Functional and Anatomical Effects of Hormonally Induced Experimental Prostate Growth: A Urodynamic Model of Benign Prostatic Hyperplasia (BPH) in the Beagle

Prostate

Volumn 58, Issue 2, 2004, Pages 156-163

  Yokota, Takeshi ^a   Honda, K ^a   Tsuruya, Y ^a   Nomiya, M ^a   Yamaguchi, Osamu ^a   Gotanda, K ^a   Constantinou, Christos E ^b  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Functional obstruction; Micturition; Urinary tract

Indexed keywords

ANDROSTANOLONE; ESTRADIOL; HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER OBSTRUCTION; CONTROLLED STUDY; DETRUSOR MUSCLE; DOG; FUNCTIONAL ANATOMY; MALE; MICTURITION; NONHUMAN; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; SYMPTOMATOLOGY; URETHRA OBSTRUCTION; URINE FLOW RATE; URODYNAMICS;

AGE FACTORS; ANDROGENS; ANIMALS; DIHYDROTESTOSTERONE; DISEASE MODELS, ANIMAL; ESTRADIOL; HUMANS; MALE; PRESSURE; PROSTATIC HYPERPLASIA; URETHRAL OBSTRUCTION; URINATION DISORDERS; URODYNAMICS;

EID: 0742270344     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.10318     Document Type: Article

References (32)

1. Thomas AW, Abrams P. Lower urinary tract symptoms, benign prostatic obstruction and the overactive bladder. BJU Int 2000;85:57-68.
2. Sullivan MP, Yalla SV. Detrusor contractility and compliance characteristics in adult male patients with obstructive and non obstructive voiding dysfunction. J Urol 1996;155:1955-2000.
3. Rosier PF, de Wildt MJ, Wijkstra H, Debruyne FF, de la Rosette JJ. Clinical diagnosis of bladder outlet obstruction in patients with benign prostatic enlargement and lower urinary tract symptoms: Development and urodynamic validation of a clinical prostate score for the objective diagnosis of bladder outlet obstruction. J Urol 1996;155:1649-1654.
4. de la Rosette JJ, Witjes WP, Schafer W, Abrams P, Donovan JL, Peters TJ, Millard RJ, Frimodt-Moller C, Kalomiris P. Relationships between lower urinary tract symptoms and bladder outlet obstruction. Neurourol Urodyn 1998;17:99-108.
5. Blaivas JG. Pathophysiology and differential diagnosis of BPH. Urology 1988;32(Suppl 6):5-11.
6. Mills IW, Greenland JE, McMurray G, McCoy R, Ho KM, Noble JG, Brading AF. Studies of the pathophysiology of idiopathic detrusor instability; the physiological properties of the detrusor smooth muscle and its patterns of innervation. J Urol 2000;163:646-651.
7. Speakman MJ, Brading AF, Gilpin CJ, Dixon JS, Gilpin SA, Gosling JA. Bladder outflow obstruction-A cause of denervation super-sensitivity. J Urol 1987;138:1461-1466.
8. Speakman MJ, Brading AF, Dixon JS, Gilpin SA, Gosling JA. Cystometric physiological and morphological studies after relief of bladder outflow obstruction in the pig. Brit J Urol 1991;68:243-247.
9. Dixon JS, Gilpin CJ, Gosling JA, Brading AF, Speakman MJ. Sequential morphological changes in the pig detrusor in response to chronic urethral obstruction. Brit J Urol 1989;64:385-390.
10. Maggi CA, Manzini S, Giuliani S, Meli S. Infravesical outflow obstruction in rats: A comparison of two models. General Pharmacol 1986;20:345-349.
11. Constantinou CE. Influence of hormone treatment on prostate growth and micturition characteristics of the rat. Prostate 1996;29:30-35.
12. Constantinou CE, Omata S. Analysis of the relative biomechanical effects of alpha 1 and alpha 2 antagonists in modifying the compliance of the prostate and micturition parameters of the hormonally manipulated rat. Neurourol Urodyn 1996;15:85-101.
13. Lee JZ, Tillig B, Perkash I, Constantinou CE. Effect of alpha 1 adrenoceptor antagonist on the urodynamics of the upper and lower urinary tract of the male rat. Neurourol Urodyn 1998;17:213-229.
14. Pandita RK, Persson K, Hedlund P, Andersson KE. Testosterone induced prostatic growth in the rat cases hyperactivity unrelated to detrusor hypertrophy. Prostate 1998;35:102-108.
15. Coffey DS, Walsh PC. Clinical and experimental studies of benign prostatic hyperplasia. Urol Clin North Am 1990;17:461-475.
16. Takezawa Y, Fukabori Y, Yamanaka H, Mieda M, Honma S, Kushitan M, Hamataki N. Effects of the new steroidal antiandrogen TZP-4238 on hormone-induced canine prostatic hyperplasia. Prostate 1992;21:315-329.
17. Winter ML, Bosland MC, Wade DR, Falvo RE, Nagamani M, Liehr JG. Induction of benign prostatic hyperplasia in intact dogs by near physiological levels of 5 alpha-dihydroterstosterone and 17 beta-estradiol. Prostate 1995;26:325-333.
18. Schmidt F, Shin P, Jorgensen TM, Djurhuus JC, Constantinou CE. Urodynamic patterns of normal male micturition: Influence of water consumption on urine production and detrusor function. J Urol 2002;168:1458-1463.
19. Constantinou CE, Damaser MS, Perkash I. Displacement sequence and elastic properties of anterior prostate/urethral interface during micturition of spinal cord injured men. Ultrasound Med Biol 2002;28:1157-1163.
20. Broderick GA, Longhurst PA, Juniewicz PE, Wein AJ, Levin RM. A novel canine model of partial outlet obstruction secondary to prostatic hypertrophy. World J Urol 1994;2:245-248.
21. Hildebrand RK, Naslund MJ, Oesterling JE, Coffey DS. Influence of age, strain, and the testes on rat prostate hormone sensitivity. Prostate 1991;18:81-89.
22. Yokota T, Constantinou CE. Hormonally induced changes in the regulation of lower urinary tract receptors of the male rat. Neurourol Urodyn 1997;16:388-390.
23. Choo M-S, Constantinou CE. Prostate growth restraint of alpha1 ADR agonists and antagonists to DHT-induced prostate growth. Neurourol Urodyn 2001;20:474-475.
24. Yoshimura Y, Choo M-S, Bellamy F. Constantinou comparative influence of TAD and antagonists to DHT-induced prostate growth. Neurourol Urodyn 2001;20:476-477.
25. Keast JR, Saunders RJ. Testosterone has potent, selective effects on the morphology of pelvic autonomic neurons which control the bladder, lower bowel, and internal reproductive organs of the male rat. Neuroscience 1998;85:543-556.
26. Diep N, Constantinou CE. Age dependent response to exogenous estrogen on micturition, contractility and cholinergic receptors of the rat's bladder. Life Sci 1999;6:279-289.
27. Palea S, Angel I. The effect of ovariectomy on the contractile response of the rat isolated detrusor muscle and urethra. Life Sci 1997;61:21-26.
28. Hegde SS, Eglen RM. Muscarinic receptor subtypes modulating smooth muscle contractility in the urinary bladder. Life Sci 1999;64:419-428.
29. Homma Y, Hamada K, Nakayama Y, Tsujimoto G, Kawabe K. Effects on contraction and alpha1 adrenoceptor expression in the rat. British J Pharmacol 2000;131:1434-1460.
30. Iwata T, Ukimura O, Inaba M, Kojima M, Kumamoto K, Ozawa H, Kawata M, Tsuneharu K. Immunohistochemical studies on the distribution of nerve fibers in the human prostate with special reference to the anterior fibromuscular stroma. Prostate 2001;48:242-247.
31. Kyprianou N, Chon J, Benning CM. Effects of alpha(1)-adrenoceptor (alpha(1)-AR) antagonists on cell proliferation and apoptosis in the prostate: Therapeutic implications in prostatic disease. Prostate Suppl 2000;9:42-46.
32. Glassman DT, Chon JK, Borkowski A, Jacobs SC, Kyprianou N. Combined effect of terazosisn and dinassteride on apoptosis, cell proliferation, and transforming growth factor beta expression in BPH. Prostate 2001;46:45-51.