메뉴 건너뛰기




Volumn 44, Issue 6, 2003, Pages 374-384

Increased Serum Titers of Autoantibodies Against Oxidized LDL Cholesterol in Young Healthy Adults: An Evidence of a Protective Effect of These Antibodies?

Author keywords

Atherosclerosis; Autoantibodies; Oxidative stress; Oxidized LDL

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN B; AUTOANTIBODY; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 0842312309     PISSN: 10117970     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (36)
  • 2
    • 0023285779 scopus 로고
    • Free radical effects on membrane protein in myocardial inschemia/reperfusion injury
    • Kako KJ: Free radical effects on membrane protein in myocardial inschemia/reperfusion injury. J Mol Cell Cardiol 1987; 19: 209-211.
    • (1987) J Mol Cell Cardiol , vol.19 , pp. 209-211
    • Kako, K.J.1
  • 3
    • 0032513135 scopus 로고    scopus 로고
    • Peroxidative damage to cardiac mitochondria: Cytochrome oxidase and cardiolipin alterations
    • Paradies G, Ruggiere FM, Petrosillo G, et al: Peroxidative damage to cardiac mitochondria: cytochrome oxidase and cardiolipin alterations. FEBS Lett 1998; 424: 155-158.
    • (1998) FEBS Lett , vol.424 , pp. 155-158
    • Paradies, G.1    Ruggiere, F.M.2    Petrosillo, G.3
  • 4
    • 0027352741 scopus 로고
    • Anti-oxidized low-density lipoprotein antibodies in patients with coronary heart disease and normal healthy volunteers
    • Virella G, Virella I, Leman RB, et al: Anti-oxidized low-density lipoprotein antibodies in patients with coronary heart disease and normal healthy volunteers. Int J Clin Lab Res 1993; 23: 95-101.
    • (1993) Int J Clin Lab Res , vol.23 , pp. 95-101
    • Virella, G.1    Virella, I.2    Leman, R.B.3
  • 5
    • 0026586813 scopus 로고
    • Autoantibody against oxidized LDL and progression of carotid atherosclerosis
    • Salonen JT. Yla-Herttuala S, Yamamoto R, et al: Autoantibody against oxidized LDL and progression of carotid atherosclerosis. Lancet 1992; 339: 883.
    • (1992) Lancet , vol.339 , pp. 883
    • Salonen, J.T.1    Yla-Herttuala, S.2    Yamamoto, R.3
  • 6
    • 0027761813 scopus 로고
    • Specificity of autoantibodies against axidized LDL as an additional marker for atherosclerotic risk
    • Maggi E, Finardi G, Poli M, et al: Specificity of autoantibodies against axidized LDL as an additional marker for atherosclerotic risk. Coronary Artery Disease 1993; 4: 1119-1125.
    • (1993) Coronary Artery Disease , vol.4 , pp. 1119-1125
    • Maggi, E.1    Finardi, G.2    Poli, M.3
  • 7
    • 0028923681 scopus 로고
    • Patients with early-onset peripheral vascular disease have increased levels of autoantibodies against oxidized LDL
    • Bergmark C, Wu R, De Faire U, et al: Patients with early-onset peripheral vascular disease have increased levels of autoantibodies against oxidized LDL. Arterioscler Thromb Vasc Biol 1995; 15: 441-445.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 441-445
    • Bergmark, C.1    Wu, R.2    De Faire, U.3
  • 8
    • 0035151814 scopus 로고    scopus 로고
    • Antibodies to oxidized LDL in relation to intima-media thickness in carotid and femoral arteries in 58-year-old subjectively clinically healthy men
    • Hulthe J, Bokemark L, Fagerberg B, et al: Antibodies to oxidized LDL in relation to intima-media thickness in carotid and femoral arteries in 58-year-old subjectively clinically healthy men. Arterioscler Thromb Vasc Biol 2001; 21: 101.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 101
    • Hulthe, J.1    Bokemark, L.2    Fagerberg, B.3
  • 9
    • 0030912927 scopus 로고    scopus 로고
    • Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis
    • Iribarren C, Folsom AR, Jacobs DR, et al: Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. Arterioscler Thromb Vasc Biol 1997; 17: 1171.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1171
    • Iribarren, C.1    Folsom, A.R.2    Jacobs, D.R.3
  • 10
    • 0034061545 scopus 로고    scopus 로고
    • Antibodies against oxidized LDL and carotid artery intima-media thickness in a healthy population
    • Fukumoto M, Shoji T, Emoto M, et al: Antibodies against oxidized LDL and carotid artery intima-media thickness in a healthy population. Arterioscler Thromb Vasc Biol 2000; 20: 703-710.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 703-710
    • Fukumoto, M.1    Shoji, T.2    Emoto, M.3
  • 11
    • 0035142672 scopus 로고    scopus 로고
    • Antibodies to oxidized LDL in relation to carotid atherosclerosis, cell adhesion molecules and phospholipase A2
    • Hulthe J, Wiklund O, Hurt-Camejio Eva, et al: Antibodies to oxidized LDL in relation to carotid atherosclerosis, cell adhesion molecules and phospholipase A2. Arterioscler Thromb Vasc Biol 2001; 21: 269.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 269
    • Hulthe, J.1    Wiklund, O.2    Hurt-Camejio, E.3
  • 12
    • 0027971549 scopus 로고
    • Antibody against oxidized low-density lipoprotein predicting myocardial infarction
    • Puurunen M, Manttari M, Manninen V, et al: Antibody against oxidized low-density lipoprotein predicting myocardial infarction. Arch Intern Med 1994; 154: 2603-2605.
    • (1994) Arch Intern Med , vol.154 , pp. 2603-2605
    • Puurunen, M.1    Manttari, M.2    Manninen, V.3
  • 13
    • 0034700233 scopus 로고    scopus 로고
    • Circulating immune complexes in 50-year-old men as a strong and independent risk factor for myocardial infarction
    • Musfafa A, Nituyanand S, Berglund L, et al: Circulating immune complexes in 50-year-old men as a strong and independent risk factor for myocardial infarction. Circulation 2000; 102: 2576-2581.
    • (2000) Circulation , vol.102 , pp. 2576-2581
    • Musfafa, A.1    Nituyanand, S.2    Berglund, L.3
  • 14
    • 0031459413 scopus 로고    scopus 로고
    • Antibodies against cardiolipin and oxidatively modified LDL in 50-year-old men predict myocardial infarction
    • Wu R, Nityanand S, Berglund L, et al: Antibodies against cardiolipin and oxidatively modified LDL in 50-year-old men predict myocardial infarction. Arterioscler Thromb Vasc Biol 1997; 17 (11): 3159-3163.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , Issue.11 , pp. 3159-3163
    • Wu, R.1    Nityanand, S.2    Berglund, L.3
  • 15
    • 0032709478 scopus 로고    scopus 로고
    • Autoantibodies against oxidatively modified LDL do not constitute a risk factor for stroke
    • Ejaz A, Trifunovic J, Stegmayr B, et al: Autoantibodies against oxidatively modified LDL do not constitute a risk factor for stroke. Stroke 1999; 2541-2546.
    • (1999) Stroke , pp. 2541-2546
    • Ejaz, A.1    Trifunovic, J.2    Stegmayr, B.3
  • 16
    • 0030053467 scopus 로고    scopus 로고
    • Sensitive detection of oxidatively modified low density lipoprotein using a monoclonal antibody
    • Itabe H, Yamamoto H, Imanaka T, et al: Sensitive detection of oxidatively modified low density lipoprotein using a monoclonal antibody. J Lipid Res 1996; 37: 45-53.
    • (1996) J Lipid Res , vol.37 , pp. 45-53
    • Itabe, H.1    Yamamoto, H.2    Imanaka, T.3
  • 17
    • 0033990553 scopus 로고    scopus 로고
    • Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels inhealthy subjects
    • Shoji T, Nishzawa Y, Fukumoto M, et al: Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels inhealthy subjects. Atherosclerosis 2000; 148: 171-177.
    • (2000) Atherosclerosis , vol.148 , pp. 171-177
    • Shoji, T.1    Nishzawa, Y.2    Fukumoto, M.3
  • 18
    • 0023237194 scopus 로고
    • Turnover and tissue sites of degradation of glucosylated low density lipoprotein in normal and immunized rabbits
    • Wiklund O, Witztum JL, Carew TE, et al: Turnover and tissue sites of degradation of glucosylated low density lipoprotein in normal and immunized rabbits. J Lipid Res 1987; 28: 1098-1109.
    • (1987) J Lipid Res , vol.28 , pp. 1098-1109
    • Wiklund, O.1    Witztum, J.L.2    Carew, T.E.3
  • 19
    • 0037896283 scopus 로고    scopus 로고
    • Monoclonal autoantibodies specific for oxidized low-density lipoproteins
    • Horkko S, Bird DA, Miller E, et al: Monoclonal autoantibodies specific for oxidized low-density lipoproteins. J Clin Invest 1999; 103: 117-128.
    • (1999) J Clin Invest , vol.103 , pp. 117-128
    • Horkko, S.1    Bird, D.A.2    Miller, E.3
  • 20
    • 0023718536 scopus 로고
    • Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes: A possible mechanism of foam cell formation
    • Griffith RL, Virella, GT, Stevenson HC, et al: Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes: a possible mechanism of foam cell formation. J Exp Med 1988; 168: 1041-1059.
    • (1988) J Exp Med , vol.168 , pp. 1041-1059
    • Griffith, R.L.1    Virella, G.T.2    Stevenson, H.C.3
  • 21
    • 0026472712 scopus 로고
    • Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates
    • Khoo JC, Miller E, Pio F, et al: Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates. Arterioscler Thromb Vasc Biol 1992; 12: 1258-1266.
    • (1992) Arterioscler Thromb Vasc Biol , vol.12 , pp. 1258-1266
    • Khoo, J.C.1    Miller, E.2    Pio, F.3
  • 22
    • 0030814770 scopus 로고    scopus 로고
    • Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type I/II gene
    • Ling WH, Lougheed M, Suzuki H, et al: Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type I/II gene. J Clin Invest 1997; 100: 244-252.
    • (1997) J Clin Invest , vol.100 , pp. 244-252
    • Ling, W.H.1    Lougheed, M.2    Suzuki, H.3
  • 23
    • 0025719392 scopus 로고
    • T lymphocytes inhibit the vascular response to injury
    • Hansson GK, Holm J, Holm S, et al: T lymphocytes inhibit the vascular response to injury. Proc Natl Acad Sci USA. 1991; 94: 2516-2520.
    • (1991) Proc Natl Acad Sci USA , vol.94 , pp. 2516-2520
    • Hansson, G.K.1    Holm, J.2    Holm, S.3
  • 24
    • 0029092584 scopus 로고
    • Enhanced development of atherosclerosis in cholesterol-fed rabbids by suppression of cell-mediated immunity
    • Rosellar SE, Schonfeld G, Daugherty A: Enhanced development of atherosclerosis in cholesterol-fed rabbids by suppression of cell-mediated immunity. J Clin Invest 1995; 96: 1389-1394.
    • (1995) J Clin Invest , vol.96 , pp. 1389-1394
    • Rosellar, S.E.1    Schonfeld, G.2    Daugherty, A.3
  • 25
    • 0031001972 scopus 로고    scopus 로고
    • T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse
    • Dansky HM, Charlton SA, Harper MM, et al: T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci 1997; 94: 4642-4646.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 4642-4646
    • Dansky, H.M.1    Charlton, S.A.2    Harper, M.M.3
  • 26
    • 0031817689 scopus 로고    scopus 로고
    • Antibody titers against oxidized LDL are not elevated in patients with familiar hypercholesterolemia
    • Hulthe J, Wikstrand J, Lidell A, et al: Antibody titers against oxidized LDL are not elevated in patients with familiar hypercholesterolemia. Arterioscler Thromb Vasc Biol 1998; 18: 1203-1211.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1203-1211
    • Hulthe, J.1    Wikstrand, J.2    Lidell, A.3
  • 27
    • 0029819268 scopus 로고    scopus 로고
    • Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus
    • Uusitupa M, Niskanen L, Luoma J, et al: Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1996; 16: 1236.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1236
    • Uusitupa, M.1    Niskanen, L.2    Luoma, J.3
  • 28
    • 0028881323 scopus 로고
    • Autoantibodies against oxidized low density lipoproteins (oxLDL): Characterization of antibody isotype, subclass, affinity and effect on the macrophage uptake of oxLDL
    • Wu R, Lefvert AK: Autoantibodies against oxidized low density lipoproteins (oxLDL): characterization of antibody isotype, subclass, affinity and effect on the macrophage uptake of oxLDL. Clin Exp Immunol 1995; 102: 174-180.
    • (1995) Clin Exp Immunol , vol.102 , pp. 174-180
    • Wu, R.1    Lefvert, A.K.2
  • 29
    • 0026082959 scopus 로고
    • Biology of disease: Involvement of the immune system in human atherogenesis: Current knowledge and unanswered questions
    • Libby P, Hansson GK: Biology of disease: involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Invest 1991; 64: 5-15.
    • (1991) Lab Invest , vol.64 , pp. 5-15
    • Libby, P.1    Hansson, G.K.2
  • 30
    • 0842311171 scopus 로고    scopus 로고
    • The revolution of HDL
    • Zannis V, Kardasis D: The revolution of HDL. Atheroma 2002; 6: 1-2.
    • (2002) Atheroma , vol.6 , pp. 1-2
    • Zannis, V.1    Kardasis, D.2
  • 31
    • 8944258922 scopus 로고    scopus 로고
    • The yin and yang of oxidation in the development of the fatty streak
    • Navab M, Berliner J, Watson A, et al: The yin and yang of oxidation in the development of the fatty streak. Arterioscler Thromb Vasc Biol 1996; 16: 831-838.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 831-838
    • Navab, M.1    Berliner, J.2    Watson, A.3
  • 32
    • 0035818556 scopus 로고    scopus 로고
    • Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: An idea whose time for testing is coming, part I
    • Shah P, Kaul S, Nilsson J, et al: Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: an idea whose time for testing is coming, part I. Circulation 2001; 104: 2376-2383.
    • (2001) Circulation , vol.104 , pp. 2376-2383
    • Shah, P.1    Kaul, S.2    Nilsson, J.3
  • 33
    • 0035856555 scopus 로고    scopus 로고
    • Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: An idea whose time for testing is coming, part II
    • Shah P, Kaul S, Nilsson J, et al: Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: an idea whose time for testing is coming, part II. Circulation 2001; 104: 2498-2502.
    • (2001) Circulation , vol.104 , pp. 2498-2502
    • Shah, P.1    Kaul, S.2    Nilsson, J.3
  • 34
    • 0035856544 scopus 로고    scopus 로고
    • High-density lipoprotein and the dynamics of atherosclerotic lesions
    • Navab M, Van Lenten B, Reddy S, et al: High-density lipoprotein and the dynamics of atherosclerotic lesions. Circulation 2001; 104: 2386-2387.
    • (2001) Circulation , vol.104 , pp. 2386-2387
    • Navab, M.1    Van Lenten, B.2    Reddy, S.3
  • 35
    • 0035170772 scopus 로고    scopus 로고
    • Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice
    • Tsimikas S, Palinski W, Witztum J, et al: Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 2001; 21: 95-101.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 95-101
    • Tsimikas, S.1    Palinski, W.2    Witztum, J.3
  • 36
    • 0029885602 scopus 로고    scopus 로고
    • Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls
    • Van de Vijver L, Steyger R, Van Poppel G, et al: Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls. Atherosclerosis 1996; 122: 245-253.
    • (1996) Atherosclerosis , vol.122 , pp. 245-253
    • Van De Vijver, L.1    Steyger, R.2    Van Poppel, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.