Up-regulation of granulomatous inflammation in interleukin-6 knockout mice infected with Rhodococcus aurantiacus

Immunology

Volumn 110, Issue 4, 2003, Pages 501-506

  Yimin, ^a   Kohanawa, Masashi ^a   Minagawa, Tomonori ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 6; MONOCLONAL ANTIBODY; RECOMBINANT INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GORDONA AURANTIACA; GRANULOMATOUS INFLAMMATION; IN VIVO STUDY; KNOCKOUT MOUSE; LIVER; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; RHODOCOCCUS; SPLEEN;

ACTINOMYCETALES INFECTIONS; ANIMALS; ANTIBODIES, MONOCLONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GRANULOMA; IMMUNOSUPPRESSION; INFLAMMATION; INTERFERON TYPE II; INTERLEUKIN-6; KINETICS; LIVER; MICE; MICE, KNOCKOUT; NECROSIS; RHODOCOCCUS; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0348112448     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2003.01762.x     Document Type: Article

References (26)

1. Kopf M, Baumann H, Freer G et al. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature 1994; 368:339-42.
2. Van Snick J. Interleukin-6: an overview. Annu Rev Immunol 1990; 8:253-78.
3. Appelberg R, Castro AG, Pedrosa J, Minoprio P. Role of interleukin-6 in the induction of protective T cells during mycobacterial infections in mice. Immunol 1994; 82:361-4.
4. Denis M, Gregg EO. Recombinant tumor necrosis factor-alpha decreases whereas recombinant interleukin-6 increases growth of a virulent strain of Mycobacterium avium in human macrophages. Immunol 1990; 71:139-41.
5. Blum AM, Metwali A, Elliott D, Li J, Sandor M, Weinstock JV. IL-6-deficient mice form granulomas in murine Schistosomiasis that exhibit an altered B cell response. Cellular Immunol 1998; 188:64-72.
6. Dalrymple SA, Lucian LA, Slattery R, McNeil T, Aud DM, Fuchion S, Lee F, Murray R. Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: Correlation with inefficient neutrophilia. Infect Immun 1995; 63:2262-8.
7. Chensue SW, Warmington KS, Ruth JH, Lincoln P, Kunkel SL. Cytokine function during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. J Immunol 1995; 154:5969-76.
8. Chensue SW, Warmington KS, Ruth JH, Lukacs N, Kunkel SL. Mycobacterial and schistosomal antigen-elicited granuloma formation in IFN-γ and IL-4 knockout mice: analysis of local and regional cytokine and chemokine networks. J Immunol 1997; 159:3565-73.
9. Gordon S, Keshav S, Stein M. BCG-induced granuloma formation in murine tissues. Immunobiol 1994; 191:369-77.
10. Manca C, Tsenova LC, Barry CE III et al. Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates. J Immunol 1999; 162:6740-6.
11. Asano M, Nakane A, Minagawa T. Endogenous gamma interferon is essential in granuloma formation induced by glycolipid-containing mycolic acid in mice. Infect Immun 1993; 61:2872-8.
12. + T cells in granuloma formation of Rhodococcus aurantiacus-infected mice. Microbiol Immunol 1995; 39:499-507.
13. Spitalny GL, Havell EA. Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities. J Exp Med 1984; 159:1560-5.
14. Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE. Strategies of anti-cytokine monoclonal antibody development, immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev 1992; 127:5-24.
15. Nakane A, Minagawa M, Kohanawa M, Chen Y, Sato H, Moriyama M, Tsuruoka N. Interactions between endogenous gamma interferon and tumor necrosis factor in host resistance against primary and secondary Listeria monocytogenes infections. Infect Immun 1989; 57:3331-7.
16. Nakane A, Numata A, Minagawa T. Endogenous tumor necrosis factor, interleukin-6, and gamma interferon levels during Listeria monocytogenes infection in mice. Infect Immun 1992; 60:523-8.
17. Yimin, Kohanawa M, Sato Y, Minagawa T. Role of T cells in granuloma formation induced by Rhodococcus aurantiacus is independent of their interferon-gamma production. J Med Microbiol 2001; 50:688-94.
18. Kaneko H, Yamada H, Mizuno S, Udagawa T, Kazumi Y, Sekikawa K, Sugawara I. Role of tumor necrosis factor-α in mycobacterium-induced granuloma formation in tumor necrosis factor-α-deficient mice. Laboratory Invest 1999; 79:379-86.
19. Chen YL, Yu CK, Lei HY. Propionibacterium acnes induces acute TNFα-mediated apoptosis of hepatocytes followed by inflammatory T-cell-mediated granulomatous hepatitis in mice. J Biomed Sci 1999; 6:349-56.
20. Cao Q, Batey R, Pang G, Russell A, Clancy R. IL-6, IFN-γ and TNF-α production by liver-associated T cells and acute liver injury in rats administered concanavalin A. Immunol Cell Biol 1998; 76:542-9.
21. Esparza I, Mannel D, Ruppel A, Falk W, Krammer PH. Interferon-γ and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni. J Exp Med 1987; 166:589-94.
22. Smith D, Hansch H, Bancroft G, Ehlers S. T-cell-independent granuloma formation in response to Mycobacterium avium: role of tumour necrosis factor-α and interferon-γ. Immunol 1997; 92:413-21.
23. Hunter CA, Subauste CS, Van Cleave VH, Remington JS. Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: Regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect Immun 1994; 62:2818-24.
24. Tripp CS, Wolf SF, Unanue ER. Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc Natl Acad Sci USA 1993; 90:3725-9.
25. Liu Z, Simpson RJ, Cheers C. Role of IL-6 in activation of T cells for acquired cellular resistance to Listeria monocytogenes. J Immunol 1994; 152:5375-80.
26. Mizuhara H, O'Neill E, Seki N et al. T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J Exp Med 1994; 179:1529-37.