Reduced Bone Mineral Density in Early Rheumatoid Arthritis Is Associated with Radiological Joint Damage at Baseline and after 2 Years in Women

Journal of Rheumatology

Volumn 30, Issue 12, 2003, Pages 2590-2596

  Forslind, Kristina ^a   Keller, Catharina ^a   Svensson, Björn ^a   Hafström, Ingiäld ^b  

^a Section of Rheumatology   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Bone mineral density; Gender; Joint destruction; Rheumatoid arthritis

Indexed keywords

C REACTIVE PROTEIN;

ADULT; ARTICLE; BONE DENSITY; BONE MASS; BONE MINERAL; DISEASE ACTIVITY; FEMALE; FOOT RADIOGRAPHY; HAND RADIOGRAPHY; HUMAN; JOINT INJURY; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; OSTEOPOROSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUESTIONNAIRE; RHEUMATOID ARTHRITIS; STANFORD HEALTH ASSESSMENT QUESTIONNAIRE;

ADULT; AGED; AGED, 80 AND OVER; ARTHRITIS, RHEUMATOID; ARTHROGRAPHY; BONE DENSITY; DENSITOMETRY, X-RAY; DISABILITY EVALUATION; DISEASE PROGRESSION; FEMALE; HEALTH STATUS; HIP JOINT; HUMANS; JOINTS; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; QUESTIONNAIRES; SEVERITY OF ILLNESS INDEX;

EID: 0348109368     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Deodhar AA, Woolf AD. Bone mass measurement and bone metabolism in rheumatoid arthritis: a review. Br J Rheumatol 1996;35:309-23.
2. Westhovens R, Dequeker J. Rheumatoid arthritis and osteoporosis. Z Rheumatol 2000;59:133-8.
3. Martin JC, Munro R, Campbell MK, Reid DM. Effects of disease and corticosteroids on appendicular bone mass in postmenopausal women with rheumatoid arthritis: comparison with axial measurements. Br J Rheumatol 1997;36:43-9.
4. Hansen M, Florescu A, Stoltenberg M, et al. Bone loss in rheumatoid arthritis. Scand J Rheumatol 1996;25:367-76.
5. Gough A, Sambrook P, Devlin J, et al. Osteoclastic activation is the principal mechanism leading to secondary osteoporosis in rheumatoid arthritis. J Rheumatol 1998;25:1282-9.
6. Hall GM, Spector TD, Griffin AJ, Jawad ASM, Hall ML, Doyle DV. The effect of rheumatoid arthritis and steroid therapy on bone mineral density in postmenopausal women. Arthritis Rheum 1993;36:1510-6.
7. Haugeberg G, Uhlig T, Falch JA, Halse JI, Kvien TK. Bone mineral density and frequency of osteoporosis in female patients with rheumatoid arthritis. Arthritis Rheum 2000;43:522-30.
8. Sinigaglia L, Nervetti A, Mela Q, et al. A multicenter cross-sectional study on bone mineral density in rheumatoid arthritis. J Rheumatol 2000;27:2582-9.
9. Compston JE, Vedi S, Mellish RWE, Croucher P, O'Sullivan MM. Reduced bone formation in non-steroid treated patients with rheumatoid arthritis. Ann Rheum Dis 1989;48:483-7.
10. Compston JE, Vedi S, Croucher PI, Garrahan NJ, O'Sullivan MM. Bone turnover in non-steroid treated rheumatoid arthritis. Ann Rheum Dis 1994;53:163-6.
11. Gough AKS, Peel NFA, Eastell R, Holder RL, Lilley J, Emery P. Excretion of pyridinium crosslinks correlates with disease activity and appendicular bone loss in early rheumatoid arthritis. Ann Rheum Dis 1994;53:14-7.
12. Cunnane G, FitzGerald O, Hummel KM, Gay RE, Gay S, Bresnihan B. Collagenase, cathepsin B and cathepsin L gene expression in the synovial membrane of patients with early inflammatory arthritis. Rheumatology Oxford 1999;38:34-42.
13. Sambrook PN. The skeleton in rheumatoid arthritis: Common mechanisms for bone erosion and osteoporosis? J Rheumatol 2000;27:2541-2.
14. Keller C, Hafström I, Svensson B. Bone mineral density in women and men with early rheumatoid arthritis. Scand J Rheumatol 2001;30:213-20.
15. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
16. Svensson B, Schaufelberger C, Teleman A, Theander J, for the BARFOT study group. Remission and response to early treatment of RA assessed by the Disease Activity Score. Rheumatology Oxford 2000;39:1031-6.
17. Lunar Corporation. Operator's manual, expert-XL, version 1.7. Madison, WI: Lunar Corporation; 1998.
18. World Health Organization. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. WHO Technical Report Series, 843. Geneva: WHO; 1994.
19. Kanis JA, Melton LJ III, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res 1994;9:1137-41.
20. Larsen A, Dale K, Eek M. Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films. Acta Radiol Diagn 1977;18:481-91.
21. Prevoo MLL, van't Hof MA, Kuper HH, van Leeuwven MA, van de Putte LBA, van Riel PLCM. Modified disease activity scores that include twenty-eight joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;39:44-8.
22. Ekdahl C, Eberhardt K, Andersson SI, Svensson B. Assessing disability in patients with rheumatoid arthritis, use of a Swedish version of the Stanford Health Assessment Questionnaire. Scand J Rheumatol 1988;17:263-71.
23. Fries JF, Spitz P, Kraines RG, Holman HR. Measurement of patient outcome in arthritis. Arthritis Rheum 1980;23:137-45.
24. Möttönen TT. Prediction of erosiveness and rate of development of new erosions in early rheumatoid arthritis. Ann Rheum Dis 1988;47:648-53.
25. van der Heijde DMFM, van Riel PLCM, van Leuween MA, van't Hof MA, van Rijswijk MH, van de Putte LBA. Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis. A prospective followup study of 147 patients. Br J Rheumatol 1992;31:519-25.
26. van der Heide A, Remme CA, Hofman DM, Jacobs JWG, Bijlsma JWJ. Prediction of progression of radiologic damage in newly diagnosed rheumatoid arthritis. Arthritis Rheum 1995;38:1446-74.
27. Combe B, Dougados M, Goupille P, et al. Prognostic factors for radiographic damage in early rheumatoid arthritis. A multiparameter prospective study. Arthritis Rheum 2001;44:1736-43.
28. Scott DL, Grindulis KA, Struthers GR, Coulton BL, Popert AJ, Bacon PA. Progression of radiological changes in rheumatoid arthritis. Ann Rheum Dis 1984;43:8-17.
29. Plant MJ, Saklatavla J, Borg AA, Jones PW, Dawes PT. Measurement and prediction of radiological progression in early rheumatoid arthritis. J Rheumatol 1994;21:1808-13.
30. Bromley M, Woolley DE. Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint. Arthritis Rheum 1984;27:968-75.
31. Gravallese EM, Harada Y, Wang JT, Gorn AH, Thornhill TS, Goldring SR. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol 1998;152:943-51.
32. Rothe L, Collin-Osdoby P, Chen Y, et al. Human osteoclasts and osteoclast-like cells synthesize and release high basal and inflammatory stimulated levels of the potent chemokine interleukin-8. Endocrinology 1998;139:4353-63.
33. Nishiura H, Tanaka J, Takeya M, Tsukano M, Kambara T, Imamura T. IL-8/NAP-1 is the major T-cell chemoattractant in synovial tissues of rheumatoid arthritis. Clin Immunol Immunopathol 1996;80:179-84.
34. Arend WP, Dayer J-M. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Review. Arthritis Rheum 1995;38:151-60.
35. Feldmann M, Brennan FM, Maini R. Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 1996;14:397-440.
36. Coste J, Spira A, Clerc D, Paolaggi JB. Prediction of articular destruction in rheumatoid arthritis: Disease activity markers revisited. J Rheumatol 1997;24:28-34.
37. van Leeuwen MA, van der Heijde DMFM, van Rijswijk MH, et al. Interrelationship of outcome measures and process variables in early rheumatoid arthritis. A comparison of radiological damage, physical disability, joint counts, and acute phase reactants. J Rheumatol 1994;21:425-9.
38. Wolfe F, Sharp JT. Radiographic outcome of recent-onset rheumatoid arthritis: A 19-year study of radiographic progression. Arthritis Rheum 1998;41:1571-82.
39. Graudal N, Tarp U, Jurik AG, et al. Inflammatory patterns in rheumatoid arthritis estimated by the number of swollen and tender joints, the erythrocyte sedimentation rate, and hemoglobin: Longterm course and association to radiographic progression. J Rheumatol 2000;27:47-57.
40. Mulherin D, Fitzgerald O, Bresnihan B. Clinical improvement and radiological deterioration in rheumatoid arthritis: evidence that the pathogenesis of synovial inflammation and articular erosion may differ. Br J Rheumatol 1996;35:1263-8.
41. van der Heijde DM, van Riel PL, van Leeuwen MA, van't Hof MA, van Rijswijk MH, van de Putte LB. Older versus younger onset rheumatoid arthritis: results at onset and after 2 years of a prospective followup study of early rheumatoid arthritis. J Rheumatol 1991;18:1285-9.
42. Kuiper S, van Gestel AM, Swinkels HL, de Boo TM, da Silva JA, van Riel PL. Influence of sex, age, and menopausal state on the course of early rheumatoid arthritis. J Rheumatol 2001;28:1809-16.
43. Masi AT. Sex hormones and rheumatoid arthritis: cause or effect relationships in a complex pathophysiology? Clin Exp Rheumatol 1995;13:227-40.
44. Albright F, Smith PH, Richardsson AM. Postmenopausal osteoporosis. JAMA 1948;116:2465-74.
45. Bijlsma JW, van den Brink HR. Estrogens and rheumatoid arthritis. Review. Am J Reprod Immunol 1992;28:231-4.
46. Forsblad H, Larsen A, Mattsson L, et al. Beneficial effects of hormone replacement therapy in rheumatoid arthritis [abstract]. Ann Rheum Dis 2002;61 Suppl 1:45.
47. Cenci S, Weitzmann MN, Roggia C, et al. Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-a. J Clin Invest 2000;106:1229-37.
48. Tengstrand B, Carlström C, Hafström I. Bioavailable testosterone in men with rheumatoid arthritis - high frequency of hypogonadism. Rheumatology Oxford 2002;41:285-9.
49. Tengstrand B, Hafström I. Bone mineral density in men with rheumatoid arthritis is associated with erosive disease and sulphasalazine treatment but not with sex hormones. J Rheumatol 2002;29:2299-305.
50. Compston JE. Sex steroids and bone. Physiol Rev 2001;81:419-47.
51. American College of Rheumatology Subcommittee on Rheumatoid Arthritis Guidelines. Guidelines for the management of rheumatoid arthritis. Arthritis Rheum 2002;46:328-46.
52. Stenger AAME, van Leeuwen MA, Houtman PM, et al. Early effective suppression of inflammation in rheumatoid arthritis reduces radiographic progression. Br J Rheumatol 1998;37:1157-63.
53. Verhoeven AC, Boers M, te Koppele JM, et al. Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone. Rheumatology Oxford 2001;40:1231-7.
54. Redlich K, Hayer S, Maier A, et al. Tumor necrosis factor a-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin. Arthritis Rheum 2002;46:785-92.