Monitoring for hazardous drugs in the operating room [1]

Annals of Surgical Oncology

Volumn 10, Issue 7, 2003, Pages 821-822

  Connor, Thomas H ^a   Van Balen, Peter ^b   Sessink, Paul J M ^c  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c Exposure Control   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; METHANOL; MITOMYCIN C; ANTINEOPLASTIC ANTIBIOTIC; MITOMYCIN;

AIR ANALYSIS; AIR SAMPLING; ANALYTIC METHOD; CONTAMINATION; DANGEROUS GOODS; DOCUMENTATION; DRUG ELIMINATION; DRUG EXCRETION; DRUG EXPOSURE; DRUG HALF LIFE; DRUG MONITORING; DRUG URINE LEVEL; FILTER; HEALTH CARE; HEALTH CARE PERSONNEL; HEATING; HUMAN; HYGIENE; LAVAGE; LETTER; METHODOLOGY; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OCCUPATIONAL SAFETY; OPERATING ROOM; VAPORIZATION; AIR POLLUTANT; ENVIRONMENTAL MONITORING; HEAT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MANPOWER; NOTE; SAFETY; VOLATILIZATION;

AIR POLLUTANTS, OCCUPATIONAL; ANTIBIOTICS, ANTINEOPLASTIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENVIRONMENTAL MONITORING; HEAT; HUMANS; MITOMYCIN; OCCUPATIONAL EXPOSURE; OPERATING ROOMS; SAFETY MANAGEMENT; VOLATILIZATION;

EID: 0642341936     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1245/ASO.2003.03.988     Document Type: Letter

References (10)

1. Kiffmeyer TK, Kube C, Opiolka S, Schmidt KG, Schöppe G, Sessink PJM. Vapour pressures, evaporation behaviour and airborne concentrations of hazardous drugs: implications for occupational safety. Pharmaceut J 2002;268:331-7.
2. Connor TH, Shults M, Fraser MP. Determination of the vaporization of mutagenic antineoplastic agents at 23 and 37°C using a desiccator technique. Mutat Res 2000;470:85-92.
3. Stanetzek I, Giese U, Schuster RH, Wünsch G. Chromatographic characterization of adsorbents for selective sampling of organic air pollutants. Am Ind Hyg Assoc J 1996;57:128-33.
4. Larson RR, Dillon HK, Khazaeli MB. A new monitoring method using solid sorbent media for evaluation of airborne cyclophosphamide and other antineoplastic agents. Appl Occup Environ Hyg 2003;18:120-31.
5. Jacquet P, Averbach A, Stephens AD, Stuart OA, Chang D, Sugarbaker PH. Heated intraoperative intraperitoneal mitomycin C and early postoperative intraperitoneal 5-fluorouracil: pharmacokinetic studies. Oncology 1998;55:130-8.
6. Verweij J, Schellens JHM, Loo TL, Pinedo HM. Antitumor antibiotics. In: Chabner BA, Longo DL, eds. Cancer Chemotherapy and Biotherpy: Principles and Practice. 2nd ed. Philadelphia: Lippincott-Raven, 1996:395-434.
7. Physicians' Desk Reference, 1999. Montvale, NJ: Medical Economics Co, Inc., 1999.
8. Connor TH, Anderson RW, Sessink PJM, Broadfield L, Power LA. Surface contamination with antineoplastic agents in six cancer treatment centers in Canada and the United States. Am J Health-Syst Pharm 1999;56:1427-32.
9. Sessink PJM, Boer KA, Scheefhals APH, Anzion RBM, Bos RP. Occupational exposure to antineoplastic agents at several departments in a hospital: environmental contamination and excretion of cyclophosphamide and ifosfamide in urine of exposed workers. Int Arch Occup Environ Health 1992;94:105-12.
10. Pethran A, Schierl R, Hauff K, Grimm C-H, Boos K-S, Nowak D. Uptake of antineoplastic agents in pharmacy and hospital personnel. Part I: monitoring of urinary concentrations. Int Arch Occup Environ Health 2003;76:5-10.