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Volumn 15, Issue 6, 2003, Pages 761-765

Evaluation and management of pulmonary hypertension in systemic sclerosis

Author keywords

Diagnosis; Markers; Pathophysiology; Pulmonary hypertension; Systemic sclerosis

Indexed keywords

BOSENTAN; ENDOTHELIN RECEPTOR ANTAGONIST; MARKER; PROSTACYCLIN; SILDENAFIL; SITAXSENTAN; UNIPROST;

EID: 0742269647     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002281-200311000-00013     Document Type: Review
Times cited : (14)

References (32)
  • 1
    • 0022600374 scopus 로고
    • Pulmonary hypertension in the CREST syndrome variant of systemic sclerosis
    • Stupi AM, Steen VD, Owens GR, et al.: Pulmonary hypertension in the CREST syndrome variant of systemic sclerosis. Arthritis Rheum 1986, 29:515-524.
    • (1986) Arthritis Rheum , vol.29 , pp. 515-524
    • Stupi, A.M.1    Steen, V.D.2    Owens, G.R.3
  • 2
    • 0020520743 scopus 로고
    • Prevalence and clinical correlates of pulmonary arterial hypertension in progressive systemic sclerosis
    • Ungerer RG, Tashkin DP, Furst D, et al.: Prevalence and clinical correlates of pulmonary arterial hypertension in progressive systemic sclerosis. Am J Med 1983, 75:65-74, 3
    • (1983) Am J Med , vol.75 , pp. 65-74
    • Ungerer, R.G.1    Tashkin, D.P.2    Furst, D.3
  • 3
    • 0017619874 scopus 로고
    • Pulmonary hypertension in the CREST syndrome variant of progressive systemic sclerosis (systemic sclerosis)
    • Salerni R, Rodnan GP, Leon DF, et al.: Pulmonary hypertension in the CREST syndrome variant of progressive systemic sclerosis (systemic sclerosis). Ann Intern Med 1977, 86:394-399.
    • (1977) Ann Intern Med , vol.86 , pp. 394-399
    • Salerni, R.1    Rodnan, G.P.2    Leon, D.F.3
  • 4
    • 0000066864 scopus 로고    scopus 로고
    • Systemic sclerosis and related syndromes: Clinical features
    • Edited by Klippel JHCL, Stone JH, Weyand CM. Atlanta: Atlanta Arthritis Foundation
    • Steen V: Systemic sclerosis and related syndromes: clinical features. In Primer on Rheumatic Diseases. Edited by Klippel JHCL, Stone JH, Weyand CM. Atlanta: Atlanta Arthritis Foundation; 1997:267-272.
    • (1997) Primer on Rheumatic Diseases , pp. 267-272
    • Steen, V.1
  • 5
    • 0019462870 scopus 로고
    • Idiopathic pulmonary fibrosis clinical conference
    • Campbell E, Harris B: Idiopathic pulmonary fibrosis clinical conference. Arch Intern Med 1981, 141:771-774.
    • (1981) Arch Intern Med , vol.141 , pp. 771-774
    • Campbell, E.1    Harris, B.2
  • 6
    • 0036300827 scopus 로고    scopus 로고
    • Post-menopause is the main risk factor for developing isolated pulmonary hypertension in systemic sclerosis
    • Scorza R, Caronni M, Bazzi S, et al.: Post-menopause is the main risk factor for developing isolated pulmonary hypertension in systemic sclerosis. Ann N Y Acad Sci 2002, 966:238-246.
    • (2002) Ann N Y Acad Sci , vol.966 , pp. 238-246
    • Scorza, R.1    Caronni, M.2    Bazzi, S.3
  • 7
    • 0037331671 scopus 로고    scopus 로고
    • Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement
    • Steen V, Medsger TA Jr: Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement. Arthritis Rheum 2003, 48:516-522.
    • (2003) Arthritis Rheum , vol.48 , pp. 516-522
    • Steen, V.1    Medsger Jr., T.A.2
  • 8
    • 0023684923 scopus 로고
    • The nuclear matrix protein, numatrin (B23), is associated with growth factor-induced mitogenesis in Swiss 3T3 fibroblasts and with T lymphocyte proliferation stimulated by lectins and anti-T cell antigen receptor antibody
    • Feuerstein N, Spiegel S, Mond J: The nuclear matrix protein, numatrin (B23), is associated with growth factor-induced mitogenesis in Swiss 3T3 fibroblasts and with T lymphocyte proliferation stimulated by lectins and anti-T cell antigen receptor antibody. J Cell Biol 1988, 107:1629-1642.
    • (1988) J Cell Biol , vol.107 , pp. 1629-1642
    • Feuerstein, N.1    Spiegel, S.2    Mond, J.3
  • 9
    • 0026579621 scopus 로고
    • Nucleolar antigens and autoantibodies in hepatocellular carcinoma and other malignancies
    • Imai H, Ochs R, Kiyosawa K, et al.: Nucleolar antigens and autoantibodies in hepatocellular carcinoma and other malignancies. Am J Pathol 1992, 140: 859-870.
    • (1992) Am J Pathol , vol.140 , pp. 859-870
    • Imai, H.1    Ochs, R.2    Kiyosawa, K.3
  • 10
    • 0037440854 scopus 로고    scopus 로고
    • Autoantibodies against B23, a nucleolar phosphoprotein, occur in systemic sclerosis and are associated with pulmonary hypertension
    • Ulanet DB, Wigley FM, Gelber AC, et al.: Autoantibodies against B23, a nucleolar phosphoprotein, occur in systemic sclerosis and are associated with pulmonary hypertension. Arthritis Rheum 2003, 49:85-92. This study describes a novel antibody that is increased in systemic sclerosis patients with lung involvement.
    • (2003) Arthritis Rheum , vol.49 , pp. 85-92
    • Ulanet, D.B.1    Wigley, F.M.2    Gelber, A.C.3
  • 11
    • 0037295439 scopus 로고    scopus 로고
    • Plasma plasmin-alpha2-plasmin inhibitor complex levels are increased in systemic sclerosis patients with pulmonary hypertension
    • Oxford
    • Jinnin M, Ihn H, Yamane K, et al.: Plasma plasmin-alpha2-plasmin inhibitor complex levels are increased in systemic sclerosis patients with pulmonary hypertension. Rheumatology (Oxford) 2003, 42:240-243.
    • (2003) Rheumatology , vol.42 , pp. 240-243
    • Jinnin, M.1    Ihn, H.2    Yamane, K.3
  • 12
    • 0036262665 scopus 로고    scopus 로고
    • CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse
    • Saito E, Fujimoto M, Hasegawa M, et al.: CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse. J Clin Invest 2002, 109:1453-1462.
    • (2002) J Clin Invest , vol.109 , pp. 1453-1462
    • Saito, E.1    Fujimoto, M.2    Hasegawa, M.3
  • 13
    • 0036844311 scopus 로고    scopus 로고
    • Pulmonary hypertension in systemic sclerosis spectrum of disease: Lack of bone morphogenetic protein receptor 2 mutations
    • Morse J, Barst R, Horn E, et al.: Pulmonary hypertension in systemic sclerosis spectrum of disease: lack of bone morphogenetic protein receptor 2 mutations. J Rheumatol 2002, 29:2379-2381. This study outlines the genetic differences between PPH and PAH related to systemic sclerosis.
    • (2002) J Rheumatol , vol.29 , pp. 2379-2381
    • Morse, J.1    Barst, R.2    Horn, E.3
  • 14
    • 0022355748 scopus 로고
    • Continuous wave Doppler determination of right ventricular pressure: A simultaneous Doppler-catheterization study in 127 patients
    • Currie P, Seward J, Chan K, et al.: Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler- catheterization study in 127 patients. J Am Coll Cardiol 1985, 6:750-756.
    • (1985) J Am Coll Cardiol , vol.6 , pp. 750-756
    • Currie, P.1    Seward, J.2    Chan, K.3
  • 15
    • 0037364372 scopus 로고    scopus 로고
    • Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease
    • Arcasoy S, Christie J, Ferrari V, et al.: Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease. Am J Respir Crit Care Med 2003, 167:735-740. This important study demonstrates that echocardiography can often over-and underestimate PA pressures in patients with advanced lung disease.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 735-740
    • Arcasoy, S.1    Christie, J.2    Ferrari, V.3
  • 16
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
    • The Primary Pulmonary Hypertension Study Group
    • Barst RJ, Rubin LJ, Long WA, et al.: A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N Engl J Med 1996, 334:296-302.
    • (1996) N Engl J Med , vol.334 , pp. 296-302
    • Barst, R.J.1    Rubin, L.J.2    Long, W.A.3
  • 17
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the systemic sclerosis spectrum of disease. A randomized, controlled trial
    • Badesch DB, Tapson VF, McGoon MD, et al.: Continuous intravenous epoprostenol for pulmonary hypertension due to the systemic sclerosis spectrum of disease. A randomized, controlled trial. Ann Intern Med 2000, 132:425-434.
    • (2000) Ann Intern Med , vol.132 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3
  • 18
    • 0037086133 scopus 로고    scopus 로고
    • Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertensions double-blind, randomized, placebo-controlled trial
    • Simonneau G, Barst R, Galie N, et al.: Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertensions double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 2002, 165:800-804.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 800-804
    • Simonneau, G.1    Barst, R.2    Galie, N.3
  • 19
    • 0028029736 scopus 로고    scopus 로고
    • Circulating endothelin-1 levels in systemic sclerosis subsets-a marker of fibrosis or vascular dysfunction?
    • Vancheeswaran R, Magoulas T, Efrat G, et al.: Circulating endothelin-1 levels in systemic sclerosis subsets-a marker of fibrosis or vascular dysfunction? J Rheumatol 1996, 21:1838-1844.
    • (1996) J Rheumatol , vol.21 , pp. 1838-1844
    • Vancheeswaran, R.1    Magoulas, T.2    Efrat, G.3
  • 20
    • 0027324745 scopus 로고
    • Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
    • Giaid A, Yanagisawa M, Langleben D, et al.: Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med 1993, 328: 1732-1739.
    • (1993) N Engl J Med , vol.328 , pp. 1732-1739
    • Giaid, A.1    Yanagisawa, M.2    Langleben, D.3
  • 21
    • 0033110922 scopus 로고    scopus 로고
    • Localization and distribution of endothelin receptor subtypes in pulmonary vasculature of normal and hypoxia-exposed rats
    • Soma S, Takahashi H, Muramatsu M, et al.: Localization and distribution of endothelin receptor subtypes in pulmonary vasculature of normal and hypoxia-exposed rats. Am J Respir Cell Mol Biol 1999, 20:620-630.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 620-630
    • Soma, S.1    Takahashi, H.2    Muramatsu, M.3
  • 22
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • Rubin LJ, Badesch DB, Barst RJ, et al.: Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 2002, 346:896-903. This study establishes the efficacy of nonselective endothelin receptor antagonist bosentan on functional capacity in patients with different forms of PAH.
    • (2002) N Engl J Med , vol.346 , pp. 896-903
    • Rubin, L.J.1    Badesch, D.B.2    Barst, R.J.3
  • 23
    • 0037484589 scopus 로고    scopus 로고
    • Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension: A 1 -year follow-up study
    • Sitbon O, Badesch D, Channick R, et al.: Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension: a 1 -year follow-up study. Chest 2003, 124:247-254. This open-label trial shows the long-term effects of bosentan in patients with PAH.
    • (2003) Chest , vol.124 , pp. 247-254
    • Sitbon, O.1    Badesch, D.2    Channick, R.3
  • 24
    • 0036283401 scopus 로고    scopus 로고
    • Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension: Open-label pilot study
    • Barst R, Rich S, Widlitz A, et al.: Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension: open-label pilot study. Chest 2002, 212:1860-1868. This study shows that sitaxsentan improved functional capacity in PAH patients.
    • (2002) Chest , vol.212 , pp. 1860-1868
    • Barst, R.1    Rich, S.2    Widlitz, A.3
  • 25
    • 0242324585 scopus 로고    scopus 로고
    • Sitaxsentan, a selective ETA antagonist, improves hemodynamics in pulmonary arterial hypertension (PAH)
    • abstract
    • Barst R, Langleben D, Frost A, et al.: Sitaxsentan, a selective ETA antagonist, improves hemodynamics in pulmonary arterial hypertension (PAH). Am J Respir Crit Care Med 2003, 167:A273 (abstract).
    • (2003) Am J Respir Crit Care Med , vol.167
    • Barst, R.1    Langleben, D.2    Frost, A.3
  • 26
    • 0346577301 scopus 로고    scopus 로고
    • Sitaxsentan, a selective ETA antagonist, improves exercise capacity and NYHA functional class in pulmonary arterial hypertension (PAH)
    • abstract
    • Barst R, Langleben D, Frost A, et al.: Sitaxsentan, a selective ETA antagonist, improves exercise capacity and NYHA functional class in pulmonary arterial hypertension (PAH). Am J Respir Crit Care Med 2003, 167:A440 (abstract).
    • (2003) Am J Respir Crit Care Med , vol.167
    • Barst, R.1    Langleben, D.2    Frost, A.3
  • 27
    • 0035962999 scopus 로고    scopus 로고
    • Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain
    • Giordano D, De Stefano M, Citro G, et al.: Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain. Biochim Biophys Acta 2001, 28:16-27.
    • (2001) Biochim Biophys Acta , vol.28 , pp. 16-27
    • Giordano, D.1    De Stefano, M.2    Citro, G.3
  • 28
    • 0037262909 scopus 로고    scopus 로고
    • Systemic lupus erythematosus-associated pulmonary hypertension: Good outcome following sildenafil therapy
    • Molina J, Lucero E, Luluaga S, et al.: Systemic lupus erythematosus-associated pulmonary hypertension: good outcome following sildenafil therapy. Lupus 2003, 12:321-323.
    • (2003) Lupus , vol.12 , pp. 321-323
    • Molina, J.1    Lucero, E.2    Luluaga, S.3
  • 29
    • 0035845634 scopus 로고    scopus 로고
    • Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension
    • Wilkens H, Guth A, Konig J, et al.: Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension. Circulation 2001, 104:1218-1222.
    • (2001) Circulation , vol.104 , pp. 1218-1222
    • Wilkens, H.1    Guth, A.2    Konig, J.3
  • 30
    • 0037006966 scopus 로고    scopus 로고
    • Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension
    • Ghofrani H, Wiedemann R, Rose F, et al.: Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 2002, 136:515-522.
    • (2002) Ann Intern Med , vol.136 , pp. 515-522
    • Ghofrani, H.1    Wiedemann, R.2    Rose, F.3
  • 31
    • 0037331116 scopus 로고    scopus 로고
    • Hemodynamics and survival in patients with pulmonary arterial hypertension related to systemic sclerosis
    • Kawut SM, Taichman DB, Archer-Chicko CL, et al.: Hemodynamics and survival in patients with pulmonary arterial hypertension related to systemic sclerosis. Chest 2003, 123:344-350.
    • (2003) Chest , vol.123 , pp. 344-350
    • Kawut, S.M.1    Taichman, D.B.2    Archer-Chicko, C.L.3
  • 32
    • 0037441640 scopus 로고    scopus 로고
    • Outcome in 91 consecutive patients with pulmonary arterial hypertension receiving epoprostenol
    • Kuhn KP, Byrne DW, Arbogast PG, et al.: Outcome in 91 consecutive patients with pulmonary arterial hypertension receiving epoprostenol. Am J Respir Crit Care Med 2003, 167:580-586. In this cohort study of PAH patients on epoprostenol, systemic sclerosis patients had a worse outcome compared with PPH patients.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 580-586
    • Kuhn, K.P.1    Byrne, D.W.2    Arbogast, P.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.