Enhanced Protein Profiling Arrays with ELISA-Based Amplification for High-Throughput Molecular Changes of Tumor Patients' Plasma

Clinical Cancer Research

Volumn 10, Issue 2, 2004, Pages 598-609

  Huang, Ruochun ^a   Lin, Ying ^a   Shi, Qian ^a   Flowers, Lisa ^a   Ramachandran, Sumathi ^a   Horowitz, Ira R ^a   Parthasarathy, Sampath ^a   Huang, Ruo Pan ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; ANGIOGENIN; ANTIBODY; BIOTIN; EPIDERMAL GROWTH FACTOR; INTERLEUKIN 8; PLATELET DERIVED GROWTH FACTOR; VASCULOTROPIN;

ADULT; AGED; ANTIBODY LABELING; ARTICLE; BIOMEDICINE; BLOOD SAMPLING; CANCER PATIENT; CLUSTER ANALYSIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FEMALE GENITAL TRACT TUMOR; FLUORESCENCE; GENE AMPLIFICATION; HIGH THROUGHPUT SCREENING; HUMAN; MAJOR CLINICAL STUDY; PLASMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; PROTEIN MICROARRAY; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOTIN; CELL LINE, TUMOR; CHEMILUMINESCENT MEASUREMENTS; CLUSTER ANALYSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIDERMAL GROWTH FACTOR; FEMALE; GENITAL NEOPLASMS, FEMALE; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-8; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MULTIGENE FAMILY; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLATELET-DERIVED GROWTH FACTOR; PROTEIN ARRAY ANALYSIS; RIBONUCLEASE, PANCREATIC; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 0842311612     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-0697-03     Document Type: Article

References (59)

1. Ferrara, N., and Davis-Smyth, T. The biology of vascular endothelial growth factor. Endocr. Rev., 18: 4-25, 1997.
2. Strieter, R. M., Polverini, P. J., Arenberg, D. A., Walz, A., Opdenakker, G., Van Damme, J., and Kunkel, S. L. Role of C-X-C chemokines as regulators of angiogenesis in lung cancer. J. Leukoc. Biol., 57: 752-762, 1995.
3. Huang, S., Mills, L., Mian, B., Tellez, C., McCarty, M., Yang, X. D., Gudas, J. M., and Bar-Eli, M. Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. Am. J. Pathol., 161: 125-134, 2002.
4. Vallee, B. L., and Riordan, J. F. Organogenesis and angiogenin. Cell Mol. Life Sci., 53: 803-815, 1997.
5. Dunn, I. F., and Heese, O., and Black, P. M. Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs. J. Neurooncol., 50: 121-137, 2000.
6. Kim, H. R., Yu, J., and Ustach, C. Platelet-derived growth factor signaling and human cancer. J. Biochem. Mol. Biol., 36: 49-59, 2003.
7. Auguste, P., Gursel, D. B., Lemiere, S., Reimers, D., Cuevas, P., Carceller, F., Di Santo, J. P., and Bikfalvi, A. Inhibition of fibroblast growth factor/fibroblast growth factor receptor activity in glioma cells impedes tumor growth by both angiogenesis-dependent and -independent mechanisms. Cancer Res., 61: 1717-1726, 2001.
8. Song, M., Ramaswamy, S., Ramachandran, S., Flowers, L. C., Horowitz, I. R., Rock, J. A., and Parthasarathy, S. Angiogenic role for glycodelin in tumorigenesis. Proc. Natl. Acad. Sci. USA, 98: 9265-9270, 2001.
9. Li, J., Post, M., Volk, R., Gao, Y., Li, M., Metais, C., Sato, K., Tsai, J., Aird, W., Rosenberg, R. D., Hampton, T. G., Sellke, F., Carmeliet, P., and Simons, M. PR39, a peptide regulator of angiogenesis. Nat. Med., 6: 49-55, 2000.
10. O'Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. R., and Folkman, J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell, 88: 277-285, 1997.
11. Claesson-Welsh, L., Welsh, M., Ito, N., Anand-Apte, B., Soker, S., Zetter, B., O'Reilly, M., and Folkman, J. Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD. Proc. Natl. Acad. Sci. USA, 95: 5579-5583, 1998.
12. Dixelius, J., Larsson, H., Sasaki, T., Holmqvist, K., Lu, L., Engstrom, A., Timpl, R., Welsh, M., and Claesson-Welsh, L. Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis. Blood, 95: 3403-3411, 2000.
13. Vailhe, B., and Feige, J. J. Thrombospondins as anti-angiogenic therapeutic agents. Curr. Pharm. Des, 9: 583-588, 2003.
14. Yue, T. L., Wang, X., Louden, C. S., Gupta, S., Pillarisetti, K., Gu, J. L., Hart, T. K., Lysko, P. G., and Feuerstein, G. Z. 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: possible role for stress-activated protein kinase signaling pathway and Fas expression. Mol. Pharmacol., 51: 951-962, 1997.
15. Folkman, J. Tumor angiogenesis and tissue factor. Nat. Med., 2: 167-168, 1996.
16. Kutryk, M. J., and Stewart, D. J. Angiogenesis of the heart. Microsc. Res. Tech., 60: 138-158, 2003.
17. Martin, A., Komada, M. R., and Sane, D. C. Abnormal angiogenesis in diabetes mellitus. Med. Res. Rev., 23: 117-145, 2003.
18. Taylor, R. N., Lebovic, D. I., and Mueller, M. D. Angiogenic factors in endometriosis. Ann. N. Y. Acad. Sci., 955: 89-100, 2002.
19. Folkman, J. Angiogenesis-dependent diseases. Semin. Oncol., 28: 536-542, 2001.
20. Folkman, J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med., 1: 27-31, 1995.
21. Folkman, J. Role of angiogenesis in tumor growth and metastasis. Semin. Oncol., 29: 15-18, 2002.
22. Folkman, J. Angiogenesis and angiogenesis inhibition: an overview. EXS (Basel), 79: 1-8, 1997.
23. Kumar, S., Ghellal, A., Li, C., Byme, G., Haboubi, N., Wang, J. M., and Bundred, N. Breast carcinoma: vascular density determined using CD105 antibody correlates with tumor prognosis. Cancer Res., 59: 856-861, 1999.
24. Li, C., Wilson, P. B., Levine, E., Barber, J., Stewart, A. L., and Kumar, S. TGF-β1 levels in pre-treatment plasma identify breast cancer patients at risk of developing post-radiotherapy fibrosis. Int. J. Cancer, 84: 155-159, 1999.
25. Ghellal, A., Li, C., Hayes, M., Byrne, G., Bundred, N., and Kumar, S. Prognostic significance of TGF β1 and TGF β3 in human breast carcinoma. Anticancer Res., 20: 4413-4418, 2000.
26. Choi, H. J., Hyun, M. S., Jung, G. J., Kim, S. S., and Hong, S. H. Tumor angiogenesis as a prognostic predictor in colorectal carcinoma with special reference to mode of metastasis and recurrence. Oncology, 55: 575-581, 1998.
27. Homer, J. J., Greenman, J., and Stafford, N. D. Circulating angiogenic cytokines as tumour markers and prognostic factors in head and neck squamous cell carcinoma. Clin. Otolaryngol., 27: 32-37, 2002.
28. Blann, A. D., Li, J. L., Li, C., and Kumar, S. Increased serum VEGF in 13 children with Wilms' tumour falls after surgery but rising levels predict poor prognosis. Cancer Lett., 173: 183-186, 2001.
29. Skoldenberg, E. G., Christiansson, J., Sandstedt, B., Larsson, A., Lackgren, G., and Christofferson, R. Angiogenesis and angiogenic growth factors in Wilms tumor. J. Urol., 165: 2274-2279, 2001.
30. Chopra, V., Dinh, T. V., and Hannigan, E. V. Serum levels of interleukins, growth factors and angiogenin in patients with endometrial cancer. J. Cancer Res. Clin. Oncol., 123: 167-172, 1997.
31. Arici, A. Local cytokines in endometrial tissue: the role of interleukin-8 in the pathogenesis of endometriosis. Ann. N. Y. Acad. Sci., 955: 101-109, 2002.
32. Fasciani, A., D'Ambrogio, G., Bocci, G., Luisi, S., Artini, P. G., and Genazzani, A. R. Vascular endothelial growth factor and interleukin-8 in ovarian cystic pathology. Fertil. Steril., 75: 1218-1221, 2001.
33. Huang, R. P. Detection of multiple proteins in an antibody-based protein microarray system. J. Immunol. Methods, 255: 1-13, 2001.
34. Huang, R. P., Huang, R., Fan, Y., and Lin, Y. Simultaneous detection of multiple cytokines from conditioned media and patient's sera by an antibody-based protein array system. Anal. Biochem., 294: 55-62, 2001.
35. Huang, R., Lin, Y., Wang, C. C., Gano, J., Lin, B., Shi, Q., Boynton, A., Burke, J., and Huang, R. P. Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology. Cancer Res., 62: 2806-2812, 2002.
36. Lin, Y., Huang, R., Santanam, N., Liu, Y., Parthasarathy, S., and Huang, R. Profiling of human cytokines in healthy individuals with vitamin E supplementation by antibody array. Cancer Lett., 187: 17-24, 2002.
37. Horowitz, I. R., Cho, C., Song, M., Flowers, L. C., Santanam, N., Parthasarathy, S., and Ramachandran, S. Increased glycodelin levels in gynecological malignancies. Int. J. Gynecol. Cancer, 11: 173-179, 2001.
38. Schweitzer, B., Wiltshire, S., Lambert, J., O'Malley, S., Kukanskis, K., Zhu, Z., Kingsmore, S. F., Lizardi, P. M., and Ward, D. C. Inaugural article: immunoassays with rolling circle DNA amplification: a versatile platform for ultrasensitive antigen detection. Proc. Natl. Acad. Sci. USA, 97: 10113-10119, 2000.
39. Zhang, D. Y., Brandwein, M., Hsuih, T. C., and Li, H. Amplification of target-specific, ligation-dependent circular probe. Gene (Amst.), 211: 277-285, 1998.
40. Thomas, D. C., Nardone, G. A., and Randall, S. K. Amplification of padlock probes for DNA diagnostics by cascade rolling circle amplification or the polymerase chain reaction. Arch. Pathol. Lab Med., 123: 1170-1176, 1999.
41. Fire, A., and Xu, S. Q. Rolling replication of short DNA circles., 92: 4641-4645, 1995.
42. Glenjen, N., Mosevoll, K. A., and Bruserud, O. Serum levels of angiogenin, basic fibroblast growth factor and endostatin in patients receiving intensive chemotherapy for acute myelogenous leukemia. Int. J. Cancer, 101: 86-94, 2002.
43. Ochs, M. F., and Godwin, A. K. Microarrays in cancer: research and applications. Biotechniques, Suppl: 4-15, 2003.
44. RingnerM, Peterson C Microarray-based cancer diagnosis with artificial neural networks. Biotechniques, March (Suppl.): 30-35, 2003.
45. Buchhaults, P., Zhang, Z., Chen, Y., Wang, T., St Croix, B., Saha, S., Bardelli, A., Morin, P., Polyak, K., Hruban, R., Velculescu, V. E., and Shih, I. Idendtifying tumor origin using a gene expression-based classification map. Cancer Res., 63: 4144-4149, 2003.
46. Petricoin III, E. F., Ardekani, A. M., Hitt, B. A., Levine, P. J., Fusaro, V. A., Steinberg, S. M., Mills, G. B., Simone, C., Fishman, D., Kohn, E. C., and Liotta, L. A. Use of proteomic pattems in serum to identify ovarian cancer. Lancet, 359: 572-577, 2002.
47. Ivarsson, K., Runesson, E., Sundfeldt, K., Haeger, M., Hedin, L., Janson, P. O., and Brannstrom, M. The chemotactic cytokine interleukin-8-a cyst fluid marker for malignant epithelial ovarian cancer? Gynecol. Oncol., 71: 420-423, 1998.
48. Ivarsson, K., Ekerydh, A., Fyhr, I. M., Janson, P. O., and Brannstrom, M. Upregulation of interleukin-8 and polarized epithelial expression of interleukin-8 receptor A in ovarian carcinomas. Acta Obstet. Gynecol. Scand., 79: 777-784, 2000.
49. Chopra, V., Dinh, T. V., and Hannigan, E. V. Circulating serum levels of cytokines and angiogenic factors in patients with cervical cancer. Cancer Investig, 16: 152-159, 1998.
50. Akoum, A., Lawson, C., McColl, S., and Villeneuve, M. Ectopic endometrial cells express high concentrations of interleukin (IL)-8 in vivo regardless of the menstrual cycle phase and respond to oestradiol by up-regulating IL-1-induced IL-8 expression in vitro. Mol. Hum. Reprod., 7: 859-866, 2001.
51. Barton, D. P., Cai, A., Wendt, K., Young, M., Gamero, A., and De Cesare, S. Angiogenic protein expression in advanced epithelial ovarian cancer. Clin. Cancer Res., 3: 1579-1586, 1997.
52. Henriksen, R., Funa, K., Wilander, E., Backstrom, T., Ridderheim, M., and Oberg, K. Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms. Cancer Res., 53: 4550-4554, 1993.
53. Di Lieto, A., De Rosa, G., De Falco, M., Iannotti, F., Staibano, S., Pollio, F., Scaramellino, M., and Salvatore, G. Relationship between platelet-derived growth factor expression in leiomyomas and uterine volume changes after gonadotropin-releasing hormone agonist treatment. Hum. Pathol., 33: 220-224, 2002.
54. Harrison-Woolrych, M. L., Chamock-Jones, D. S., and Smith, S. K. Quantification of messenger ribonucleic acid for epidermal growth factor in human myometrium and leiomyomata using reverse transcriptase polymerase chain reaction. J. Clin. Endocrinol. Metab, 78: 1179-1184, 1994.
55. Shaarawy, M., and El Sharkawy, S. A. Biomarkers of intrinsic angiogenic and anti-angiogenic activity in patients with endometrial hyperplasia and endometrial cancer. Acta Oncol., 40: 513-518, 2001.
56. Doldi, N., Bassan, M., Gulisano, M., Broccoli, V., Boncinelli, E., and Ferrari, A. Vascular endothelial growth factor messenger ribonucleic acid expression in human ovarian and endometrial cancer. Gynecol. Endocrinol., 10: 375-382, 1996.
57. Wei, L. H., Kuo, M. L., Chen, C. A., Cheng, W. F., Cheng, S. P., Hsieh, F. J., and Hsieh, C. Y. Interleukin-6 in cervical cancer: the relationship with vascular endothelial growth factor. Gynecol. Oncol., 82: 49-56, 2001.
58. Gentry, C. C., Okolo, S. O., Fong, L. F., Crow, J. C., Maclean, A. B., and Perrett, C. W. Quantification of vascular endothelial growth factor-A in leiomyomas and adjacent myometrium. Clin. Sci. (Lond), 101: 691-695, 2001.
59. Harrison-Woolrych, M. L., Sharkey, A. M., Chamock-Jones, D. S., and Smith, S. K. Localization and quantification of vascular endothelial growth factor messenger ribonucleic acid in human myometrium and leiomyomata. J. Clin. Endocrinol. Metab, 80: 1853-1858, 1995.