Interleukin 1β Gene Polymorphism Association with Severe Renal Manifestations and Renal Sequelae in Henoch-Schönlein Purpura

Journal of Rheumatology

Volumn 31, Issue 2, 2004, Pages 295-298

  Amoli, Mahsa M ^a   Calviño, Maria C ^b   Garcia Porrua, Carlos ^c   Llorca, Javier ^d   Ollier, William E R ^a   Gonzalez Gay, Miguel A ^c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b Pediatrics Division

^c HOSPITAL XERAL CALDE   (Spain)

^d UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Disease susceptibility; Henoch Sch nlein purpura; IL 1 gene ( 511 C T) polymorphism; Renal sequelae; Severe nephritis

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 1;

ADULT; ALLELE; ANAPHYLACTOID PURPURA; ARTICLE; CAUCASIAN; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE COURSE; DISEASE SEVERITY; DNA POLYMORPHISM; GENE; GENOTYPE; HUMAN; INCIDENCE; INTERLEUKIN 1BETA GENE; KIDNEY DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SPAIN; VASCULITIS; CHILD; DISEASE PREDISPOSITION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; NEPHRITIS;

ADULT; CHILD; DISEASE SUSCEPTIBILITY; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOTYPE; HUMANS; INCIDENCE; INTERLEUKIN-1; NEPHRITIS; POLYMORPHISM, GENETIC; PURPURA, SCHOENLEIN-HENOCH;

EID: 0742305104     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Gonzalez-Gay MA, Garcia-Porrua C. Henoch-Schönlein purpura. In: Ball GV and Bridges SL, editors. Vasculitis. New York: Oxford University Press; 2002:476-94.
2. Nicklin MJ, Weith A, Duff GW. A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes. Genomics 1994;19:382-4.
3. Mantovani A, Dejana E. Cytokines as communication signals between leukocytes and endothelial cells. Immunol Today 1989;10:370-5.
4. Krishnaswamy G, Kelley J, Yerra L, Smith JK, Chi DS. Human endothelium as a source of multifunctional cytokines: molecular regulation and possible role in human disease. J Interferon Cytokine Res 1999;19:91-104.
5. Marceau F, Grassi J, Frobert Y, Bergeron C, Poubelle PE. Effects of experimental conditions on the production of interleukin-1 alpha and -1 beta by human endothelial cells cultured in vitro. Int J Immunopharmacol 1992;14:525-34.
6. Besbas N, Saatci U, Ruacan S, et al. The role of cytokines in Henoch Schonlein purpura. Scand J Rheumatol 1997;26:456-60.
7. Hirayama K, Kobayashi M, Muro K, Yoh K, Yamagata K, Koyama A. Specific T-cell receptor usage with cytokinemia in Henoch-Schonlein purpura nephritis associated with Staphylococcus aureus infection. J Intern Med 2001;249:289-95.
8. Di Giovine FS, Takhsh E, Blakemore AI, Duff GW. Single base polymorphism at -511 in the human interleukin-1 beta gene (IL1 beta). Hum Mol Genet 1992;1:450.
9. Bidwell J, Keen L, Gallagher G, et al. Cytokine gene polymorphism in human disease: on-line databases. Genes Immun 2001;2 Suppl 1:61-70.
10. Michel BA, Hunder GG, Bloch DA, Calabrese LH. Hypersensitivity vasculitis and Henoch-Schönlein purpura: A comparison between the 2 disorders. J Rheumatol 1992;19:721-8.
11. Amoli MM, Thomson W, Hajeer AH, et al. Interleukin-1 receptor antagonist gene polymorphism is associated with severe renal involvement and renal sequelae in Henoch-Schönlein purpura. J Rheumatol 2002;29:1404-7.
12. Cox A, Camp NJ, Nicklin MJ, di Giovine FS, Duff GW. An analysis of linkage disequilibrium in the interleukin-1 gene cluster, using a novel grouping method for multiallelic markers. Am J Hum Genet 1998;62:1180-8.
13. Hurme M, Santtila S. IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1RA and IL-1beta genes. Eur J Immunol 1998;28:2598-602.
14. Carter DB, Deibel MR Jr, Dunn CJ, et al. Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein. Nature 1990;344:633-8.
15. Atkins RC. Interleukin-1 in crescentic glomerulonephritis. Kidney Int 1995;48:576-86.
16. Santos NM, Ault BH, Gharavi AG, et al. Angiotensin-converting enzyme genotype and outcome in pediatric IgA nephropathy. Pediatr Nephrol 2002;17:496-502.
17. Matsunaga A, Numakura C, Kawakami T, et al. Association of the uteroglobin gene polymorphism with IgA nephropathy. Am J Kidney Dis 2002;39:36-41.
18. Tuglular S, Berthoux P, Berthoux F. Polymorphisms of the tumour necrosis factor alpha gene at position -308 and TNFd microsatellite in primary IgA nephropathy. Nephrol Dial Transplant 2003;18:724-31.
19. Syrjanen J, Hurme M, Lehtimaki T, Mustonen J, Pasternack A. Polymorphism of the cytokine genes and IgA nephropathy. Kidney Int 2002;61:1079-85.
20. Masutani K, Miyake K, Nakashima H, et al. Impact of interferon-gamma and interleukin-4 gene polymorphisms on development and progression of IgA nephropathy in Japanese patients. Am J Kidney Dis 2003;41:371-9.
21. Casanueva B, Rodriguez-Valverde V, Luceno A. Circulating IgA producing cells in the differential diagnosis of Henoch-Schönlein purpura. J Rheumatol 1988;15:1229-33.