COX-2-deficient mice are less prone to MPTP-neurotoxicity than wild-type mice

NeuroReport

Volumn 14, Issue 15, 2003, Pages 1927-1929

  Feng, Zhehui ^a,c   Li, Dongdong ^a   Fung, Peter C W ^a   Pei, Zhong ^a   Ramsden, David B ^b   Ho, Shu Leong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

COX 2; Knockout mouse. MPTP; Parkinson's disease; Substantia nigra; Tyrosine hydroxylase

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CYCLOOXYGENASE 2; TYROSINE 3 MONOOXYGENASE; DOPAMINE RECEPTOR STIMULATING AGENT; ISOENZYME; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; HETEROZYGOSITY; HUMAN; IMMUNOCOMPETENT CELL; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; SUBSTANTIA NIGRA; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; ENZYMOLOGY; GENETICS; GENOTYPE; METABOLISM; MOUSE MUTANT; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; CYCLOOXYGENASE 2; DOPAMINE AGENTS; GENOTYPE; ISOENZYMES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARKINSON DISEASE, SECONDARY; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 0642339281     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200310270-00009     Document Type: Article

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