메뉴 건너뛰기




Volumn 134, Issue 5, 2003, Pages 827-834

The immunophenotype and activation status of the lymphocytic infiltrate in human breast cancers, the role of the major histocompatibility complex in cell-mediated immune mechanisms, and their association with prognostic indicators

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; ESTROGEN RECEPTOR; HLA DR ANTIGEN; INTERLEUKIN 2 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 0348134670     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(03)00292-7     Document Type: Article
Times cited : (61)

References (38)
  • 1
    • 0021943245 scopus 로고
    • Human tumor-infiltrating lymphocytes: A marker of host response
    • Vose BM, Moore M. Human tumor-infiltrating lymphocytes: a marker of host response [Review]. Sem Hemat 1985;22: 27-40.
    • (1985) Sem Hemat , vol.22 , pp. 27-40
    • Vose, B.M.1    Moore, M.2
  • 2
    • 0024237293 scopus 로고
    • Same peculiar subset of HML1+ lymphocytes present within normal intestinal epithelium is associated with tumoral epithelium of gastrointestinal carcinomas
    • Jarry A, Cerf-Bensussan N, Brousse N, Guy-Grand D, Muzeau F, Potet F. Same peculiar subset of HML1+ lymphocytes present within normal intestinal epithelium is associated with tumoral epithelium of gastrointestinal carcinomas. Gut 1988;29:1632-8.
    • (1988) Gut , vol.29 , pp. 1632-1638
    • Jarry, A.1    Cerf-Bensussan, N.2    Brousse, N.3    Guy-Grand, D.4    Muzeau, F.5    Potet, F.6
  • 3
    • 0027324601 scopus 로고
    • Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells
    • Cepek KL, Parker CM, Madara JL, Brenner MB. Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J Immun 1993;150:3459-70.
    • (1993) J Immun , vol.150 , pp. 3459-3470
    • Cepek, K.L.1    Parker, C.M.2    Madara, J.L.3    Brenner, M.B.4
  • 4
    • 0019230964 scopus 로고
    • T-cell growth factor
    • Smith KA. T-cell growth factor [Review]. Immun Rev 1980; 51:337-57.
    • (1980) Immun Rev , vol.51 , pp. 337-357
    • Smith, K.A.1
  • 5
    • 0022536230 scopus 로고
    • The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes
    • Waldmann TA. The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes. Science 1986;232:727-32.
    • (1986) Science , vol.232 , pp. 727-732
    • Waldmann, T.A.1
  • 6
    • 0025778240 scopus 로고
    • The interleukin-2 receptor
    • Waldmann TA. The interleukin-2 receptor [Review]. J Biol Chem 1991;266:2681-4.
    • (1991) J Biol Chem , vol.266 , pp. 2681-2684
    • Waldmann, T.A.1
  • 7
    • 0025775935 scopus 로고
    • Lymphokines and the immune response: The central role of interleukin-2
    • Swain SL. Lymphokines and the immune response: the central role of interleukin-2 [Review]. Curr Op Immun 1991;3:304-10.
    • (1991) Curr Op Immun , vol.3 , pp. 304-310
    • Swain, S.L.1
  • 8
    • 0020563815 scopus 로고
    • Immunohistologic characterization of major histocompatibility antigens and inflammatory cellular infiltrate in human breast cancer
    • Bhan AK, DesMarais CL. Immunohistologic characterization of major histocompatibility antigens and inflammatory cellular infiltrate in human breast cancer. J Natl Canc Inst 1983;71:507-16.
    • (1983) J Natl Canc Inst , vol.71 , pp. 507-516
    • Bhan, A.K.1    DesMarais, C.L.2
  • 9
    • 0021346981 scopus 로고
    • Characterization of breast cancer infiltrates using monoclonal antibodies to human leukocyte antigens
    • Rowe DJ, Beverley PC. Characterization of breast cancer infiltrates using monoclonal antibodies to human leukocyte antigens. B J Cancer 1984;49:149-59.
    • (1984) B J Cancer , vol.49 , pp. 149-159
    • Rowe, D.J.1    Beverley, P.C.2
  • 10
    • 0021845777 scopus 로고
    • Mononuclear cells infiltrating human mammary carcinomas: Immunohistochemical analysis with monoclonal antibodies
    • Hurlimann J, Saraga P. Mononuclear cells infiltrating human mammary carcinomas: immunohistochemical analysis with monoclonal antibodies. Int J Cancer 1985;35: 753-62.
    • (1985) Int J Cancer , vol.35 , pp. 753-762
    • Hurlimann, J.1    Saraga, P.2
  • 12
    • 0023178579 scopus 로고
    • Immunohistochemical analysis of HLA antigens and mononuclear infiltrates of benign and malignant breast
    • Zuk JA, Walker RA. Immunohistochemical analysis of HLA antigens and mononuclear infiltrates of benign and malignant breast. J Path 1987;152:275-85.
    • (1987) J Path , vol.152 , pp. 275-285
    • Zuk, J.A.1    Walker, R.A.2
  • 13
    • 0024576588 scopus 로고
    • Characterization of T-lymphocyte subpopulations infiltrating primary breast cancer
    • Bilik R, Mor C, Hazaz B, Moroz C. Characterization of T-lymphocyte subpopulations infiltrating primary breast cancer. Canc Immun Immunoth 1989;28:143-7.
    • (1989) Canc Immun Immunoth , vol.28 , pp. 143-147
    • Bilik, R.1    Mor, C.2    Hazaz, B.3    Moroz, C.4
  • 14
    • 0025228577 scopus 로고
    • Quantitative immunohistochemical analysis of mononuclear infiltrates in breast carcinomas - Correlation with tumor differentiation
    • Naukkarinen A, Syrjanen KJ. Quantitative immunohistochemical analysis of mononuclear infiltrates in breast carcinomas - correlation with tumor differentiation. J Path 1990;160:217-22.
    • (1990) J Path , vol.160 , pp. 217-222
    • Naukkarinen, A.1    Syrjanen, K.J.2
  • 15
    • 0026567677 scopus 로고
    • Flow cytometric analysis of tumor infiltrating lymphocyte activation and tumor cell MHC class I and II expression in breast cancer patients
    • Whitford P, George WD, Campbell AM. Flow cytometric analysis of tumor infiltrating lymphocyte activation and tumor cell MHC class I and II expression in breast cancer patients. Canc Lett 1992;61:157-64.
    • (1992) Canc Lett , vol.61 , pp. 157-164
    • Whitford, P.1    George, W.D.2    Campbell, A.M.3
  • 16
    • 0017620693 scopus 로고
    • Immunopathology of breast cancer
    • Black MM. Immunopathology of breast cancer. Pathobiol Annu 1977;7:213-30.
    • (1977) Pathobiol Annu , vol.7 , pp. 213-230
    • Black, M.M.1
  • 17
    • 0033029667 scopus 로고    scopus 로고
    • The immunology and immunotherapy of breast cancer: An update
    • Hadden JW. The immunology and immunotherapy of breast cancer: an update. Int J Immunopharmacol 1999;21: 79-101.
    • (1999) Int J Immunopharmacol , vol.21 , pp. 79-101
    • Hadden, J.W.1
  • 18
    • 0031770891 scopus 로고    scopus 로고
    • Adjuvant treatment of breast cancer: A pilot immunochemotherapy study with CMF, interleukin-2 and interferon alpha
    • Tonini G, Nunziata C, Prete SP, Pepponi R, Turriziani M, Masci G, et al. Adjuvant treatment of breast cancer: a pilot immunochemotherapy study with CMF, interleukin-2 and interferon alpha. Cancer Immunol Immunother 1998;47: 157-66.
    • (1998) Cancer Immunol Immunother , vol.47 , pp. 157-166
    • Tonini, G.1    Nunziata, C.2    Prete, S.P.3    Pepponi, R.4    Turriziani, M.5    Masci, G.6
  • 19
    • 0032971662 scopus 로고    scopus 로고
    • Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: Results of a phase 1 clinical trial
    • Stewart AK, Lassam NJ, Quirt IC, Bailey DJ, Rotstein LE, Krajden M, et al. Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial. Gene Ther 1999;6: 350-63.
    • (1999) Gene Ther , vol.6 , pp. 350-363
    • Stewart, A.K.1    Lassam, N.J.2    Quirt, I.C.3    Bailey, D.J.4    Rotstein, L.E.5    Krajden, M.6
  • 20
    • 0033227839 scopus 로고    scopus 로고
    • Loss of tumorigenicity of human breast cancer cells engineered to produce IL-2, IL-4 or GM-CSF in nude mice
    • Maeda T, Matsubara H, Sugaya M, Miyazawa Y, Gunji Y, Ochiai T, et al. Loss of tumorigenicity of human breast cancer cells engineered to produce IL-2, IL-4 or GM-CSF in nude mice. Int J Oncol 1999;15:943-7.
    • (1999) Int J Oncol , vol.15 , pp. 943-947
    • Maeda, T.1    Matsubara, H.2    Sugaya, M.3    Miyazawa, Y.4    Gunji, Y.5    Ochiai, T.6
  • 21
    • 0033967184 scopus 로고    scopus 로고
    • High dose cyclophosphamide + carboplatin and interleukin-2 (IL-2) activated autologous stem cell transplantation followed by maintenance IL-2 therapy in metastatic breast carcinoma - A phase II study
    • Toh HC, McAfee SL, Sackstein R, Multani P, Cox BF, Garcia-Carbonero R, et al. High dose cyclophosphamide + carboplatin and interleukin-2 (IL-2) activated autologous stem cell transplantation followed by maintenance IL-2 therapy in metastatic breast carcinoma - a phase II study. Bone Marrow Transplant 2000;25:19-24.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 19-24
    • Toh, H.C.1    McAfee, S.L.2    Sackstein, R.3    Multani, P.4    Cox, B.F.5    Garcia-Carbonero, R.6
  • 22
    • 0033972453 scopus 로고    scopus 로고
    • Posttransplant adoptive immunotherapy with activated natural killer cells in patients with metastatic breast cancer
    • deMagalhaes-Silverman M, Donnenberg A, Lembersky B, Elder E, Lister J, Rybka W, et al. Posttransplant adoptive immunotherapy with activated natural killer cells in patients with metastatic breast cancer. J Immunother 2000;23: 154-60.
    • (2000) J Immunother , vol.23 , pp. 154-160
    • DeMagalhaes-Silverman, M.1    Donnenberg, A.2    Lembersky, B.3    Elder, E.4    Lister, J.5    Rybka, W.6
  • 23
    • 0033852076 scopus 로고    scopus 로고
    • Recombinant vaccinia virus encoding human MUC1 and IL2 as immunotherapy in patients with breast cancer
    • Scholl SM, Balloul JM, Le Goc G, Bizouarne N, Schatz C, Kieny MP, et al. Recombinant vaccinia virus encoding human MUC1 and IL2 as immunotherapy in patients with breast cancer. J Immunother 2000;23:570-80.
    • (2000) J Immunother , vol.23 , pp. 570-580
    • Scholl, S.M.1    Balloul, J.M.2    Le Goc, G.3    Bizouarne, N.4    Schatz, C.5    Kieny, M.P.6
  • 24
    • 0035863738 scopus 로고    scopus 로고
    • Complete regression of established spontaneous mammary carcinoma and the therapeutic prevention of genetically programmed neoplastic transition by IL-12/pulse IL-2: Induction of local T cell infiltration, Fas/Fas ligand gene expression, and mammary epithelial apoptosis
    • Wigginton JM, Park JW, Gruys ME, Young HA, Jorcyk CL, Back TC, et al. Complete regression of established spontaneous mammary carcinoma and the therapeutic prevention of genetically programmed neoplastic transition by IL-12/pulse IL-2: induction of local T cell infiltration, Fas/Fas ligand gene expression, and mammary epithelial apoptosis. J Immunol 2001;166:1156-68.
    • (2001) J Immunol , vol.166 , pp. 1156-1168
    • Wigginton, J.M.1    Park, J.W.2    Gruys, M.E.3    Young, H.A.4    Jorcyk, C.L.5    Back, T.C.6
  • 25
    • 0035254840 scopus 로고    scopus 로고
    • Pilot trial of interleukin-2 with granulocyte colony-stimulating factor for the mobilization of progenitor cells in advanced breast cancer patients undergoing high-dose chemotherapy: Expansion of immune effectors within the stem-cell graft and post-stem-cell infusion
    • Sosman JA, Stiff P, Moss SM, Sorokin P, Martone B, Bayer R, et al. Pilot trial of interleukin-2 with granulocyte colony-stimulating factor for the mobilization of progenitor cells in advanced breast cancer patients undergoing high-dose chemotherapy: expansion of immune effectors within the stem-cell graft and post-stem-cell infusion. J Clin Oncol 2001;19:634-44.
    • (2001) J Clin Oncol , vol.19 , pp. 634-644
    • Sosman, J.A.1    Stiff, P.2    Moss, S.M.3    Sorokin, P.4    Martone, B.5    Bayer, R.6
  • 26
    • 0034864743 scopus 로고    scopus 로고
    • Immunogene therapy with interleukin-2-secreting fibroblasts for intracerebrally metastasizing breast cancer in mice
    • Deshmukh P, Glick RP, Lichtor T, Moser R, Cohen ER. Immunogene therapy with interleukin-2-secreting fibroblasts for intracerebrally metastasizing breast cancer in mice. J Neurosurg 2001;94:287-92.
    • (2001) J Neurosurg , vol.94 , pp. 287-292
    • Deshmukh, P.1    Glick, R.P.2    Lichtor, T.3    Moser, R.4    Cohen, E.R.5
  • 27
    • 0031178815 scopus 로고    scopus 로고
    • Expansion of CD3+CD56+ lymphocytes correlates with induction of cytotoxicity by interleukin-2 gene transfer in human breast tumor cultures
    • Euhus DM, Kimura L, Arnold B. Expansion of CD3+CD56+ lymphocytes correlates with induction of cytotoxicity by interleukin-2 gene transfer in human breast tumor cultures. Ann Surg Oncol 1997;4:432-9.
    • (1997) Ann Surg Oncol , vol.4 , pp. 432-439
    • Euhus, D.M.1    Kimura, L.2    Arnold, B.3
  • 29
    • 0026425582 scopus 로고
    • Expression of HLA class I and II antigens in bronchogenic carcinomas: Its relationship to cellular DNA content and clinical-pathological parameters
    • Redondo M, Concha A, Oldiviela R, Cueto A, Gonzalez A, Garrido F, et al. Expression of HLA class I and II antigens in bronchogenic carcinomas: its relationship to cellular DNA content and clinical-pathological parameters. Cancer Res 1991;51:4948-54.
    • (1991) Cancer Res , vol.51 , pp. 4948-4954
    • Redondo, M.1    Concha, A.2    Oldiviela, R.3    Cueto, A.4    Gonzalez, A.5    Garrido, F.6
  • 30
    • 0029126118 scopus 로고
    • Different patterns of HLA-DR antigen expression in normal epithelium, hyperplastic and neoplastic malignant lesions of the breast
    • Concha A, Ruiz-Cabello F, Cabrera T, Nogales F, Collado A, Garrido F. Different patterns of HLA-DR antigen expression in normal epithelium, hyperplastic and neoplastic malignant lesions of the breast. Eur J Immunogenet 1995;22: 299-310.
    • (1995) Eur J Immunogenet , vol.22 , pp. 299-310
    • Concha, A.1    Ruiz-Cabello, F.2    Cabrera, T.3    Nogales, F.4    Collado, A.5    Garrido, F.6
  • 31
    • 0027487856 scopus 로고
    • Protective and curative potential of vaccination with interleukin-2-gene-transfected cells from a spontaneous mouse mammary adenocarcinoma
    • Cavallo F, Di Pierro F, Giovarelli M, Gulino A, Vacca A, Stoppacciaro A, et al. Protective and curative potential of vaccination with interleukin-2-gene-transfected cells from a spontaneous mouse mammary adenocarcinoma. Cancer Res 1993;53:5067-70.
    • (1993) Cancer Res , vol.53 , pp. 5067-5070
    • Cavallo, F.1    Di Pierro, F.2    Giovarelli, M.3    Gulino, A.4    Vacca, A.5    Stoppacciaro, A.6
  • 32
    • 0031759989 scopus 로고    scopus 로고
    • Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors
    • Addison CL, Bramson JL, Hitt MM, Muller WJ, Gauldie J, Graham FL. Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors. Gene Ther 1998;5:1400-9.
    • (1998) Gene Ther , vol.5 , pp. 1400-1409
    • Addison, C.L.1    Bramson, J.L.2    Hitt, M.M.3    Muller, W.J.4    Gauldie, J.5    Graham, F.L.6
  • 33
    • 0032549487 scopus 로고    scopus 로고
    • Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer
    • Putzer BM, Bramson JL, Addison CL, Hitt M, Siegel PM, Muller WJ, Graham FL. Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer. Hum Gene Ther 1998;9:707-18.
    • (1998) Hum Gene Ther , vol.9 , pp. 707-718
    • Putzer, B.M.1    Bramson, J.L.2    Addison, C.L.3    Hitt, M.4    Siegel, P.M.5    Muller, W.J.6    Graham, F.L.7
  • 34
    • 0032032264 scopus 로고    scopus 로고
    • A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model
    • Emtage PC, Wan Y, Bramson JL, Graham FL, Gauldie J. A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model. J Immunol 1998;160:2531-8.
    • (1998) J Immunol , vol.160 , pp. 2531-2538
    • Emtage, P.C.1    Wan, Y.2    Bramson, J.L.3    Graham, F.L.4    Gauldie, J.5
  • 35
    • 0029691138 scopus 로고    scopus 로고
    • In vivo cancer gene therapy with a recombinant interleukin-2 adenovirus vector
    • Toloza EM, Hunt K, Swisher S, McBride W, Lau R, Pang S, et al. In vivo cancer gene therapy with a recombinant interleukin-2 adenovirus vector. Cancer Gene Ther 1996;3:11-7.
    • (1996) Cancer Gene Ther , vol.3 , pp. 11-17
    • Toloza, E.M.1    Hunt, K.2    Swisher, S.3    McBride, W.4    Lau, R.5    Pang, S.6
  • 36
    • 0030863314 scopus 로고    scopus 로고
    • Anti-tumor effects of local irradiation in combination with peritumoral administration of low doses of recombinant interleukin-2 (rIL-2)
    • Jurgenliemk-Schulz IM, Renes IB, Rutgers DH, Everse LA, Bernsen MR, Den Otter W, et al. Anti-tumor effects of local irradiation in combination with peritumoral administration of low doses of recombinant interleukin-2 (rIL-2). Radiat Oncol Investig 1997;5:54-61.
    • (1997) Radiat Oncol Investig , vol.5 , pp. 54-61
    • Jurgenliemk-Schulz, I.M.1    Renes, I.B.2    Rutgers, D.H.3    Everse, L.A.4    Bernsen, M.R.5    Den Otter, W.6
  • 37
    • 0030816494 scopus 로고    scopus 로고
    • Local low-dose interleukin-2 induces systemic immunity when combined with radiotherapy of cancer. A pre-clinical study
    • Everse LA, Renes IB, Jurgenliemk-Schulz IM, Rutgers DH, Bernsen MR, Dullens HF, et al. Local low-dose interleukin-2 induces systemic immunity when combined with radiotherapy of cancer. A pre-clinical study. Int J Cancer 1997;72: 1003-7.
    • (1997) Int J Cancer , vol.72 , pp. 1003-1007
    • Everse, L.A.1    Renes, I.B.2    Jurgenliemk-Schulz, I.M.3    Rutgers, D.H.4    Bernsen, M.R.5    Dullens, H.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.