In vitro effects of combinations of antipseudomonal agents against seven strains of multidrug-resistant Pseudomonas aeruginosa

Journal of Antimicrobial Chemotherapy

Volumn 52, Issue 6, 2003, Pages 911-914

  Oie, Shigeharu ^a   Uematsu, Toshinari ^a   Sawa, Akihiro ^a   Mizuno, Hidekazu ^a   Tomita, Masaaki ^b   Ishida, Shiro ^c   Okano, Yoshiro ^c   Kamiya, Akira ^a  

^a YAMAGUCHI UNIVERSITY HOSPITAL   (Japan)

^b Yamaguchi Prefectural Research Institute of Public Health   (Japan)

^c TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Amikacin; Antimicrobial agents; Aztreonam; Ceftazidime; Combined effects; P.aeruginosa

Indexed keywords

AGAR; AMIKACIN; ANTIBIOTIC AGENT; AZTREONAM; CEFTAZIDIME; CIPROFLOXACIN; MEROPENEM; PIPERACILLIN; SULPERAZON;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; BACTERIUM ISOLATE; CONTROLLED STUDY; DILUTION; DNA EXTRACTION; DNA RESTRICTION; DRUG EFFICACY; DRUG POTENTIATION; GEOGRAPHIC DISTRIBUTION; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PSEUDOMONAS AERUGINOSA; PULSED FIELD GEL ELECTROPHORESIS; STRAIN IDENTIFICATION;

ANTI-BACTERIAL AGENTS; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DRUG INTERACTIONS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG THERAPY, COMBINATION; ELECTROPHORESIS, GEL, PULSED-FIELD; HUMANS; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 0348149156     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg478     Document Type: Article

References (21)

1. Chen, H. Y., Yuan, M., Ibrahim-Elmagboul, I. B. et al. (1995). National survey of susceptibility to antimicrobials amongst clinical isolates of Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 35, 521-34.
2. Sofianou, D., Tsakris, A., Skoura, L. et al. (1997). Extended high-level cross-resistance to antipseudomonal antibiotics amongst Pseudomonas aeruginosa isolates in a university hospital. Journal of Antimicrobial Chemotherapy 40, 740-2.
3. Bonfiglio, G., Carciotto, V., Russo, G. et al. (1998). Antibiotic resistance in Pseudomonas aeruginosa: an Italian survey. Journal of Antimicrobial Chemotherapy 41, 307-10.
4. Mayer, I. & Nagy, E. (1999). Investigation of the synergic effects of aminoglycoside-fluoroquinolone and third-generation cephalosporin combinations against clinical isolates of Pseudomonas spp. Journal of Antimicrobial Chemotherapy 43, 651-7.
5. Oie, S., Sawa, A., Kamiya, A. et al. (1999). In-vitro effects of a combination of antipseudomonal antibiotics against multi-drug resistant Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 44, 689-91.
6. Giamarellos-Bourboulis, E. J., Grecka, P. & Giamarellou, H. (1997). Comparative in vitro interactions of ceftazidime, meropenem, and imipenem with amikacin on multiresistant Pseudomonas aeruginosa. Diagnostic Microbiology and Infectious Disease 29, 81-6.
7. Giamarellos-Bourboulis, E. J., Grecka, P. & Giamarellou, H. (1996). In-vitro interactions of DX-8739, a new carbapenem, meropenem and imipenem with amikacin against multiresistant Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 38, 287-91.
8. Roussel-Delvallez, M., Wallet, F., Delpierre, F. et al. (1996). In vitro bactericidal effect of a β-lactam + aminoglycoside combination against multiresistant Pseudomonas aeruginosa and Acinetobacter baumannii. Journal of Chemotherapy 8, 365-8.
9. Weiss, K. & Lapointe, J. R. (1995). Routine susceptibility testing of four antibiotic combinations for improvement of laboratory guide to therapy of cystic fibrosis infections caused by Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy 39, 2411-4.
10. Gerceker, A. A. & Gurler, B. (1995). In-vitro activities of various antibiotics, alone and in combination with amikacin against Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 36, 707-11.
11. Cappelletty, D. M., Kang, S. L., Palmer, S. M. et al. (1995). Pharmacodynamics of ceftazidime administered as continuous infusion or intermittent bolus alone and in combination with single daily-dose amikacin against Pseudomonas aeruginosa in an in vitro infection model. Antimicrobial Agents and Chemotherapy 33, 1797-801.
12. Jenkins, S. G. & Lewis, J. W. (1995). Synergistic interaction between ofloxacin and cefotaxime against common clinical pathogens. Infection 23, 154-62.
13. Fujita, J., Negayama, K., Takigawa, K. et al. (1992). Activity of antibiotics against resistant Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 29, 539-46.
14. Rolston, K. V. I. & Bodey, G. P. (1992). Pseudomonas aeruginosa infection in cancer patients. Cancer Investigation 10, 43-59.
15. Hallander, H. O., Dornbusch, K., Gezelius, L. et al. (1982). Synergism between aminoglycosides and cephalosporins with anti-pseudomonal activity: interaction index and killing curve method. Antimicrobial Agents and Chemotherapy 22, 743-52.
16. Cavallo, J. D., Plesiat, P., Couetdic, G. et al. (2002). Mechanisms of β-lactam resistance in Pseudomonas aeruginosa: prevalence of OprM-overproducing strains in a French multicentre study (1997). Journal of Antimicrobial Chemotherapy 50, 1039-43.
17. Ziha-Zarifi, I., Llanes, C., Köhler, T. et al. (1999). In vivo emergence of multidrug-resistant mutants of Pseudomonas aeruginosa overexpressing the active efflux system MexA-MexB-OprM. Antimicrobial Agents and Chemotherapy 43, 287-91.
18. Schweizer, H. P. (2003). Efflux as a mechanism of resistance to antimicrobials in Pseudomonas aeruginosa and related bacteria: unanswered questions. Genetics and Molecular Research 2, 48-62.
19. Murray, B. E., Singh, K. V., Markowitz, S. M. et al. (1991). Evidence for clonal spread of a single strain of β-lactamase-producing Enterococcus (Streptococcus) faecalis to six hospitals in five states. Journal of Infectious Diseases 163, 780-5.
20. National Committee for Clinical Laboratory Standards. (1990). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically - Second Edition: Approved Standard M7-A2. NCCLS, Villanova, PA, USA.
21. Rochon-Edouard, S., Pestel-Caron, M., Lemeland, J.-F. et al. (2000). In vitro synergic effects of double and triple combinations of β-lactams, vancomycin, and netilmicin against methicillin-resistant Staphylococcus aureus strains. Antimicrobial Agents and Chemotherapy 44, 3055-60.