Biodefense-driven murine model of pneumonic melioidosis

Infection and Immunity

Volumn 71, Issue 1, 2003, Pages 584-587

  Jeddeloh, J A ^a,b   Fritz, D L ^a   Waag, D M ^a   Hartings, J M ^a   Andrews, G P ^a  

^a US Army Medical Research   (United States)

^b Center for Emerging Technologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VACCINE;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BURKHOLDERIA PSEUDOMALLEI; DEATH; GENE DELETION; GENE MUTATION; MELIOIDOSIS; MOUSE; MUTANT; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL;

ANIMALS; BIOTERRORISM; BURKHOLDERIA PSEUDOMALLEI; DISEASE MODELS, ANIMAL; HUMANS; MELIOIDOSIS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PNEUMONIA, BACTERIAL; RIBOSOMAL PROTEINS; VIRULENCE;

EID: 0037220633     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.1.584-587.2003     Document Type: Article

References (18)

1. Alibek, K., and S. Handelman. 1999. Biohazard: The chilling true story of the largest covert biological weapons program in the world, 1st ed. Random House, New York, N.Y.
2. Barnes, J. L., G. C. Ulett, N. Ketheesan, T. Clair, P. M. Summers, and R. G. Hirst. 2001. Induction of multiple chemokine and colony-stimulating factor genes in experimental Burkholderia pseudomallei infection. Immunol. Cell Biol. 79:490-501.
3. Bjorkman, J., P. Samuelsson, D. I. Andersson, and D. Hughes. 1999. Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium. Mol. Microbiol. 31:53-58.
4. Bray, M. P., M. J. Martinez, D. Kefauver, M. West, and C. Roy. 2002. Treatment of aerosolized cowpox virus infection in mice with aerosolized cidofovir. Antivir. Res. 54:129-142.
5. Dance, D. A. B. 1999. Melioidosis, p. 430-437. In R. L. Geurrant, D. H. Walker, and P. F. Weller (ed.), Tropical infectious diseases: Principles, pathogens and practice, 1st ed., vol. 1. Churchill Livingstone, Philadelphia, Pa.
6. DeShazer, D., P. J. Brett, R. Carlyon, and D. E. Woods. 1997. Mutagenesis of Burkholderia pseudomallei with Tn5-OT182: Isolation of motility mutants and molecular characterization of the flagellin structural gene. J. Bacteriol. 179:2116-2125.
7. Fritz, D. L., P. A. Vogel, D. R. Brown, and D. M. Waag. 1999. The hamster model of intraperitoneal Burkholderia mallei. Vet. Pathol. 36:276-291.
8. Guyton, A. C. 1947. Measurement of the respiratory minute volume of laboratory animals. Am. J. Physiol. 150:70-77.
9. Heine, H. S., M. J. England, D. M. Waag, and W. R. Byrne. 2001. In vitro antibiotic susceptibilities of Burkholderia mallei (causative agent of glanders) determined by broth microdilution and E-test. Antimicrob. Agents Chemother. 45:2119-2121.
10. Hoppe, I., B. Brenneke, M. Rohde, A. Kreft, S. Häiußler, A. Reganzerowski, and I. Steinmetz. 1999. Characterization of a murine model of melioidosis: Comparison of different strains of mice. Infect. Immun. 67:2891-2900.
11. Liu, B., G. C. Koo, E. H. Yap, K. L. Chua, and Y.-H. Gan. 2002. Model of differential susceptibility to mucosal Burkholderia pseudomallei infection. Infect. Immun. 70:504-511.
12. Moore, R. A., D. DeShazer, S. Reckseidler, A. Weissman, and D. E. Woods. 1999. Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei. Antimicrob. Agents Chemother. 43:465-470.
13. Nigg, C., J. Ruch, E. Scott, and K. Noble. 1956. Enhancement of virulence of Malleomyces pseudomallei. J. Bacteriol. 71:530-541.
14. Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
15. Santanirand, P., V. S. Harley, D. A. B. Dance, B. S. Drasar, and G. J. Bancroft. 1999. Obligatory role of gamma interferon for host survival in a murine model of infection with Burkholderia pseudomallei. Infect. Immun. 67:3593-3600.
16. Waag, D. M., M. J. England, and M. L. Pitt. 1997. Comparative efficacy of a Coxiella burnetii chloroform methanol residue (CMR) vaccine and a licensed cellular vaccine (Q-Vax) in rodents challenged by aerosol. Vaccine 15:1779-1783.
17. Woods, D. E., D. DeShazer, R. A. Moore, P. J. Brett, M. N. Burtnick, S. L. Reckseidler, and M. D. Senkiw. 1999. Current studies on the pathogenesis of melioidosis. Microbes Infect. 1:157-162.
18. Yabuuchi, E., Y. Kosako, H. Oyaizu, I. Yano, T. Ezaki, and M. Arakawa. 1992. Proposal of Burkholderia gen nov. and transfer of seven species of the genus Pseudomonas homology group II to the new genus, with the type species Burkholderia cepacia (Palleroni and Holmes 1981) comb. nov. Microbiol. Immunol. 36:1251-1275.