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Volumn 14, Issue 5, 2003, Pages 654-657

New Therapies for the Management of Keloids

Author keywords

Imiquimod; Interferon; Keloid; Laser therapy

Indexed keywords

ALPHA2B INTERFERON; AMINOQUINOLINE DERIVATIVE; CORTICOSTEROID; IMIQUIMOD; IMMUNOSUPPRESSIVE AGENT; INTERFERON INDUCING AGENT; TACROLIMUS;

EID: 0642311081     PISSN: 10492275     EISSN: 15363732     Source Type: Journal    
DOI: 10.1097/00001665-200309000-00009     Document Type: Article
Times cited : (49)

References (47)
  • 1
  • 2
    • 17444374137 scopus 로고    scopus 로고
    • Keloidal scars: a review with a critical look at therapeutic options.
    • Shaffer JJ, Taylor SC, Cook-Bolden F. Keloidal scars: a review with a critical look at therapeutic options. J Am Acad Dermatol 2002; 46(Suppl):S63
    • (2002) J Am Acad Dermatol , vol.46 , pp. S63
    • Shaffer, J.J.1    Taylor, S.C.2    Cook-Bolden, F.3
  • 3
    • 85026145828 scopus 로고    scopus 로고
    • Keloid and hypertrophic scar.
    • Berman B, Kapoor S. Keloid and hypertrophic scar. eMedicine 2001; 2:1-12. Available at: www.emedicine.com
    • (2001) eMedicine , vol.2 , pp. 1
    • Berman, B.1    Kapoor, S.2
  • 4
    • 0026741023 scopus 로고
    • Evaluation of various methods of treating keloids and hypertrophic scars: a 10-year follow-up study.
    • Darzi MA, Chowdri NA, Kaul SK, et al. Evaluation of various methods of treating keloids and hypertrophic scars: a 10-year follow-up study. Br J Plast Surg 1992; 45:374-379
    • (1992) Br J Plast Surg , vol.45 , pp. 374
    • Darzi, M.A.1    Chowdri, N.A.2    Kaul, S.K.3
  • 5
    • 0030051516 scopus 로고    scopus 로고
    • Adjunct therapies to surgical management of keloids.
    • Berman B, Bieley HC. Adjunct therapies to surgical management of keloids. Dermatol Surg 1996; 22:126-130
    • (1996) Dermatol Surg , vol.22 , pp. 126
    • Berman, B.1    Bieley, H.C.2
  • 6
    • 0026324603 scopus 로고
    • In search of the optimal treatment of keloids: report of a series and a review of the literature.
    • Lawrence WT. In search of the optimal treatment of keloids: report of a series and a review of the literature. Ann Plast Surg 1991; 27:164-178
    • (1991) Ann Plast Surg , vol.27 , pp. 164
    • Lawrence, W.T.1
  • 8
    • 0036152289 scopus 로고    scopus 로고
    • Treatment of the keloid: what is new?
    • Porter JP. Treatment of the keloid: what is new? Otolarygol Clin North Am 2002; 35:207-220
    • (2002) Otolarygol Clin North Am , vol.35 , pp. 207
    • Porter, J.P.1
  • 9
    • 0026034235 scopus 로고
    • The effect of carbon dioxide laser surgery on the recurrence of keloids.
    • Norris JE. The effect of carbon dioxide laser surgery on the recurrence of keloids. Plast Reconstr Surg 1991; 87:44-49
    • (1991) Plast Reconstr Surg , vol.87 , pp. 44
    • Norris, J.E.1
  • 10
    • 0021269499 scopus 로고
    • Argon and carbon dioxide laser treatment of hypertrophic and keloid scars.
    • Henderson DL, Cromwell TA, Mes LG. Argon and carbon dioxide laser treatment of hypertrophic and keloid scars. Lasers Surg Med 1984; 3:271-277
    • (1984) Lasers Surg Med , vol.3 , pp. 271
    • Henderson, D.L.1    Cromwell, T.A.2    Mes, L.G.3
  • 11
    • 0024390859 scopus 로고
    • Failure of carbon dioxide laser excision of keloids.
    • Apfelberg DB, Maser MR, White DN, et al. Failure of carbon dioxide laser excision of keloids. Lasers Surg Med 1989; 9:382-388
    • (1989) Lasers Surg Med , vol.9 , pp. 382
    • Apfelberg, D.B.1    Maser, M.R.2    White, D.N.3
  • 12
    • 0020964667 scopus 로고
    • Effects of the Nd:YAG laser on DNA synthesis and collagen production in human skin fibroblast cultures.
    • Castro DJ, Abergel RP, Meeker CA, et al. Effects of the Nd:YAG laser on DNA synthesis and collagen production in human skin fibroblast cultures. Ann Plast Surg 1983; 11:214-222
    • (1983) Ann Plast Surg , vol.11 , pp. 214
    • Castro, D.J.1    Abergel, R.P.2    Meeker, C.A.3
  • 13
    • 0034191174 scopus 로고    scopus 로고
    • In situ irradiation of keloid scars with Nd:YAG laser.
    • Kumar K, Kapoor BS, Rai P, et al. In situ irradiation of keloid scars with Nd:YAG laser. J Wound Care 2000; 9:213
    • (2000) J Wound Care , vol.9 , pp. 213
    • Kumar, K.1    Kapoor, B.S.2    Rai, P.3
  • 14
    • 0028049102 scopus 로고
    • Improvement of erythematous and hypertrophic scars by the 585 nm flashlamp pulsed dye laser.
    • Alster TS. Improvement of erythematous and hypertrophic scars by the 585 nm flashlamp pulsed dye laser. Ann Plast Surg 1994; 32:186-190
    • (1994) Ann Plast Surg , vol.32 , pp. 186
    • Alster, T.S.1
  • 15
    • 0029048864 scopus 로고
    • Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser.
    • Alster TS, Williams CM. Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser. Lancet 1995; 345:1198-2000
    • (1995) Lancet , vol.345 , pp. 1198
    • Alster, T.S.1    Williams, C.M.2
  • 16
    • 0034483686 scopus 로고    scopus 로고
    • Treatment of keloid scars with pulsed dye lasers and intralesional steroid.
    • Connell PG, Harland CC. Treatment of keloid scars with pulsed dye lasers and intralesional steroid. J Cutan Laser Ther 2000; 2:147-150
    • (2000) J Cutan Laser Ther , vol.2 , pp. 147
    • Connell, P.G.1    Harland, C.C.2
  • 17
    • 0036715319 scopus 로고    scopus 로고
    • Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments.
    • Manuskiatti W, Fitzpatrick RE. Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. Arch Dermatol 2002; 138:1149-1155
    • (2002) Arch Dermatol , vol.138 , pp. 1149
    • Manuskiatti, W.1    Fitzpatrick, R.E.2
  • 18
    • 85026155533 scopus 로고    scopus 로고
    • Berman B, Flores F. Interferons. In: Wolverton SE (ed). Comprehensive Dermatologic Drug Therapy. Philadelphia: WB Saunders, 2001:339-357
    • Berman B, Flores F. Interferons. In: Wolverton SE (ed). Comprehensive Dermatologic Drug Therapy. Philadelphia: WB Saunders, 2001:339-357
  • 19
    • 0024463303 scopus 로고
    • Short-term keloid treatment in vivo with human interferon alfa-2b results in a selective and persistent normalization of keloidal fibroblast collagen, glycosaminoglycan, and collagenase production in vitro.
    • Berman B, Duncan MR. Short-term keloid treatment in vivo with human interferon alfa-2b results in a selective and persistent normalization of keloidal fibroblast collagen, glycosaminoglycan, and collagenase production in vitro. J Am Acad Dermatol 1989; 21(Part 1):694-702
    • (1989) J Am Acad Dermatol , vol.21 , pp. 694
    • Berman, B.1    Duncan, M.R.2
  • 20
    • 0028358989 scopus 로고
    • Intralesional interferon alfa-2b has no effect in the treatment of keloids.
    • Wong TW, Chiu HC, Yip KM. Intralesional interferon alfa-2b has no effect in the treatment of keloids. Br J Dermatol 1994; 130:683-685
    • (1994) Br J Dermatol , vol.130 , pp. 683
    • Wong, T.W.1    Chiu, H.C.2    Yip, K.M.3
  • 21
    • 0030036864 scopus 로고    scopus 로고
    • Failure of interferon alpha-2b in the treatment of mature keloids.
    • Al-Khawajah MM. Failure of interferon alpha-2b in the treatment of mature keloids. Int J Dermatol 1996; 35:515-517
    • (1996) Int J Dermatol , vol.35 , pp. 515
    • Al-Khawajah, M.M.1
  • 22
    • 0030711701 scopus 로고    scopus 로고
    • Recurrence rates of excised keloids treated with postoperative triamcinolone, acetonide injections or interferon alfa-2b injections.
    • Berman B, Flores F. Recurrence rates of excised keloids treated with postoperative triamcinolone, acetonide injections or interferon alfa-2b injections. J Am Acad Dermatol 1997; 37:755-757
    • (1997) J Am Acad Dermatol , vol.37 , pp. 755
    • Berman, B.1    Flores, F.2
  • 23
    • 0031733642 scopus 로고    scopus 로고
    • Carbon dioxide laser ablation associated with interferon alfa-2b injections reduces the recurrence of keloids.
    • Conejo-Mir JS, Corbi R. Carbon dioxide laser ablation associated with interferon alfa-2b injections reduces the recurrence of keloids. J Am Acad Dermatol 1998; 39:1039-1040
    • (1998) J Am Acad Dermatol , vol.39 , pp. 1039
    • Conejo-Mir, J.S.1    Corbi, R.2
  • 24
    • 0025194152 scopus 로고
    • A controlled trial of intralesional recombinant interferon-gamma in the treatment of keloidal scarring. Clinical and histologic findings.
    • Granstein RD, Rook A, Flotte TJ, et al. A controlled trial of intralesional recombinant interferon-gamma in the treatment of keloidal scarring. Clinical and histologic findings. Arch Dermatol 1990; 126:1295-1302
    • (1990) Arch Dermatol , vol.126 , pp. 1295
    • Granstein, R.D.1    Rook, A.2    Flotte, T.J.3
  • 25
    • 0025086485 scopus 로고
    • Intralesional interferon gamma treatment of keloids and hypertrophic scars.
    • Larrabee Jr, WF, East CA, Jaffe HS, et al. Intralesional interferon gamma treatment of keloids and hypertrophic scars. Arch Otolaryngol Head Neck Surg 1990; 116:1159-1162
    • (1990) Arch Otolaryngol Head Neck Surg , vol.116 , pp. 1159
    • Larrabee, W.F.1    East, C.A.2    Jaffe, H.S.3
  • 26
    • 14644397395 scopus 로고    scopus 로고
    • New immune therapies for skin disease: imiquimod and related compounds.
    • Sauder D. New immune therapies for skin disease: imiquimod and related compounds. J Cutan Med Surg 2001; 5:2-6
    • (2001) J Cutan Med Surg , vol.5 , pp. 2
    • Sauder, D.1
  • 27
    • 0032619393 scopus 로고    scopus 로고
    • Imiquimod applied topically: a novel immune response modifier and new class of drug.
    • Miller RL, Gerster JF, Owens ML, et al. Imiquimod applied topically: a novel immune response modifier and new class of drug. Int J Immunopharmacol 1999; 21:1-14
    • (1999) Int J Immunopharmacol , vol.21 , pp. 1
    • Miller, R.L.1    Gerster, J.F.2    Owens, M.L.3
  • 28
    • 0141631880 scopus 로고    scopus 로고
    • Topical application of imiquimod 5% cream to excision sites is safe and effective in reducing keloid recurrences.
    • Kaufman J, Berman B. Topical application of imiquimod 5% cream to excision sites is safe and effective in reducing keloid recurrences. J Am Acad Dermatol 2002; 47(Suppl):S209-211
    • (2002) J Am Acad Dermatol , vol.47 , pp. S209
    • Kaufman, J.1    Berman, B.2
  • 29
    • 0036288305 scopus 로고    scopus 로고
    • Therapeutic response of a brother and sister with xeroderma pigmentosum to imiquimod 5% cream.
    • Weisberg NK, Varghese M. Therapeutic response of a brother and sister with xeroderma pigmentosum to imiquimod 5% cream. Dermatol Surg 2002; 28:518-523
    • (2002) Dermatol Surg , vol.28 , pp. 518
    • Weisberg, N.K.1    Varghese, M.2
  • 31
    • 3242730430 scopus 로고    scopus 로고
    • An open label safety study of topical imiquimod 5% cream in the treatment of molluscum contagiosum in children.
    • Barba AR, Kapoor S, Berman B. An open label safety study of topical imiquimod 5% cream in the treatment of molluscum contagiosum in children. Dermatol Online J 2001; 7:20
    • (2001) Dermatol Online J , vol.7 , pp. 20
    • Barba, A.R.1    Kapoor, S.2    Berman, B.3
  • 32
    • 0034754042 scopus 로고    scopus 로고
    • Are keloids really “gli-1oid”: high-level expression of gli-1 oncogene in keloids.
    • Kim A, Dicarlo J, Cohen C, et al. Are keloids really “gli-1oid”: high-level expression of gli-1 oncogene in keloids. J Am Acad Dermatol 2001; 45:707-711
    • (2001) J Am Acad Dermatol , vol.45 , pp. 707
    • Kim, A.1    Dicarlo, J.2    Cohen, C.3
  • 33
    • 0019435133 scopus 로고
    • Pharmacologic control of surface scarring in human beings.
    • Peacock Jr. EE, Pharmacologic control of surface scarring in human beings. Ann Surg 1981; 193:592-597
    • (1981) Ann Surg , vol.193 , pp. 592
    • Peacock, E.E.1
  • 34
    • 0030060205 scopus 로고    scopus 로고
    • Topical putrescine (Fibrostat) in treatment of hypertrophic scars: phase II study.
    • Dolynchuk KN, Ziesmann M, Serletti JM. Topical putrescine (Fibrostat) in treatment of hypertrophic scars: phase II study. Plast Reconstr Surg 1996; 97:117-123
    • (1996) Plast Reconstr Surg , vol.97 , pp. 117
    • Dolynchuk, K.N.1    Ziesmann, M.2    Serletti, J.M.3
  • 35
    • 0026485606 scopus 로고
    • The mechanism involved in the inhibitory action of tranilast, an anti-allergic drug, on the release of cytokines on PGE2 from human monocytes-macrophages.
    • Suzawa H, Kikuchi S, Arai N, et al. The mechanism involved in the inhibitory action of tranilast, an anti-allergic drug, on the release of cytokines on PGE2 from human monocytes-macrophages. Jpn J Pharmacol 1992; 60:85-90
    • (1992) Jpn J Pharmacol , vol.60 , pp. 85
    • Suzawa, H.1    Kikuchi, S.2    Arai, N.3
  • 36
    • 0022971857 scopus 로고
    • Retinoid effects on fibroblast proliferation and collagen synthesis in vitro and on fibrotic disease in vivo.
    • Daly TJ, Weston WL. Retinoid effects on fibroblast proliferation and collagen synthesis in vitro and on fibrotic disease in vivo. J Am Acad Dermatol 1986; 15(Part 2):900-902
    • (1986) J Am Acad Dermatol , vol.15 , pp. 900
    • Daly, T.J.1    Weston, W.L.2
  • 37
  • 38
  • 39
    • 0025039574 scopus 로고
    • Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphea skin in their production of collagen, glycosaminoglycans and fibronectin.
    • Berman B, Duncan MR. Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphea skin in their production of collagen, glycosaminoglycans and fibronectin. Br J Dermatol 1990; 123:339-346
    • (1990) Br J Dermatol , vol.123 , pp. 339
    • Berman, B.1    Duncan, M.R.2
  • 40
    • 0036172522 scopus 로고    scopus 로고
    • Prevention and treatment of keloids with intralesional verapamil.
    • D'Andrea F, Brongo S, Ferraro G, et al. Prevention and treatment of keloids with intralesional verapamil. Dermatology 2002; 204:60-62
    • (2002) Dermatology , vol.204 , pp. 60
    • D'Andrea, F.1    Brongo, S.2    Ferraro, G.3
  • 41
    • 0025243695 scopus 로고
    • Calcium antagonists retard extracellular matrix production in connective tissue equivalent.
    • Lee RC, Ping JA. Calcium antagonists retard extracellular matrix production in connective tissue equivalent. J Surg Res 1990; 49:463-466
    • (1990) J Surg Res , vol.49 , pp. 463
    • Lee, R.C.1    Ping, J.A.2
  • 42
    • 0035318908 scopus 로고    scopus 로고
    • Effect of tamoxifen on transforming growth factor beta 1 production by keloid and fetal fibroblasts.
    • Mikulec AA, Hanasono MM, Lum J, et al. Effect of tamoxifen on transforming growth factor beta 1 production by keloid and fetal fibroblasts. Arch Fac Plast Surg 2001; 3:111-114
    • (2001) Arch Fac Plast Surg , vol.3 , pp. 111
    • Mikulec, A.A.1    Hanasono, M.M.2    Lum, J.3
  • 43
    • 0032167774 scopus 로고    scopus 로고
    • Topical tamoxifen—a potential therapeutic regimen in treating excessive dermal scarring?
    • Hu D, Hughes MA, Cherry GW. Topical tamoxifen—a potential therapeutic regimen in treating excessive dermal scarring? Br J Plast Surg 1998; 51:462-469
    • (1998) Br J Plast Surg , vol.51 , pp. 462
    • Hu, D.1    Hughes, M.A.2    Cherry, G.W.3
  • 44
    • 0035142536 scopus 로고    scopus 로고
    • Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures.
    • Espana A, Solano T, Quintanilla E. Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures. Dermatol Surg 2001; 27:23-27
    • (2001) Dermatol Surg , vol.27 , pp. 23
    • Espana, A.1    Solano, T.2    Quintanilla, E.3
  • 45
    • 0034791601 scopus 로고    scopus 로고
    • The effects of a single dose of 5-fluorouracil on keloid scars: a clinical trial of timed wound irrigation after extralesional excision.
    • Uppal RS, Khan U, Kakar S, et al. The effects of a single dose of 5-fluorouracil on keloid scars: a clinical trial of timed wound irrigation after extralesional excision. Plast Reconstr Surg 2001; 108:1218-1224
    • (2001) Plast Reconstr Surg , vol.108 , pp. 1218
    • Uppal, R.S.1    Khan, U.2    Kakar, S.3
  • 46
    • 29244439598 scopus 로고    scopus 로고
    • Keloids: current concepts in pathogenesis and treatment.
    • Craft N. Keloids: current concepts in pathogenesis and treatment. Cosmet Dermatol 2002; 15:35-39
    • (2002) Cosmet Dermatol , vol.15 , pp. 35
    • Craft, N.1
  • 47
    • 0036312318 scopus 로고    scopus 로고
    • International clinical recommendations on scar management.
    • Mustoe TA, Cooter RD, Gold MH, et al. International clinical recommendations on scar management. Plast Reconstr Surg 2002; 110:560-571
    • (2002) Plast Reconstr Surg , vol.110 , pp. 560
    • Mustoe, T.A.1    Cooter, R.D.2    Gold, M.H.3


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