Biphasic pro-thrombotic and inflammatory responses after coronary artery bypass surgery

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 3, 2003, Pages 470-476

  Li, N ^a   Astudillo, R ^b   Ivert, T ^b   Hjemdahl, P ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Coronary artery bypass grafting; Inflammation; Leukocytes; Platelets; Thrombosis

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; PLASMA PROTEIN;

AGED; ARTICLE; BLOOD; CELL ADHESION; CORONARY ARTERY BYPASS GRAFT; FEMALE; HUMAN; INFLAMMATION; LEUKOCYTE; MALE; PHYSIOLOGY; THROMBOCYTE ACTIVATION; THROMBOPHILIA; TIME;

AGED; BIOLOGICAL MARKERS; BLOOD PROTEINS; CELL ADHESION; CORONARY ARTERY BYPASS; CYTOKINES; FEMALE; HUMANS; INFLAMMATION; LEUKOCYTES; MALE; PLATELET ACTIVATION; THROMBOPHILIA; TIME FACTORS;

EID: 0642372616     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.00109.x     Document Type: Article

References (19)

1. Mehta D, Izzat MB, Bryan AJ, Angelini GD. Towards the prevention of vein graft failure. Int J Cardiol 1997; 62 (Suppl. 1): S55-63.
2. Fitzgibbon GM, Kafka HP, Leach AJ, Keon WJ, Hooper GD, Burton JR. Coronary bypass graft fate and patient outcome angiographic follow-up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. J Am Coll Cardiol 1996; 28: 616-26.
3. Motwani JG, Topol EJ. Aortocoronary saphenous vein graft disease. Pathogenesis, Predisposition, Prevention Circulation 1998; 97: 916-31.
4. Chesebro JH, Clements IP, Fuster V, Elveback LR, Smith HC, Bardsley WT, Frye RL, Holmes DR Jr, Vlietstra RE, Pluth JR, Wallace RB, Puga FJ, Orszulak TA, Piehler JM, Schaff HV, Danielson GK. A plateletinhibitor-drug trial in coronary-artery bypass operations: benefit of perioperative dipyridamole and aspirin therapy on early postoperative vein-graft patency. N Engl J Med 1982; 307: 73-8.
5. Antiplatelet Trialists' Collaboration. Collaborative overview of randomised trials of antiplatelet therapy - II. Maintenance of vascular graft or arterial patency by antiplatelet therapy. BMJ 1994; 308: 159-68.
6. Weerasinghe A, Taylor KM. The platelet in cardiopulmonary bypass. Ann Thorac Surg 1998; 66: 2145-52.
7. Rinder CS, Bonan JL, Rinder HM, Mathew J, Hines R, Smith BR. Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood 1992; 79: 1201-5.
8. Asimakopoulos G, Taylor KM. Effects of cardiopulmonary bypass on leukocyte and endothelial adhesion molecules. Ann Thorac Surg 1998; 66: 2135-44.
9. Angelini GD, Bryan AJ, Williams HM, Morgan R, Newby AC. Distention promotes platelet and leukocyte adhesion and reduces shortterm patency in pig arteriovenous bypass grafts. J Thorac Cardiovasc Surg 1990; 99: 433-9.
10. Ferroni P, Speziale G, Ruvolo G, Giovannelli A, Pulcinelli FM, Lenti L, Pignatelli P, Criniti A, Tonelli E, Marino B, Gazzaniga PP. Platelet activation and cytokine production during hypothermic cardiopulmonary bypass - a possible correlation? Thromb Haemost 1998; 80: 58-64.
11. Zahler S, Massoudy P, Hartl H, Hahnel C, Meisner H, Becker BF. Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass. Cardiovasc Res 1999; 41: 722-30.
12. Li N, Soop A, Sollevi A, Hjemdahl P. Multi-cellular activation in vivo by endotoxin in humans - limited protection by adenosine infusion. Thromb Haemost 2000; 84: 381-7.
13. Li N, Halldén G, Hjemdahl P. Awhole-blood flow cytometric assay for leukocyte CD11b expression using fluorescence signal triggering. Eur J Haematol 2000; 65: 57-65.
14. Li N, Goodall AH, Hjemdahl P. Efficient flow cytometric assay for platelet-leukocyte aggregates in whole blood using fluorescence signal triggering. Cytometry 1999; 35: 154-61.
15. Reverter JC, Béguin S, Kessels H, Kumar R, Hemker HC, Coller BS. Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody. J Clin Invest 1996; 98: 863-74.
16. Li N, Wallén NH, Hjemdahl P. Evidence for prothrombotic effects of exercise and limited protection by aspirin. Circulation 1999; 100: 1374-9.
17. Esmon CT. Possible involvement of cytokines in diffuse intravascular coagulation and thrombosis. Baillières Best Pract Res Clin Haematol 1999; 12: 343-59.
18. Libman RB, Wirkowski E, Neystat M, BarrW, Gelb S, Graver M. Stroke associated with cardiac surgery. Determinants, timing, and stroke subtypes. Arch Neurol 1997; 54: 83-7.
19. Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324: 71-86.