Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus

Journal of Asian Natural Products Research

Volumn 6, Issue 2, 2004, Pages 93-97

  Ning, Li Li ^a,b   Han, Jian ^a   Zhang, Xing Yi ^c   Guo, Hong Zhu ^a   Bi, Kai Shun ^b   Guo, De An ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c CENTER FOR DRUG EVALUATION   (China)

Author keywords

Biotransformation; Catharanthus roseus; Cell suspension cultures; Triptolide; Triptonide

Indexed keywords

12BETA,13ALPHA DIHYDROXYTRIPTONIDE; TERPENOID DERIVATIVE; TRIPTOLIDE; TRIPTONIDE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOIMMUNE DISEASE; BIOTRANSFORMATION; CATHARANTHUS ROSEUS; CELL SUSPENSION; DRUG STRUCTURE; HERBAL MEDICINE; NONHUMAN; REACTION ANALYSIS;

BIOTRANSFORMATION; CATHARANTHUS; CELLS, CULTURED; DITERPENES; PHENANTHRENES; TRITERPENES;

CATHARANTHUS ROSEUS;

EID: 0842268522     PISSN: 10286020     EISSN: None     Source Type: Journal    
DOI: 10.1080/1028602031000135567     Document Type: Article

References (18)

1. Wang, X.W. and Xie, H. (1999), Drugs Future 24, 991-997.
2. Kupchan, S.M., Court, W.A., Dailey, R.G., Gilmore, C.J. and Bryan, R.F. (1972), J. Am. Chem. Soc. 94, 7194-7195.
3. Yang, Y.L., Liu, Z.H., Tolosa, E., Yang, J.W. and Li, L.S. (1998), Immunopharmacology 40, 139-149.
4. Chan, E.W.C., Cheng, S.C.S., Sin, F.W.Y. and Xie, Y. (2001), Toxicol. Lett. 122, 81-87.
5. Tengchaisri, T., Chawengkirttikul, R., Rachaphaew, N., Reutrakul, V., Sangsuwan, R. and Sirisinha, S. (1998), Cancer Lett. 133, 169-175.
6. Deng, J.R., Gu, K.X., Gao, J.W., Xu, L.F., Yu, Y.H. and Tang, M.Y. (1991), Acta Acad. Med. Sin. 13, 398-402.
7. Deng, J.R., Feng, K.L., Gu, K.X., Xu, L.F., Tang, M.Y., Yu, Y.H. and Gao, J.W. (1994), Acta Acad. Med. Sin. 16, 24-27.
8. Yu, D.Q., Zhang, D.M., Wang, H.B. and Liang, X.T. (1992), Acta Pharm. Sin. 27, 830-836.
9. Yang, D., Ye, X.Y. and Xu, M. (2000), J. Org. Chem. 65, 2208-2217.
10. Ma, P.C., Lu, X.Y. and Wan, L.L. (1992), J. China Pharm. Univ. 23, 135-139.
11. Zhan, J.X., Guo, H.Z., Dai, J.G., Zhang, Y.X. and Guo, D.A. (2002), Tetrahedron Lett. 43, 4519-4521.
12. Dai, J.G., Gong, Z., Zhu, D.M., Guo, H.Z., Zheng, J.H. and Guo, D.A. (2002), Acta Bot. Sin. 44, 377-378.
13. Dai, J.G., Ye, M., Guo, H.Z., Zhu, W.H., Zhang, D.Y., Hu, Q., Zheng, J.H. and Guo, D.A. (2002), Tetrahedron 58, 5659-5668.
14. Ye, M., Dai, J.G., Guo, H.Z. and Guo, D.A. (2002), Tetrahedron Lett. 43, 8535-8538.
15. Zhan, J.X., Guo, H.Z., Han, J., Ning, L.L., Zhang, Y.X. and Guo, D.A. (2002), J. Nat. Prod. 65, 1693-1695.
16. Dai, J.G., Cui, Y.J., Zhu, W.H., Guo, H.Z., Ye, M., Hu, Q., Zhang, D.Y., Zheng, J.H. and Guo, D.A. (2002), Planta Med. 68, 1113-1117.
17. Ye, M., Han, J., Guo, H.Z. and Guo, D.A. (2002), Magn. Reson. Chem. 40, 786-788.
18. Ma, P.C., Lu, X.Y., He, C.H. and Zheng, Q.T. (1991), Acta Bot. Sin. 33, 370-377.