Niflumic acid inhibits ATP-stimulated exocytosis in a mucin-secreting epithelial cell line

American Journal of Physiology - Cell Physiology

Volumn 286, Issue 2 55-2, 2004, Pages

  Bertrand, C A ^a   Danahay, H ^b   Poll, C T ^b   Laboisse, C ^c   Hopfer, U ^d   Bridges, R J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Novartis Respiratory Research Center   (United Kingdom)

^c UNIVERSITÉ DE NANTES   (France)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Capacitative calcium entry; Chloride channels; Fura 2; Membrane capacitance

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CHLORIDE; CHLORIDE CHANNEL BLOCKING AGENT; GLUCOSAMINE; MUCIN; NIFLUMIC ACID; TRITIUM;

ARTICLE; CALCIUM CELL LEVEL; CELL LINE; CELL MEMBRANE; CELL STIMULATION; CELL STRAIN HT29; CONTROLLED STUDY; ELECTRIC CAPACITANCE; ELECTRIC CURRENT; EPITHELIUM CELL; EXOCYTOSIS; HUMAN; HUMAN CELL; ISOTOPE LABELING; PATCH CLAMP; PRIORITY JOURNAL;

TRITIUM;

EID: 0742305453     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00593.2002     Document Type: Article

References (39)

1. Augeron C and Laboisse CL. Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. Cancer Res 44: 3961-3969, 1984.
2. Augeron C, Voisin T, Maoret JJ, Berthon B, Laburthe M, and Laboisse CL. Neurotensin and neuromedin N stimulate mucin output from human goblet cells (Cl.16E) via neurotensin receptors. Am J Physiol Gastrointest Liver Physiol 262: G470-G476, 1992.
3. Banderali U, Brochiero E, Lindenthal S, Raschi C, Bogliolo S, and Ehrenfeld J. Control of apical membrane chloride permeability in the renal A6 cell line by nucleotides. J Physiol 519: 737-751, 1999.
4. 2+ signals. J Cell Sci 114: 2213-2222, 2001.
5. Clapham DE, Runnels LW, and Strubing C. The TRP ion channel family. Nature Reviews 2: 387-396, 2001.
6. Davis CW. Regulation of mucin secretion from in vitro cellular models. In: Mucus Hypersecretion In Respiratory Disease, edited by Chadwick DJ and Goode JA. Chichester: John Wiley and Sons, 2002, p. 292.
7. Forstner G. Signal transduction, packaging and secretion of mucins. Annu Rev Physiol 57: 585-605, 1995.
8. - conductance in the apical membrane of murine tracheal epithelial cells. J Biol Chem 275: 35028-35033, 2000.
9. Griffin A, Newman TM, and Scott RH. Electrophysiological and ultrastructural events evoked by methacholine and intracellular photolysis of caged compounds in cultured ovine trachea submucosal gland cells. Exp Physiol 81: 27-43, 1996.
10. 2+ in HT29-Cl.16E. Am J Physiol Cell Physiol 269: C1457-C1463, 1995.
11. - conductance in HT29-Cl.16E. Am J Physiol Cell Physiol 273: C804-C809, 1997.
12. Hille B, Billiard J, Babcock DF, Nguyen T, and Koh DS. Stimulation of exocytosis without a calcium signal. J Physiol 520: 23-31, 1999.
13. Hogg RC, Wang Q, and Large WA. Action of niflumic acid on evoked and spontaneous calcium-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein. Br J Pharmacol 112: 977-984, 1994.
14. - channel I (CaCCI) gene in the asthmatic airway. Am J Respir Crit Care Med 165: 1132-1136, 2002.
15. Hwang TH, Schwiebert EM, and Guggino WB. Apical and basolateral ATP stimulates tracheal epithelial chloride secretion via multiple purinergic receptors. Am J Physiol Cell Physiol 270: C1611-C1623, 1996.
16. Jentsch TJ, Stein V, Weinreich F, and Zdebik AA. Molecular structure and physiological function of chloride channels. Physiol Rev 82: 503-568, 2002.
17. Kato K, Evans MA, and Kozlowski RZ. Relaxation of endothelin-1-induced pulmonary arterial constriction by niflumic acid and NPPB: mechanism(s) independent of chloride channel block. J Pharmacol Exp Ther 288: 1242-1250, 1999.
18. - channel activation in secretory cells. Annu Rev Physiol 62: 493-513, 2000.
19. Leverkoehne I and Gruber AD. The murine mCLCA3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cells. J Histochem Cytochem 50: 829-838, 2002.
20. Merlin D, Augeron C, Tien XY, Guo X, Laboisse CL, and Hopfer U. ATP-stimulated electrolyte and mucin secretion in the human intestinal goblet cell line HT29-Cl.16E. J Membr Biol 137: 137-149, 1994.
21. - channels from granule membrane to plasma membrane. Am J Physiol Cell Physiol 271: C612-C619, 1996.
22. Miralles F, Marsal J, Peres J, and Solsona C. Niflumic acid-induced increase in potassium currents in frog motor nerve terminals: effects on transmitter release. Brain Res 714: 192-200, 1996.
23. Nabel C, Schweda F, Riegger GAJ, Kramer BK, and Kurtz A. Chloride channel blockers attenuate the inhibition of renin secretion by angiotensin II. Pfügers Arch 438: 694-699, 1999.
24. Ottolia M and Toro L. Potentiation of large conductance KCa channels by niflumic, flufenamic and mefenamic acids. Biophys J 67: 2272-2279, 1994.
25. Putney JW Jr. The pharmacology of capacitative calcium entry. Molecular Interventions 1: 85-94, 2001.
26. Putney JW Jr, Broad LM, Braun FJ, Lievremont JP, and Bird GSJ. Mechanisms of capacitative calcium entry. J Cell Sci 114: 2223-2229, 2001.
27. - channel blockers inhibits secretion from rat mucosal-type mast cells. Mol Pharmacol 47: 1014-1020, 1995.
28. Roberts-Thomson EL, Palmer SM, Powis DA, and Bunn SJ. Histamine-stimulated phospholipase C activity in bovine adrenal medullary chromaffin cells: the effect of chloride-channel antagonists and low extracellular chloride concentrations. Neurosci Lett 278: 93-96, 2000.
29. Rohlicek V and Schmid A. Dual-frequency method for synchronous measurement of cell capacitance, membrane conductance and access resistance on single cells. Pfügers Arch 428: 30-38, 1994.
30. Specian RD and Oliver MG. Functional biology of intestinal goblet cells. Am J Physiol Cell Physiol 260: C183-C193, 1991.
31. Stewart GS, Glanville M, Aziz O, Simmons NL, and Gray MA. Regulation of an outwardly rectifying chloride conductance in renal epithelial cells by external and internal calcium. J Membr Biol 180: 49-64, 2001.
32. Stutts MJ, Fitz JG, Paradiso AM, and Boucher RC. Multiple modes of regulation of airway epithelial chloride secretion by extracellular ATP. Am J Physiol Cell Physiol 267: C1442-C1451, 1994.
33. Sun F, Hug MJ, Bradbury NA, and Frizzell RA. Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin. J Biol Chem 275: 14360-14366, 2000.
34. Teixeira MCL, Coelho RR, Leal-Cardoso JH, and Criddle DN. Comparative effects of niflumic acid and nifedipine on 5-hydroxytrytarmine-and acetylcholine-induced contraction of the rat trachea. Eur J Pharmacol 394: 117-122, 2000.
35. --permeable conductance and a CLCA protein from rat pancreatic zymogen granules. Biochem Biophys Res Commun 300: 546-554, 2003.
36. Thompson RE, Lindau M, and Webb WW. Robust, high-resolution, whole cell patch-clamp capacitance measurements using square wave stimulation. Biophys J 81: 937-948, 2001.
37. - channels in Xenopus oocytes. Mol Pharmacol 37: 720-724, 1990.
38. Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, and Matsuda Y. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 268: 25846-25856, 1993.
39. - currents activated by extracellular nucleotides in human bronchial cells. J Membr Biol 156: 297-305, 1997.