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Volumn 43, Issue 2, 1999, Pages 287-291

In vivo emergence of multidrug-resistant mutants of Pseudomonas aeruginosa overexpressing the active efflux system mexA-mexB-OprM

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; QUINOLINE DERIVATIVE; TETRACYCLINE DERIVATIVE; TRIMETHOPRIM;

EID: 0033039934     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.2.287     Document Type: Article
Times cited : (244)

References (40)
  • 3
    • 0028789107 scopus 로고
    • Mechanisms of resistance to beta-lactam antibiotics amongst Pseudomonas aeruginosa isolates collected in the UK in 1993
    • Chen, H. Y., M. Yuan, and D. M. Livermore. 1995. Mechanisms of resistance to beta-lactam antibiotics amongst Pseudomonas aeruginosa isolates collected in the UK in 1993. J. Med. Microbiol. 43:300-309.
    • (1995) J. Med. Microbiol. , vol.43 , pp. 300-309
    • Chen, H.Y.1    Yuan, M.2    Livermore, D.M.3
  • 4
    • 0000527903 scopus 로고
    • Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans
    • Figurski, D. H., and D. R. Helinski. 1979. Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. Proc. Natl. Acad. Sci. USA 76:1648-1652.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 1648-1652
    • Figurski, D.H.1    Helinski, D.R.2
  • 5
    • 0029057714 scopus 로고
    • Development of resistance during antimicrobial therapy: A review of antibiotic classes and patient characteristics in 173 studies
    • Fish, D. N., S. C. Piscitelli, and L. H. Danziger. 1995. Development of resistance during antimicrobial therapy: a review of antibiotic classes and patient characteristics in 173 studies. Pharmacotherapy 15:279-291.
    • (1995) Pharmacotherapy , vol.15 , pp. 279-291
    • Fish, D.N.1    Piscitelli, S.C.2    Danziger, L.H.3
  • 7
    • 0027467503 scopus 로고
    • Persistence of Pseudomonas aeruginosa strains in seven cystic fibrosis patients followed over 20 months
    • Godard, C., P. Plésiat, and Y. Michel-Briand. 1993. Persistence of Pseudomonas aeruginosa strains in seven cystic fibrosis patients followed over 20 months. Eur. J. Med. 2:117-120.
    • (1993) Eur. J. Med. , vol.2 , pp. 117-120
    • Godard, C.1    Plésiat, P.2    Michel-Briand, Y.3
  • 8
    • 0027978598 scopus 로고
    • Isolation of OprM-deficient mutants of Pseudomonas aeruginosa by transposon insertion mutagenesis: Evidence of involvement in multiple antibiotic resistance
    • Gotoh, N., N. Itoh, H. Tsujimoto, J. Yamagishi, Y. Oyamada, and T. Nishino. 1994. Isolation of OprM-deficient mutants of Pseudomonas aeruginosa by transposon insertion mutagenesis: evidence of involvement in multiple antibiotic resistance. FEMS Microbiol. Lett. 122:267-273.
    • (1994) FEMS Microbiol. Lett. , vol.122 , pp. 267-273
    • Gotoh, N.1    Itoh, N.2    Tsujimoto, H.3    Yamagishi, J.4    Oyamada, Y.5    Nishino, T.6
  • 9
    • 0020536197 scopus 로고
    • Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels
    • Hitchcock, P. J., and T. M. Brown. 1983. Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels. J. Bacteriol. 154:269-277.
    • (1983) J. Bacteriol. , vol.154 , pp. 269-277
    • Hitchcock, P.J.1    Brown, T.M.2
  • 10
    • 0026490125 scopus 로고
    • Occurrence of the nfxB type mutations in clinical isolates of Pseudomonas aeruginosa
    • Jakics, E. B., S. Iyobe, K. Hirai, H. Fukuda, and H. Hashimoto. 1992. Occurrence of the nfxB type mutations in clinical isolates of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 36:2562-2565.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 2562-2565
    • Jakics, E.B.1    Iyobe, S.2    Hirai, K.3    Fukuda, H.4    Hashimoto, H.5
  • 11
    • 26544449769 scopus 로고    scopus 로고
    • Unpublished data
    • Köhler, T. Unpublished data.
    • Köhler, T.1
  • 13
    • 0031016991 scopus 로고    scopus 로고
    • Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa
    • Köhler, T., M. Michéa Hamzehpour, U. Henze, N. Gotoh, L. Kocjancic Curty, and J. C. Pechère. 1997. Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa. Mol. Microbiol. 23:345-354.
    • (1997) Mol. Microbiol. , vol.23 , pp. 345-354
    • Köhler, T.1    Michéa Hamzehpour, M.2    Henze, U.3    Gotoh, N.4    Curty, L.K.5    Pechère, J.C.6
  • 15
    • 0028067837 scopus 로고
    • Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: Resistance to tetracycline, chloramphenicol, and norfloxacin
    • Li, X. Z., D. M. Livermore, and H. Nikaido. 1994. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin. Antimicrob. Agents Chemother. 38:1732-1741.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1732-1741
    • Li, X.Z.1    Livermore, D.M.2    Nikaido, H.3
  • 16
    • 0028050605 scopus 로고
    • Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: Active efflux as a contributing factor to beta-lactam resistance
    • Li, X. Z., D. Ma, D. M. Livermore, and H. Nikaido. 1994. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to beta-lactam resistance. Antimicrob. Agents Chemother. 38:1742-1752.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1742-1752
    • Li, X.Z.1    Ma, D.2    Livermore, D.M.3    Nikaido, H.4
  • 17
    • 0029129966 scopus 로고
    • Role of MexA-MexB-OprM in antibiotic efflux in Pseudomonas aeruginosa
    • Li, X. Z., H. Nikaido, and K. Poole. 1995. Role of MexA-MexB-OprM in antibiotic efflux in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:1948-1953.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 1948-1953
    • Li, X.Z.1    Nikaido, H.2    Poole, K.3
  • 18
    • 0031952858 scopus 로고    scopus 로고
    • β-Lactamase inhibitors are substrates for the multidrug efflux pumps of Pseudomonas aeruginosa
    • Li, X. Z., R. Srikumar, and K. Poole. 1998. β-Lactamase inhibitors are substrates for the multidrug efflux pumps of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 42:399-403.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 399-403
    • Li, X.Z.1    Srikumar, R.2    Poole, K.3
  • 19
    • 0021178894 scopus 로고
    • Penicillin-binding proteins, porins and outer-membrane permeability of carbenicillin-resistant and -susceptible strains of Pseudomonas aeruginosa
    • Livermore, D. M. 1984. Penicillin-binding proteins, porins and outer-membrane permeability of carbenicillin-resistant and -susceptible strains of Pseudomonas aeruginosa. J. Med. Microbiol. 18:261-270.
    • (1984) J. Med. Microbiol. , vol.18 , pp. 261-270
    • Livermore, D.M.1
  • 20
    • 0026722581 scopus 로고
    • Cross-resistance to meropenem. Cephems, and quinolones in Pseudomonas aeruginosa
    • Masuda, N., and S. Ohya. 1992. Cross-resistance to meropenem. cephems, and quinolones in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 36:1847-1851.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 1847-1851
    • Masuda, N.1    Ohya, S.2
  • 21
    • 0028927372 scopus 로고
    • Outer membrane proteins responsible for multiple drug resistance in Pseudomonas aeruginosa
    • Masuda, N., E. Sakagawa, and S. Ohya. 1995. Outer membrane proteins responsible for multiple drug resistance in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:645-649.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 645-649
    • Masuda, N.1    Sakagawa, E.2    Ohya, S.3
  • 22
    • 0016694617 scopus 로고
    • The use of analytical isoelectric focusing for detection and identification of β-lactamases
    • Matthew, M., A. M. Harris, M. J. Marshall, and G. W. Ross. 1975. The use of analytical isoelectric focusing for detection and identification of β-lactamases. J. Gen. Microbiol. 88:169-175.
    • (1975) J. Gen. Microbiol. , vol.88 , pp. 169-175
    • Matthew, M.1    Harris, A.M.2    Marshall, M.J.3    Ross, G.W.4
  • 23
    • 0028828456 scopus 로고
    • OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa
    • Michéa Hamzehpour, M., J. C. Pechère, P. Plésiat, and T. Köhler. 1995. OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:2392-2396.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2392-2396
    • Michéa Hamzehpour, M.1    Pechère, J.C.2    Plésiat, P.3    Köhler, T.4
  • 24
    • 0026019764 scopus 로고
    • A series of wide-host-range low-copy-number vectors that allow direct screening for recombinants
    • Morales, V. M., A. Bäckman, and M. Bagdasarian. 1991. A series of wide-host-range low-copy-number vectors that allow direct screening for recombinants. Gene 97:39-47.
    • (1991) Gene , vol.97 , pp. 39-47
    • Morales, V.M.1    Bäckman, A.2    Bagdasarian, M.3
  • 25
    • 0029845913 scopus 로고    scopus 로고
    • Muitidrug efflux pumps of gram-negative bacteria
    • Nikaido, H. 1996. Muitidrug efflux pumps of gram-negative bacteria. J. Bacteriol. 178:5853-5859.
    • (1996) J. Bacteriol. , vol.178 , pp. 5853-5859
    • Nikaido, H.1
  • 26
    • 0027494050 scopus 로고
    • Multiple antibiotic resistance in Pseudomonas aeruginosa: Evidence for involvement of an efflux operon
    • Poole, K., K. Krebes, C. Mcnally, and S. Neshat. 1993. Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon. J. Bacteriol. 175:7363-7372.
    • (1993) J. Bacteriol. , vol.175 , pp. 7363-7372
    • Poole, K.1    Krebes, K.2    McNally, C.3    Neshat, S.4
  • 27
    • 0029815432 scopus 로고    scopus 로고
    • Expression of the muitidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression
    • Poole, K., K. Tetro, Q. X. Zhao, S. Neshat, D. E. Heinrichs, and N. Bianco. 1996. Expression of the muitidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression. Antimicrob. Agents Chemother. 40:2021-2028.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2021-2028
    • Poole, K.1    Tetro, K.2    Zhao, Q.X.3    Neshat, S.4    Heinrichs, D.E.5    Bianco, N.6
  • 28
    • 0020456610 scopus 로고
    • Emergence of resistance to β-lactam and aminoglycoside antibiotics during moxalactam therapy of Pseudomonas aeruginosa infection
    • Preheim, L. C., R. G. Penn, C. C. Sanders, R. V. Goering, and D. K. Giger. 1982. Emergence of resistance to β-lactam and aminoglycoside antibiotics during moxalactam therapy of Pseudomonas aeruginosa infection. Antimicrob. Agents Chemother. 22:1037-1041.
    • (1982) Antimicrob. Agents Chemother. , vol.22 , pp. 1037-1041
    • Preheim, L.C.1    Penn, R.G.2    Sanders, C.C.3    Goering, R.V.4    Giger, D.K.5
  • 29
    • 0020327589 scopus 로고
    • Resistance of Pseudomonas aeruginosa PAO to nalidixic acid and low levels of β-lactam antibiotics: Mapping of chromosomal genes
    • Rella, M., and D. Haas. 1982. Resistance of Pseudomonas aeruginosa PAO to nalidixic acid and low levels of β-lactam antibiotics: mapping of chromosomal genes. Antimicrob. Agents Chemother. 22:242-249.
    • (1982) Antimicrob. Agents Chemother. , vol.22 , pp. 242-249
    • Rella, M.1    Haas, D.2
  • 30
    • 0025047140 scopus 로고
    • Broad-host-range gyrase A gene probe
    • Robillard, N. J. 1990. Broad-host-range gyrase A gene probe. Antimicrob. Agents Chemother. 34:1889-1894.
    • (1990) Antimicrob. Agents Chemother. , vol.34 , pp. 1889-1894
    • Robillard, N.J.1
  • 31
    • 0023835049 scopus 로고
    • Genetic and physiological characterization of ciprofloxacin resistance in Pseudomonas aeruginosa PAO
    • Robillard, N. J., and A. L. Scarpa. 1988. Genetic and physiological characterization of ciprofloxacin resistance in Pseudomonas aeruginosa PAO. Antimicrob. Agents Chemother. 32:535-539.
    • (1988) Antimicrob. Agents Chemother. , vol.32 , pp. 535-539
    • Robillard, N.J.1    Scarpa, A.L.2
  • 32
    • 0020788109 scopus 로고
    • Emergence of resistance during therapy with the newer β-lactam antibiotics: Role of the inducible β-lactamases and implications for the future
    • Sanders, C. C., and W. E. Sanders, Jr. 1983. Emergence of resistance during therapy with the newer β-lactam antibiotics: role of the inducible β-lactamases and implications for the future. Rev. Infect. Dis. 5:639-648.
    • (1983) Rev. Infect. Dis. , vol.5 , pp. 639-648
    • Sanders, C.C.1    Sanders W.E., Jr.2
  • 33
    • 0020055487 scopus 로고
    • Development of resistance to beta-lactam antibiotics during therapy of Pseudomonas aeruginosa infections
    • Shannon, K., A. King, and I. Phillips. 1982. Development of resistance to beta-lactam antibiotics during therapy of Pseudomonas aeruginosa infections. Lancet i:1466.
    • (1982) Lancet , vol.1 , pp. 1466
    • Shannon, K.1    King, A.2    Phillips, I.3
  • 34
    • 0002988279 scopus 로고    scopus 로고
    • Definition and determination of in vitro antibiotic susceptibility breakpoints for bacteria. Technical recommendations for in vitro susceptibility testing
    • Sirot, J., P. Courvalin, and C. J. Soussy. 1996. Definition and determination of in vitro antibiotic susceptibility breakpoints for bacteria. Technical recommendations for in vitro susceptibility testing. Clin. Microbiol. Infect. 2:S5-S25.
    • (1996) Clin. Microbiol. Infect. , vol.2
    • Sirot, J.1    Courvalin, P.2    Soussy, C.J.3
  • 35
    • 0024787898 scopus 로고
    • Transformation of Pseudomonas aeruginosa by electroporation
    • Smith, A. W., and B. H. Iglewski. 1989. Transformation of Pseudomonas aeruginosa by electroporation. Nucleic Acids Res. 17:10509.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 10509
    • Smith, A.W.1    Iglewski, B.H.2
  • 36
    • 0029655920 scopus 로고    scopus 로고
    • Meropenem resistance in Pseudomonas aeruginosa
    • Basel
    • Sumita, Y., and M. Fukasawa. 1996. Meropenem resistance in Pseudomonas aeruginosa. Chemotherapy (Basel) 42:47-56.
    • (1996) Chemotherapy , vol.42 , pp. 47-56
    • Sumita, Y.1    Fukasawa, M.2
  • 37
    • 0029134774 scopus 로고
    • Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: Criteria for bacterial strain typing
    • Tenover, F. C., R. D, Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
    • (1995) J. Clin. Microbiol. , vol.33 , pp. 2233-2239
    • Tenover, F.C.1    Arbeit, R.D.2    Goering, R.V.3    Mickelsen, P.A.4    Murray, B.E.5    Persing, D.H.6    Swaminathan, B.7
  • 38
    • 0020055346 scopus 로고
    • A sensitive silver staining method for detecting lipopolysaccharides in polyacrylamide gels
    • Tsai, C. M., and C. E. Frash. 1982. A sensitive silver staining method for detecting lipopolysaccharides in polyacrylamide gels. Anal. Biochem. 119: 115-119.
    • (1982) Anal. Biochem. , vol.119 , pp. 115-119
    • Tsai, C.M.1    Frash, C.E.2
  • 40
    • 0028303739 scopus 로고
    • Mechanisms of high-level resistance to quinolones in urinary tract isolates of Pseudomonas aeruginosa
    • Yoshida, T., T. Muratani, S. Iyobe, and S. Mitsuhashi. 1994. Mechanisms of high-level resistance to quinolones in urinary tract isolates of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 38:1466-1469.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1466-1469
    • Yoshida, T.1    Muratani, T.2    Iyobe, S.3    Mitsuhashi, S.4


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