Isolation and characterization of Candida albicans homologue of RAP1, a repressor and activator protein gene in Saccharomyces cerevisiae

Yeast

Volumn 21, Issue 1, 2004, Pages 1-10

  Uemura, Hiroshi ^a   Watanabe Yoshida, Miyuki ^b   Ishii, Nobuya ^b   Shinzato, Tomoko ^a   Haw, Robin ^a,c  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Candida albicans; RAP1; Saccharomyces cerevisiae; Silencing; Telomere; Transcription

Indexed keywords

FUNGAL PROTEIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; RAP1 PROTEIN; REPRESSOR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CANDIDA ALBICANS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; DNA HYBRIDIZATION; DNA SEQUENCE; FUNGAL GENETICS; FUNGUS ISOLATION; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE FUNCTION; GENE IDENTIFICATION; GENE ISOLATION; GENETIC CONSERVATION; HOMEOBOX; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; ORGANISM COLONY; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; REPRESSOR GENE; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BASE SEQUENCE; CANDIDA ALBICANS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ESCHERICHIA COLI; FUNGAL PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE ELONGATION FACTORS; PROTEIN HYBRIDIZATION; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, FUNGAL; SEQUENCE ALIGNMENT; TELOMERE-BINDING PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

CANDIDA; CANDIDA ALBICANS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0742324820     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/yea.1048     Document Type: Article

References (39)

1. Callebaut I, Mornon J-P. 1997. From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. FEBS Lett 400: 25-30.
2. Delgado ML, Gil ML, Gozalbo D. 2003. Candida albicans TDH3 gene promotes secretion of internal invertase when expressed in Saccharomyces cerevisiae as a glyceraldehyde-3-phosphate dehydrogenase-invertase fusion protein. Yeast 20: 713-722.
3. Devlin C, Tice-Baldwin K, Shore D, Arndt KT. 1991. RAP1 is required for BAS1/BAS2- and GCR4-dependent transcription of the yeast HIS4 gene. Mol Cell Biol 11: 3642-3651.
4. Gehring WJ, Qian YQ, Billeter M, et al. 1994. Homeodomain-DNA recognition. Cell 78: 211-223.
5. Gillum AM, Tsay EYH, Kirsch DR. 1984. Isolation of the Candida albicans gene for orotidine 5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol Gen Genet 198: 179-182.
6. Gilson E, Roberge M, Giraldo R, Rhodes D, Gasser S. 1993. Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. J Mol Biol 231: 293-310.
7. Goncalves PM, Maurer K, Amerongen GVN, et al. 1996. C-terminal domains of general regulatory factors Abf1p and Rap1p in Saccharomyces cerevisiae display functional similarity. Mol Microbiol 19: 535-543.
8. Graham IR, Haw RA, Spink KG, Holden KA, Chambers A. 1999. In vivo analysis of functional regions within yeast Rap1p. Mol Cell Biol 19: 7481-7490.
9. Hardy CFJ, Balderes D, Shore D. 1992a. Dissection of a carboxy-terminal region of the yeast regulatory protein RAP1 with effects on both transcriptional activation and silencing. Mol Cell Biol 12: 1209-1217.
10. Hardy CFJ, Sussel L, Shore D. 1992b. A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation. Genes Dev 6: 801-814.
11. Haw R, Yarragudi AD, Uemura H. 2001. Isolation of a Candida glabrata homologue of RAP1, a regulator of transcription and telomere function in Saccharomyces cerevisiae. Yeast 18: 1277-1284.
12. Henry YAL, Chambers A, Tsang JSH, Kingsman AJ, Kingsman SM. 1990. Characterization of the DNA binding domain of the yeast RAP1 protein. Nucleic Acids Res 18: 2617-2623.
13. Ishii N, Yamamoto M, Lahm HW, et al. 1997a. A DNA-binding protein from Candida albicans that binds to the RPG box of Saccharomyces cerevisiae and the telomeric repeat sequence of C. albicans. Microbiology 143: 417-427.
14. Ishii N, Yamamoto M, Yoshihara F, Arisawa M, Aoki Y. 1997b. Biochemical and genetic characterization of Rbf1p, a putative transcription factor of Candida albicans. Microbiology 143: 429-435.
15. Ito H, Fukuda Y, Murata K, Kimura A. 1983. Transformation of intact yeast cells treated with alkali cations. J Bacteriol 153: 163-168.
16. Konig P, Giraldo R, Chapman L, Rhodes D. 1996. The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA. Cell 85: 125-136.
17. Kurtz S, Shore D. 1991. RAP1 protein activates and silences transcription of mating type genes in yeast. Genes Dev 5: 616-628.
18. Larson GP, Castanotto D, Rossi JJ, Malafa MP. 1994. Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue. Gene 150: 35-41.
19. Li B, Oestreich S, de Lange T. 2000. Identification of human Rap1: implications for telomere evolution. Cell 101: 471-483.
20. Maneu V, Cervera AM, Gozalbo MD. 1996. Molecular cloning and characterization of a Candida albicans gene (EFB1) coding for the elongation factor EF-1β. FEMS Microbiol Lett 145: 157-162.
21. Moretti P, Freeman K, Coodly L, Shore D. 1994. Evidence that a complex of SIR proteins interacts with the silencer and telomere binding protein RAP1. Genes Dev 8: 2257-2269.
22. Muller T, Gilson E, Schmidt R, et al. 1994. Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. J Struct Biol 113: 1-12.
23. Nakayama H, Mio T, Nagahashi S, et al. 2000. Tetracycline-regulated system to tightly control gene expression in the pathogenic fungus Candida albicans. Infest. Immun 68: 6712-6719.
24. Ogata K, Morikawa S, Nakamura H, et al. 1994. Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices. Cell 79: 639-648.
25. Pla J, Perez-Diaz RM, Navarro-Garcia F, Sanchez M, Nombela C. 1995. Cloning of the Candida albicans HIS1 gene by direct complementation of a C. albicans histidine auxotroph using an improved double-ARS shuttle vector. Gene 165: 115-120.
26. Sandini S, Melchionna R, Bromuro C, La VR. 2002. Gene expression of 70 kDa heat shock protein of Candida albicans: transcriptional activation and response to heat shock. Med Mycol 40: 471-478.
27. Santos MA, Tuite MF. 1995. The CUG codon is decoded in vivo as serine and not leucine in Candida albicans. Nucleic Acids Res 23: 1481-1486.
28. Schmitt ME, Brown TA, Trumpower BL. 1990. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res 18: 3091-3092.
29. Sherman F, Fink GR, Hicks JB (eds). 1986. Methods in Yeast Genetics. Cold Spring Harbor Laboratory Press: New York.
30. Shore D. 1994. RAP1: a protean regulator in yeast. Trends Genet 10: 408-412.
31. Sikorski RS, Hieter P. 1989. A system of shuttle vectors and yeast host strains designated for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
32. Sussel L, Shore D. 1991. Separation of transcriptional activation and silencing function of the RAP1-encoded repressor/activator protein 1: isolation of viable mutant affecting both silencing and telomere length. Proc Natl Acad Sci USA 88: 7749-7753.
33. Tornow J, Zeng X, Gao W, Santangelo GM. 1993. GCR1 a transcriptional activator in Saccharomyces cerevisiae, complexes with RAP1 and can function without its DNA binding domain. EMBO J 12: 2431-2437.
34. Uemura H, Wickner RB. 1988. Suppression of chromosomal mutations affecting M1 virus replication in Saccharomyces cerevisiae by a variant of a viral RNA segment (L-A) that encodes coat protein. Mol Cell Biol 8: 938-944.
35. Vernet T, Dignard D, Thomas DY. 1987. A family of yeast expression vectors containing the phage fl intergenic region. Gene 52: 225-233.
36. Vignais MJ, Sentenac A. 1989. Asymmetric DNA bending induced by the yeast multifunctional factor TUF. J Biol Chem 264: 8463-8466.
37. Wotton D, Shore D. 1997. A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. Genes Dev 11: 748-760.
38. Yamada-Okabe T, Shimmi O, Doi R, et al. 1996. Isolation of the mRNA-capping enzyme and ferric-reductase-related genes from Candida albicans. Microbiology 142: 2515-2523.
39. Yang X, Talibi D, Weber S, Poisson G, Raymond M. 2001. Functional isolation of the Candida albicans FCR3 gene encoding a bZip transcription factor homologous to Saccharomyces cerevisiae Yap3p. Yeast 18: 1217-1225.