Soluble LDL-R are formed by cell surface cleavage in response to phorbol esters

European Journal of Biochemistry

Volumn 271, Issue 3, 2004, Pages 524-533

  Begg, Michael J ^a,d   Sturrock, Edward D ^a   Van Der Westhuyzen, Deneys R ^b,c  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^c LEXINGTON VA MEDICAL CENTER   (United States)

^d Biopolymer Unit   (South Africa)

Author keywords

Ectodomain shedding; Internalization signal; LDL R; Low density lipoprotein

Indexed keywords

3,4 DICHLOROISOCOUMARIN; 4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; ANTIBODY; APROTININ; CELL SURFACE PROTEIN; EDETIC ACID; EGTAZIC ACID; HYDROXAMIC ACID DERIVATIVE; IODINE 125; LEUPEPTIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE PROTEIN; METALLOPROTEINASE INHIBITOR; METHIONINE; MUTANT PROTEIN; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PEPSTATIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHORAMIDON; PROTEINASE INHIBITOR; SULFUR 35; TOSYLLYSYL CHLOROMETHYL KETONE; TUMOR NECROSIS FACTOR ALPHA PROTEASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY LABELING; ARTICLE; BINDING ASSAY; CELL LABELING; CELL STRAIN HEPG2; CELL SURFACE; CHO CELL; CONTROLLED STUDY; ENDOCYTOSIS; GENE DELETION; GENETIC TRANSFECTION; HOMOZYGOTE; HUMAN; HUMAN CELL; INTERNALIZATION; ISOTOPE LABELING; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN SECRETION; SKIN FIBROBLAST; SOLUBILITY; WILD TYPE;

AMINO ACID SEQUENCE; CELL LINE; CELL MEMBRANE; DNA, COMPLEMENTARY; ENDOCYTOSIS; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RECEPTORS, LDL; SOLUBILITY; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0842308984     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03953.x     Document Type: Article

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