Patched is a dependence receptor;Patched est un « récepteur à dépendance »

Medecine/Sciences

Volumn 19, Issue 11, 2003, Pages 1062-

  Mehlen, Patrick ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; LIGAND; MEMBRANE PROTEIN; PATCHED RECEPTORS;

APOPTOSIS; CELL SURVIVAL; EMBRYONIC STRUCTURES; NEUROEPITHELIUM; NONHUMAN; NOTE; PROTEIN DEGRADATION; ARTICLE; HUMAN; PHYSIOLOGY;

ERINACEIDAE;

APOPTOSIS; HUMANS; LIGANDS; MEMBRANE PROTEINS; RECEPTORS, CELL SURFACE;

EID: 0642272513     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/200319111062     Document Type: Note

References (3)

1. Mehlen P, Rabizadeh S, Snipas SJ, Assa-Munt N, Salvesen GS, Bredesen DE. The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis. Nature 1998; 395: 801-4.
2. Thibert C, Teillet MA, Lapointe F, Mazelin L, Le Douarin NM, Mehlen P. Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog. Science 2003; 301: 843-6.
3. Charrier JB, Teillet MA, Lapointe F, Le Douarin NM. Defining subregions of Hensen's node essential for caudalward movement, midline development and cell survival. Development 1999; 126: 4771-83.