Anemia and red cell transfusion in critically ill patients

Critical Care Medicine

Volumn 31, Issue 12 SUPPL., 2003, Pages

  Hébert, Paul C ^a,c,d   Tinmouth, Alan ^a   Corwin, Howard ^b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^c ONTARIO MINISTRY OF HEALTH AND LONG TERM CARE   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Alternatives to transfusion; Anemia; Critical illness; Erythropoietin; Transfusion

Indexed keywords

ACETYLSALICYLIC ACID; ERYTHROPOIETIN; HEMOGLOBIN; NONSTEROID ANTIINFLAMMATORY AGENT; RECOMBINANT ERYTHROPOIETIN;

ANEMIA; BLEEDING; CLINICAL TRIAL; CRITICAL ILLNESS; ERYTHROCYTE TRANSFUSION; ERYTHROPOIESIS; HEMOGLOBIN DETERMINATION; HIGH RISK POPULATION; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; TREATMENT INDICATION;

EID: 0348147559     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ccm.0000117291.73810.5a     Document Type: Review

References (50)

1. Liano F, Garcia-Martin F, Gallego A, et al: Easy and early prognosis in acute tubular necrosis: A forward analysis of 228 cases. Nephron 1989; 51:307-313
2. Vincent JL, Baron J-F, Reinhart K, et al: Anemia and blood transfusion in critically ill patients. JAMA 2002; 288:1499-1507
3. Wilkerson DK, Rosen AL, Sehgal LR, et al: Limits of cardiac compensation in anemic baboons. Surgery 1988; 103:665-670
4. Leung JM, Weiskopf RB, Feiner J, et al: Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans. Anesthesiology 2000; 93: 1004-1010
5. Expert Working Group: Guidelines for red blood cell and plasma transfusion for adults and children: Report of the expert working group. Can Med Assoc J 1997; 156(Suppl 11):S1-S24
6. Bayer WL, Coenen WM, Jenkins DC, et al: The use of blood and blood components in 1,769 patients undergoing open-heart surgery. Ann Thorac Surg 1980; 29:117-122
7. Gollub S, Bailey CP: Management of major surgical blood loss without transfusion. JAMA 1966; 198:149-152
8. Carson JL, Spence RK, Poses RM, et al: Severity of anaemia and operative mortality and morbidity. Lancet 1988; 1:727-729
9. Spence RK, Carson JA, Poses R, et al: Elective surgery without transfusion: Influence of preoperative hemoglobin level and blood loss on mortality. Am J Surg 1990; 159:320-324
10. Fullerton WT, Turner AG: Exchange transfusion in treatment of severe anaemia in pregnancy. Lancet 1962; 282:75-78
11. Kawaguchi A, Bergsland J, Subramanian S: Total bloodless open heart surgery in the pediatric age group. Circulation 1984; 70: 1-30
12. Nelson AH, Fleisher LA, Rosenbaum SH: Relationship between postoperative anemia and cardiac morbidity in high-risk vascular patients in the intensive care unit. Crit Care Med 1993; 21:860-866
13. Lunn JN, Elwood PC: Anaemia and surgery. BMJ 1970; 3:71-73
14. Gopalrao T: Should anemia stop surgery? Int Surg 1971; 55:250-255
15. Ott DA, Cooley DA: Cardiovascular surgery in Jehovah's Witnesses: Report of 542 operations without blood transfusion. JAMA 1977; 238:1256-1258
16. Graves CL, Allen RM: Anesthesia in the presence of severe anemia. Rocky Mt Med J 1974; 67:35-40
17. Simmons CW Jr, Messmer BJ, Hallman GL, et al: Vascular surgery in Jehovah's Witnesses. JAMA 1970; 213:1032-1034
18. Viele MK, Weiskopf RB: What can we learn about the need for transfusion from patients who refuse blood? The experience with Jehovah's Witnesses. Transfusion 1994; 34: 396-401
19. Slawson KB: Anaesthesia for the patient in renal failure. Br J Anaesth 1972; 44:277-282
20. Aldrete JA, Daniel W, O'Higghins JW, et al: Analysis of anesthetic-related morbidity in human recipients of renal holografts. Anesth Analg 1971; 50:321-329
21. Samuel JR, Powell D: Renal transplantation: Anesthetic experience of 100 cases. Anaesthesia 1970; 25:165-176
22. Alexiu O, Mircea N, Balaban M, et al: Gastro-intestinal haemorrhage from peptic ulcer: An evaluation of bloodless transfusion and early surgery. Anaesthesia 1975; 30:609-615
23. Audet A-M, Goodnough LT: Practice strategies for elective red blood cell transfusion. Ann Intern Med 1992; 116:403-406
24. American Society of Anesthesiologists Task Force on Blood Component Therapy: Practice guidelines for blood component therapy. Anesthesiology 1996; 84:732-747
25. Consensus Conference (National Institutes of Health): Perioperative red blood cell transfusion. JAMA 1988; 260:2700-2703
26. Welch HG, Meehan KR, Goodnough LT: Prudent strategies for elective red blood cell transfusion. Ann Intern Med 1992; 116:393-402
27. Cane RD: Hemoglobin: How much is enough? Crit Care Med 1990; 18:1046-1047
28. Crosby ET: Perioperative haemotherapy: I. Indications for blood component transfusion. Can J Anesth 1992; 39:695-707
29. Carson JL, Duff A, Poses RM, et al: Effects of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet 1996; 348:1055-1060
30. Hebert PC, Wells G, Tweeddale M, et al: Does transfusion practice affect mortality in critically ill patients? Am J Respir Crit Care Med 1997; 155:1618-1623
31. Wu WC, Rathore SS, Wang Y, et al: Blood transfusion in elderly patient's with acute myocardial infarction. N Engl J Med 2001; 345:1230-1236
32. Carson JL, Duff A, Berlin JA, et al: Perioperative blood transfusion and postoperative mortality. JAMA 1998; 279:199-205
33. Vincent JL, Baron J-F, Reinhart K, et al: Anemia and blood transfusion in critically ill patients. JAMA 2002; 288:1499-1507
34. Hebert PC, Fergusson DA: Red blood cell transfusions in critically ill patients. JAMA 2002; 288:1525-1526
35. Carson JL, Hill S, Carless P, et al: Transfusion triggers: A systematic review of the literature. Trans Med Rev 2002; 16:187-199
36. Hebert PC, Wells G, Blajchman MA, et al: A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999; 340:409-417
37. Hebert PC, Yetisir E, Martin C, et al: Is a low transfusion threshold safe in critically ill patients with cardiovascular disease? Crit Care Med 2001; 29:227-234
38. Bordin JO, Heddle NM, Blajchman MA: Biologic effects of leukocytes present in transfused cellular blood products. Blood 1994; 84:1703-1721
39. van de Watering LM, Hermans J, Houbiers JG, et al: Beneficial effects of leukocyte depletion of transfused blood on postoperative complications in patients undergoing cardiac surgery: A randomized clinical trial. Circulation 1998; 97:562-568
40. Rivers E, Nguyen B, Havstad MA, et al: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-1377
41. Rodriguez RM, Corwin HL, Gettinger A, et al: Nutritional deficiencies and blunted erythropoietin response as causes of the anemia of critical illness. J Crit Care 2001; 16:36-41
42. Frede S, Fandrey J, Pagel H, et al: Erythropoietin gene expression is suppressed after lipopolysaccharide or interleukin-1 beta injections in rats. Am J Physiol 1997; 273:t-71
43. Jelkmann W: Proinflammatory cytokines lowering erythropoietin production. J Interferon Res 1998; 18:555-559
44. Means RT Jr, Krantz SB: Progress in understanding the pathogenesis of the anemia of chronic disease. Blood 1992; 80:1639-1647
45. Krantz SB: Pathogenesis and treatment of the anemia of chronic disease. Am J Med Sci 1994; 307:353-359
46. Gabriel A, Kozek S, Chiari A, et al: High-dose recombinant human erythropoietin stimulates reticulocyte production in patients with multiple organ dysfunction syndrome. J Trauma 1998; 44:361-367
47. Corwin HL, Gettinger A, Rodriguez RM, et al: Efficacy of recombinant human erythropoietin in the critically ill patient: A randomized, double-blind, placebo-controlled trial. Crit Care Med 1999; 27:2346-2350
48. Corwin HL, Gettinger A, Pearl RG, et al: Efficacy of recombinant human erythropoietin in critically ill patients: A randomized controlled trial. JAMA 2002; 288: 2827-2835
49. Silver MJ, Bazzan A, Corwin H, et al: A randomized double blind placebo controlled trial of recombinant human erythropoietin in long term acute care patients. Crit Care Med 2003; 31(Suppl):A167
50. Corwin HL, Krantz SB: Anemia of the critically ill: 'Acute' anemia of chronic disease. Crit Care Med 2000; 28:3098-3099