Beta-adrenergic receptor blockade and the angiotensin-converting enzyme deletion polymorphism in patients with chronic heart failure

European Journal of Heart Failure

Volumn 6, Issue 1, 2004, Pages 17-21

  De Groote, Pascal ^a   Helbecque, Nicole ^b   Lamblin, Nicolas ^a,b   Hermant, Xavier ^b   Amouyel, Philippe ^b   Bauters, Christophe ^a,b   Dallongeville, Jean ^b  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

Author keywords

Angiotensin converting enzyme; Beta blockers; Congestive heart failure; Polymorphism

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE; RADIOISOTOPE;

ADULT; AGED; ANGIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE COURSE; DNA DETERMINATION; DNA EXTRACTION; DOSE RESPONSE; DRUG EFFECT; DRUG RESPONSE; DRUG TOLERANCE; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENETIC POLYMORPHISM; HEART EJECTION FRACTION; HEART FAILURE; HEART FUNCTION; HUMAN; INTERMETHOD COMPARISON; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; PATIENT SELECTION; PRIORITY JOURNAL; RECEPTOR BLOCKING; SURVIVAL RATE; TITRIMETRY;

ADRENERGIC BETA-ANTAGONISTS; AGED; FEMALE; FOLLOW-UP STUDIES; GENE DELETION; GENOTYPE; HEART FAILURE, CONGESTIVE; HUMANS; MALE; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT;

EID: 0842326412     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejheart.2003.09.006     Document Type: Article

References (18)

1. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet. 353:1999;9-13.
2. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet. 353:1999;2001-2007.
3. Packer M., Coats A.J., Fowler M.B., et al. Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med. 344:2001;1651-1658.
4. Cody R.J., Franklin K.W., Kluger J., Laragh J.H. Sympathetic responsiveness and plasma norepinephrine during therapy of chronic congestive heart failure with captopril. Am J Med. 72:1982;791-797.
5. Gilbert E.M., Sandoval A., Larrabee P., Renlund D.G., O'Connell J.B., Bristow M.R. Lisinopril lowers cardiac adrenergic drive and increases beta-receptor density in the failing human heart. Circulation. 88:1993;472-480.
6. McNamara D.M., Holubkov R., Janosko K., et al. Pharmacogenetic interactions between beta-blocker therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure. Circulation. 103:2001;1644-1648.
7. Hall S.A., Cigarroa C.G., Marcoux L., Risser R.C., Grayburn P.A., Eichhorn E.J. Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade. J Am Coll Cardiol. 25:1995;1154-1161.
8. Olsen S.L., Gilbert E.M., Renlund D.G., Taylor D.O., Yanowitz F.D., Bristow M.R. Carvedilol improves left ventricular function and symptoms in chronic heart failure: a double-blind randomized study. J Am Coll Cardiol. 25:1995;1225-1231.
9. Bristow M.R., Gilbert E.M., Abraham W.T., et al. Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. MOCHA Investigators. Circulation. 94:1996;2807-2816.
10. Lechat P., Escolano S., Golmard J.L., et al. Prognostic value of bisoprolol-induced hemodynamic effects in heart failure during the Cardiac Insufficiency BIsoprolol Study (CIBIS). Circulation. 96:1997;2197-2205.
11. de Groote P., Millaire A., Foucher-Hossein C., et al. Right ventricular ejection fraction is an independent predictor of survival in patients with moderate heart failure. J Am Coll Cardiol. 32:1998;948-954.
12. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16:1988;1215.
13. Hamon M., Bauters C., Amant C., et al. Relation between the deletion polymorphism of the angiotensin-converting enzyme gene and late luminal narrowing after coronary angioplasty. Circulation. 92:1995;296-299.
14. Lowes B.D., Gilbert E.M., Abraham W.T., et al. Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. N Engl J Med. 346:2002;1357-1365.
15. Kukin M.L., Kalman J., Charney R.H., et al. Prospective, randomized comparison of effect of long-term treatment with metoprolol or carvedilol on symptoms, exercise, ejection fraction, and oxidative stress in heart failure. Circulation. 99:1999;2645-2651.
16. Lechat P., Hulot J.S., Escolano S., et al. Heart rate and cardiac rhythm relationships with bisoprolol benefit in chronic heart failure in CIBIS II Trial. Circulation. 103:2001;1428-1433.
17. Cambien F., Alhenc-Gelas F., Herbeth B., et al. Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy Study. Am J Hum Genet. 43:1988;774-780.
18. Rigat B., Hubert C., Alhenc-Gelas F., Cambien F., Corvol P., Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 86:1990;1343-1346.