Growth Hormone Treatment for Idiopathic Short Stature: Implications for Practice and Policy

Archives of Pediatrics and Adolescent Medicine

Volumn 158, Issue 2, 2004, Pages 108-110

  Cuttler, Leona ^a   Silvers, J B ^b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; RECOMBINANT GROWTH HORMONE;

ADOLESCENT; BODY HEIGHT; CHILD; CLINICAL TRIAL; DRUG EFFECT; DRUG EFFICACY; DRUG INDICATION; EDITORIAL; FOOD AND DRUG ADMINISTRATION; HEALTH CARE ACCESS; HEALTH CARE AVAILABILITY; HEALTH CARE COST; HEALTH CARE POLICY; HORMONAL THERAPY; HUMAN; IDIOPATHIC DISEASE; MEDICAL PRACTICE; NORMAL HUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; SHORT STATURE; UNITED STATES;

ADOLESCENT; BODY HEIGHT; CHILD; CHILD, PRESCHOOL; GROWTH HORMONE; HEALTH POLICY; HUMANS; UNITED STATES;

EID: 0842268408     PISSN: 10724710     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpedi.158.2.108     Document Type: Editorial

References (28)

1. FDA talk paper: FBA approves Humatrope for short stature [US Food and Drug Administration Web site]. Available at: http://www.fda.gov/bbs/topics/ANSWERS/2003/ANS01242.html. Accessed August 26, 2003.
2. Postrel V. Going to great lengths. New York Times. August 31, 2003;sect 6:16.
3. Que V, Prakash S. Human growth hormone: FDA approves drug for use in healthy, short children [National Public Radio Web site]. August 14, 2003. Available at: http://discover.npr.org/features/feature.jhtml?wfld=1392897. Accessed August 14, 2003.
4. FDA drug approvals list. [US Food and Drug Administration Web site.] August 12, 2002. Available at: http://www.fda.gov/cder/da/da.htm. Accessed September 2, 2003.
5. Cuttler L. Growth disorders in children. In: Nieder M, Super D, Kliegman R, eds. Practical Strategies of Pediatric Diagnosis and Therapy. Philadelphia, Pa: WB Saunders Co; 1995.
6. Finkelstein BS, Silvers JB, Marrero U, Neuhauser D, Cuttler L. Insurance coverage, physician recommendations, and access to emerging treatments: growth hormone therapy for childhood short stature. JAMA. 1998;279:663-668.
7. Rosenfeld R, Cuttler L. Growth and maturation. In: De Groot L, Jameson L, eds. Endocrinology. 4th ed. Philadelphia, Pa: WB Saunders Co; 2000.
8. Allen DB, Brook CG, Bridges NA, Hindmarsh PC, Guyda HJ, Frazier D. Therapeutic controversies: growth hormone (GH) treatment of non-GH deficient subjects. J Clin Endocrinol Metab. 1994;79:1239-1248.
9. Lantos J, Siegler M, Cuttler L. Ethical issues in growth hormone therapy. JAMA. 1989;261:1020-1024.
10. Saenger P. The case in support of Gh therapy. J Pediatr. 2000;136:106-109; discussion 109-110.
11. Voss LD. Growth hormone therapy for the short normal child: who needs it and who wants it? the case against growth hormone therapy. J Pediatr. 2000;136:103-106.
12. Grumbach MM. Growth hormone therapy and the short end of the stick. N Engl J Med. 1988;319:238-241.
13. Considerations related to the use of recombinant human growth hormone in children: American Academy of Pediatrics Committee on Drugs and Committee on Bioethics. Pediatrics. 1997;99:122-129.
14. AACE. AACE clinical practice guidelines for growth hormone use in adults and children. Endocrine Practice. 1998;4:165-173.
15. Oberfield SE. Growth hormone use in normal, short children - a plea for reason. N Engl J Med. 1999;340:557-559.
16. Endocrinologic and Metabolic Drugs Advisory Committee. Humatrope for Non-Growth Hormone Deficient Short Stature. Indianapolis, Ind: Lilly Research Laboratories; 2003. Briefing Document.
17. Finkelstein B, Imperiale T, Speroff T, Marrero U, Radcliffe D, Cuttler L. The effect of growth hormone therapy on height in children with idiopathic short stature: a meta analysis. Arch Pediatr Adolesc Med. 2002;156:230-240.
18. Orloff DG. Approval letter: HumatropPen injection device and draft package insert. [Food and Drug Administration Center for Drug Evaluation Research Web site]. July 25, 2003. Available at: http://www.fda.gov/cder/foi/appletter/2003 /19640se1-033ltr.pdf. Accessed September 3, 2003.
19. Recombinant human growth hormone. Med Lett Drugs Ther. 1994;36:77-78.
20. Growth-hormone-releasing factor for growth hormone deficiency. Med Lett Drugs Ther. 1999;41:2-3.
21. The Annie E. Casey Foundation, Population Reference Bureau. US Population: The Basics. Washington, DC: US Bureau of the Census; 2002.
22. Downie AB, Mulligan J, McCaughey ES, Stratford RJ, Betts PR, Voss LD. Psychological response to growth hormone treatment in short normal children. Arch Dis Child. 1996;75:32-35.
23. Zimet GD, Cutler M, Litvene M, Dahms W, Owens R, Cuttler L. Psychological adjustment of children evaluated for short stature: a preliminary report. J Dev Behav Pediatr. 1995;16:264-270.
24. Zimet GD, Owens R, Dahms W, Cutler M, Litvene M, Cuttler L. Psychosocial outcome of children evaluated for short stature. Arch Pediatr Adolesc Med. 1997;151:1017-1023.
25. Sandberg DE, Voss LD. The psychosocial consequences of short stature: a review of the evidence. Best Pract Res Clin Endocrinol Metab. 2002;16:449-463.
26. Boulton TJ, Smith R, Single T. Psychosocial growth failure: a positive response to growth hormone and placebo. Acta Paediatr. 1992;81:322-325.
27. Persico N, Postlewaite A, Silverman D. The Effect of Adolescent Experience on Labor Market Outcomes: The Case of Height. Philadelphia: University of Pennsylvania; 2002.
28. Graham J. Growing pains: should hormone injections be used to help short kids fit in? Chicago Tribune Magazine. October 21, 2001;10:14-20.