABAergic synaptic transmission in neonatal rat hippocampus
    • Caillard, O., Ben Ari, Y., and Gaiarsa, J. L. 1999. Long-term potentiation of GABAergic synaptic transmission in neonatal rat hippocampus. J. Physiol. 518:109-119.
    • (1999) J. Physiol. , vol.518 , pp. 109-119
    • Caillard, O.1    Ben Ari, Y.2    Gaiarsa, J.L.3
  • 36
    • 0035907025 scopus 로고    scopus 로고
    • GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition
    • Ganguly, K., Schinder, A. F., Wong, S. T., and Poo, M. 2001. GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition. Cell 105:521-532.
    • (2001) Cell , vol.105 , pp. 521-532
    • Ganguly, K.1    Schinder, A.F.2    Wong, S.T.3    Poo, M.4
  • 37
    • 0032537056 scopus 로고    scopus 로고
    • Glycine-receptor activation is required for receptor clustering in spinal neurons
    • Kirsch, J. and Betz, H. 1998. Glycine-receptor activation is required for receptor clustering in spinal neurons. Nature 392:717-720.
    • (1998) Nature , vol.392 , pp. 717-720
    • Kirsch, J.1    Betz, H.2
  • 38
    • 0042178356 scopus 로고    scopus 로고
    • GABA depolarizes neuronal progenitors of the postnatal subventricular zone via GABAA receptor activation
    • Wang, D. D., Krueger, D. D., and Bordey, A. 2003. GABA depolarizes neuronal progenitors of the postnatal subventricular zone via GABAA receptor activation. J. Physiol. 550:785-800.
    • (2003) J. Physiol. , vol.550 , pp. 785-800
    • Wang, D.D.1    Krueger, D.D.2    Bordey, A.3
  • 39
    • 0036719162 scopus 로고    scopus 로고
    • Excitatory actions of gaba during development: The nature of the nurture
    • Ben Ari, Y. 2002. Excitatory actions of gaba during development: The nature of the nurture. Nat. Rev. Neurosci. 3:728-739.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 728-739
    • Ben Ari, Y.1
  • 40
    • 0036717789 scopus 로고    scopus 로고
    • Is there more to GABA than synaptic inhibition?
    • Owens, D. F. and Kriegstein, A. R. 2002. Is there more to GABA than synaptic inhibition? Nat. Rev. Neurosci. 3:715-727.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 715-727
    • Owens, D.F.1    Kriegstein, A.R.2
  • 43
    • 0034329336 scopus 로고    scopus 로고
    • Potassium-coupled chloride cotransport controls intracellular chloride in rat neocortical pyramidal neurons
    • DeFazio, R. A., Keros, S., Quick, M. W., and Hablitz, J. J. 2000. Potassium-coupled chloride cotransport controls intracellular chloride in rat neocortical pyramidal neurons. J. Neurosci. 20:8069-8076.
    • (2000) J. Neurosci. , vol.20 , pp. 8069-8076
    • DeFazio, R.A.1    Keros, S.2    Quick, M.W.3    Hablitz, J.J.4
  • 44
    • 0033564407 scopus 로고    scopus 로고
    • - accumulation and depletion in cultured rat midbrain neurons
    • - accumulation and depletion in cultured rat midbrain neurons. J. Neurosci. 19:4695-4704.
    • (1999) J. Neurosci. , vol.19 , pp. 4695-4704
    • Jarolimek, W.1    Lewen, A.2    Misgeld, U.3
  • 45
    • 0033930643 scopus 로고    scopus 로고
    • Reversibility and cation selectivity of the K(+)-Cl(-) cotransport in rat central neurons
    • Kakazu, Y., Uchida, S., Nakagawa, T., Akaike, N., and Nabekura, J. 2000. Reversibility and cation selectivity of the K(+)-Cl(-) cotransport in rat central neurons. J. Neurophysiol. 84:281-288.
    • (2000) J. Neurophysiol. , vol.84 , pp. 281-288
    • Kakazu, Y.1    Uchida, S.2    Nakagawa, T.3    Akaike, N.4    Nabekura, J.5
  • 47
    • 0034990498 scopus 로고    scopus 로고
    • Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition
    • Hubner, C. A., Stein, V., Hermans-Borgmeyer, I., Meyer, T., Ballanyi, K., and Jentsch, T. J. 2001. Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition. Neuron 30:515-524.
    • (2001) Neuron , vol.30 , pp. 515-524
    • Hubner, C.A.1    Stein, V.2    Hermans-Borgmeyer, I.3    Meyer, T.4    Ballanyi, K.5    Jentsch, T.J.6
  • 48
  • 55
    • 0035013319 scopus 로고    scopus 로고
    • Mutation analysis of the potassium chloride cotransporter KCC3 (SLC12A6) in rolandic and idiopathic generalized epilepsy
    • Steinlein, O. K., Neubauer, B. A., Sander, T., Song, L., Stoodt, J., and Mount, D. B. 2001. Mutation analysis of the potassium chloride cotransporter KCC3 (SLC12A6) in rolandic and idiopathic generalized epilepsy. Epilepsy Res. 44:191-195.
    • (2001) Epilepsy Res. , vol.44 , pp. 191-195
    • Steinlein, O.K.1    Neubauer, B.A.2    Sander, T.3    Song, L.4    Stoodt, J.5    Mount, D.B.6
  • 56
    • 0037171857 scopus 로고    scopus 로고
    • Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter KCC4
    • Boettger, T., Hubner, C. A., Maier, H., Rust, M. B., Beck, F. X., and Jentsch, T. J. 2002. Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter KCC4. Nature 416: 874-878.
    • (2002) Nature , vol.416 , pp. 874-878
    • Boettger, T.1    Hubner, C.A.2    Maier, H.3    Rust, M.B.4    Beck, F.X.5    Jentsch, T.J.6
  • 57
    • 0036924837 scopus 로고    scopus 로고
    • Patterns of cation-chloride cotransporter expression during embryonic rodent CNS development
    • Li, H., Tornberg, J., Kaila, K., Airaksinen, M. S., and Rivera, C. 2002. Patterns of cation-chloride cotransporter expression during embryonic rodent CNS development. Eur. J. Neurosci. 16:2358-2370.
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 2358-2370
    • Li, H.1    Tornberg, J.2    Kaila, K.3    Airaksinen, M.S.4    Rivera, C.5
  • 58
    • 0029151610 scopus 로고
    • Molecular characterization of the epithelial Na-K-Cl cotransporter isoforms
    • Payne, J. A., and Forbush, III, B. 1995. Molecular characterization of the epithelial Na-K-Cl cotransporter isoforms. Curr. Opin. Cell Biol. 7:493-503.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 493-503
    • Payne, J.A.1    Forbush III, B.2
  • 60
    • 0029074919 scopus 로고
    • Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon
    • Payne, J. A., Xu, J.-C., Haas, M., Lytle, C. Y., Ward, D., and Forbush, III, B. 1995. Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon. J. Biol. Chem. 270: 17977-17985.
    • (1995) J. Biol. Chem. , vol.270 , pp. 17977-17985
    • Payne, J.A.1    Xu, J.-C.2    Haas, M.3    Lytle, C.Y.4    Ward, D.5    Forbush III, B.6
  • 61
    • 0030723081 scopus 로고    scopus 로고
    • Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: A possible mechanism underlying GABA's excitatory role in immature brain
    • Plotkin, M. D., Snyder, E. Y., Hebert, S. C., and Delpire, E. 1997. Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: A possible mechanism underlying GABA's excitatory role in immature brain. J. Neurobiol. 33: 781-795.
    • (1997) J. Neurobiol. , vol.33 , pp. 781-795
    • Plotkin, M.D.1    Snyder, E.Y.2    Hebert, S.C.3    Delpire, E.4
  • 62
    • 0034666837 scopus 로고    scopus 로고
    • Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice
    • Sung, K. W., Kirby, M., McDonald, M. P., Lovinger, D. M., and Delpire, E. 2000. Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice. J Neurosci. 20:7531-7538.
    • (2000) J. Neurosci. , vol.20 , pp. 7531-7538
    • Sung, K.W.1    Kirby, M.2    McDonald, M.P.3    Lovinger, D.M.4    Delpire, E.5
  • 64
    • 0033037730 scopus 로고    scopus 로고
    • Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter
    • Delpire, E., Lu, J., England, R., Dull, C., and Thorne, T. 1999. Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter. Nat. Genet. 22:192-195.
    • (1999) Nat. Genet. , vol.22 , pp. 192-195
    • Delpire, E.1    Lu, J.2    England, R.3    Dull, C.4    Thorne, T.5
  • 66
    • 0034003979 scopus 로고    scopus 로고
    • Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter
    • Pace, A. J., Lee, E., Athirakul, K., Coffman, T. M., O'Brien, D. A., and Koller, B. H. 2000. Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter. J. Clin. Invest. 105:441-450.
    • (2000) J. Clin. Invest. , vol.105 , pp. 441-450
    • Pace, A.J.1    Lee, E.2    Athirakul, K.3    Coffman, T.M.4    O'Brien, D.A.5    Koller, B.H.6
  • 67
    • 0034554915 scopus 로고    scopus 로고
    • Cation-chloride cotransporters in neuronal communication
    • Delpire, E. 2000. Cation-chloride cotransporters in neuronal communication. News Physiol. Sci. 15:309-312.
    • (2000) News Physiol. Sci. , vol.15 , pp. 309-312
    • Delpire, E.1


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