Enhanced expression of neurotrophic factors by C6 rat glioma cells after transfection with glia maturation factor

Neuroscience Letters

Volumn 265, Issue 3, 1999, Pages 203-206

  Zaheer, Asgar ^a   Weiss, Jessica L ^a   Goyal, Pravesh ^a   Lim, Ramon ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Brain derived neurotrophic factor; C6; Glia maturation factor; Nerve growth factor; Neurotrophic factors; PC12

Indexed keywords

MATURATION PROMOTING FACTOR; NEURITE PROMOTING FACTOR; NEUROTROPHIC FACTOR; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CELL MATURATION; CELL STRAIN; CELLULAR DISTRIBUTION; CULTURE MEDIUM; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLIOMA CELL; NERVE CELL GROWTH; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; TISSUE DISTRIBUTION;

ADENOVIRIDAE; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CULTURE MEDIA, CONDITIONED; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE EXPRESSION REGULATION, VIRAL; GLIA MATURATION FACTOR; GLIOMA; GROWTH INHIBITORS; LAC OPERON; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURITES; NEURONS; PC12 CELLS; RATS; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033597345     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00253-0     Document Type: Article

References (16)

1. Asai K., Fujita K., Yamamoto M., Hotta T., Morikawa M., Kokubo M., Moriyama A., Kato T. Isolation of novel human cDNA homologous to glia maturation factor gene. Biochim. Biophys. Acta. 1396:1998;242-244.
2. Davidson B.L., Allen E.D., Kozarsky K.F., Wilson J.M., Roessler B.J. A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nat. Genet. 3:1993;219-223.
3. Kaplan R., Zaheer A., Jaye M., Lim R. Molecular cloning and expression of biologically active human glia maturation factor beta. J. Neurochem. 57:1991;483-490.
4. Lim R., Miller J.F., Zaheer A. Purification and characterization of glia maturation factor beta: a growth regulator for neurons and glia. Proc. Natl. Acad. Sci. USA. 86:1989;3901-3905.
5. Lim R., Zaheer A., Lane W.S. Complete amino acid sequence of bovine glia maturation factor beta. Proc. Natl. Acad. Sci. USA. 87:1990;5233-5237.
6. Lim R., Zaheer A. Phorbol ester stimulates rapid intracellular phosphorylation of glia maturation factor. Biochem. Biophys. Res. Commun. 211:1995;928-934.
7. Lim R., Zaheer A. In vitro enhancement of p38 MAP kinase activity by phosphorylated glia maturation factor (GMF). J. Biol. Chem. 271:1996;22953-22956.
8. Lim R., Zaheer A., Kraakevik J.A., Darby C.J., Oberley L.W. Overexpression of glia maturation factor in C6 cells promotes differentiation and activates superoxide dismutase. Neurochem. Res. 23:1998;1445-1451.
9. Liu L.X., Xu H., Weller P.F., Shi A., Debnath I. Structure and expression of a novel filarial gene for glia maturation factor. Gene. 186:1997;1-5.
10. Nieto-Sampedro M., Lim R., Hicklin D.J., Cotman C.S. Early release of glia maturation factor and acidic fibroblast growth factor after rat brain injury. Neurosci. Lett. 86:1988;361-365.
11. Wang B.R., Zaheer A., Lim R. Polyclonal antibody localizes glia maturation factor beta-like immunoreactivity in neurons and glia. Brain Res. 591:1992;1-7.
12. Zaheer A., Fink B.D., Lim R. Expression of glia maturation factor beta mRNA and protein in rat organs and cells. J. Neurochem. 60:1993;914-920.
13. Zaheer A., Zhong W., Uc E.Y., Moser D.R., Lim R. Expression of mRNAs of multiple growth factors and receptors by astrocytes and glioma cells: detection with reverse transcription-polymerase chain reaction. Cell. Mol. Neurobiol. 15:1995;221-237.
14. Zaheer A., Lim R. In vitro inhibition of MAP kinase (ERK1/ERK2) activity by phosphorylated glia maturation factor (GMF). Biochemistry. 35:1996;6283-6288.
15. Zaheer A., Lim R. Protein kinase A (PKA)- and protein kinase C-phosphorylated glia maturation factor promotes the catalytic activity of PKA. J. Biol. Chem. 272:1997;5183-5186.
16. Zaheer A., Lim R. Overexpression of glia maturation factor (GMF) in PC12 pheochromocytoma cells activates p38 MAP kinase, MAPKAP kinase-2, and tyrosine hydroxylase. Biochem. Biophys. Res. Commun. 250:1998;278-282.