Osmotic demyelination syndrome: A potentially avoidable disaster

QJM: An International Journal of Medicine

Volumn 96, Issue 12, 2003, Pages 935-947

  Lin, S H ^a   Hsu, Y J ^a   Chiu, J S ^a   Chu, S J ^a   Davids, M R ^b   Halperin, Mitchell L ^c  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b STELLENBOSCH UNIVERSITY   (South Africa)

^c ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; BICARBONATE; CALCIUM SENSING RECEPTOR; CHLORIDE ION; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DIURETIC AGENT; GLUCOSE; HYDROCORTISONE; INSULIN; PHYSOSTIGMINE; POTASSIUM ION; SODIUM; SODIUM CHLORIDE; VASOPRESSIN; WATER;

ACUTE RESPIRATORY FAILURE; ADDISON DISEASE; ADRENAL INSUFFICIENCY; ADULT; ANOREXIA; ARTICLE; CASE REPORT; CHRONIC DISEASE; DEMYELINATING DISEASE; DISEASE ASSOCIATION; DIURESIS; EXTRACELLULAR FLUID; FATIGUE; FEMALE; HENLE LOOP; HUMAN; HYPERKALEMIA; HYPOGLYCEMIA; HYPONATREMIA; HYPOTENSION; HYPOVOLEMIA; HYPOXIA; KIDNEY COLLECTING TUBULE; KIDNEY DISTAL TUBULE; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; MUSCLE WEAKNESS; MYASTHENIA GRAVIS; NAUSEA; NUCLEAR MAGNETIC RESONANCE IMAGING; OSMOSIS; POTASSIUM EXCRETION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK MANAGEMENT; SODIUM BLOOD LEVEL; SODIUM URINE LEVEL; TACHYCARDIA; TREATMENT PLANNING; URINE FLOW RATE; VASOPRESSIN RELEASE; VOMITING; WEIGHT REDUCTION;

EID: 0348013216     PISSN: 14602725     EISSN: None     Source Type: Journal    
DOI: 10.1093/qjmed/hcg159     Document Type: Article

References (27)

1. Sterns RH, Silver SM, Spital A. Hyponatremia. In: Seldin DW, Giebisch G, eds. The Kidney: Physiology & Pathophysiology. Philadelphia PA. Lippincott Williams & Wilkins, 2000: 1217-38.
2. Porte DJ. Sympathetic regulation of insulin secretion. Arch Intern Med 1969; 123:252-60.
3. Adrogue HJ, Madias NE. Changes in plasma potassium concentration during acute acid-base disturbances. Am J Med 1981; 71:456-67.
4. + channel by aldosterone: Open questions and emerging answers. Kidney Int 2000; 57:12 70-6.
5. Lin S-H, Davids MR, Halperin ML. Hypokalaemia and paralysis. Q J Med 2003; 96:161-9.
6. Halperin ML, Kamel KS. Potassium. Lancet 1998; 352: 135-42.
7. Halperin ML, Bichet DG, Oh MS. Integrative physiology of basal water permeability in the distal nephron: implications for the syndrome of inappropriate secretion of antidiuretic hormone. Clin Nephrol 2001; 56:339-45.
8. Carlotti APCP, Bohn D, Mallie J-P, Halperin ML. Tonicity balance and not electrolyte-free water calculations more accurately guide therapy for acute changes in natremia. intensive Care Med 2001; 27:921-4.
9. Schreiber MS, Halperin ML. Paleolithic curriculum: Figure it out (with the help of experts). Adv Physiol Edu 1998; 20:S185-94.
10. Sonnenberg H. Renal regulation of salt balance: a primer for non-purists. Pediatr Nephrol 1990; 4:354-7.
11. Oliver WJ, Cohen EL, Neel JV. Blood pressure, sodium intake, and sodium related hormones in Yanomamo Indians, a 'No-Salt' culture. Circulation 1975; 52:146-51.
12. Taubes G. The (political) science of salt. Science 1998; 281:898-907.
13. Singh S, Bohn D, Cusimano M, Rutka JT, Halperin ML. Cerebral salt wasting; truths, fallacies, theories and challenges. Crit Care Med 2002; 30:2575-9.
14. Halperin ML, Goldstein MB. Fluid, Electrolyte and Acid-Base physiology; a problem-based approach. Philadelphia, WB Saunders, 1998.
15. Hebert SC. Extracellular calcium-sensing receptor: Implications for calcium and magnesium handling in the kidney. Kidney Int 1996; 50:2129-39.
16. Rotin D. Regulation of the epithelial sodium channel (ENaC) by accessory proteins. Curr Opin Nephrol Hypert 2000; 9:529-34.
17. Halperin ML, Kamel KS. Dynamic interactions between integrative physiology and molecular medicine: the key to understand the mechanism of action of aldosterone in the kidney. Can J Physiol Pharmacol 2000; 78:587-594.
18. Rossier BC. Cum Grano Salis: The epithelial sodium channel and the control of blood pressure. J Am Soc Nephrol 1997; 8:980-92.
19. Carlisle EJF, Donnelly SM, Ethier J, Quaggin SE, Kaiser U, Vasuvattakul S, et al. Modulation of the secretion of potassium by accompanying anions in humans. Kidney Int 1991; 39:1206-12.
20. Ecelbarger CA, Nielsen S, Olson BR, Murase T, Baker EA, Knepper MA, et al. Role of renal aquaporins in escape form vasopressin-induced antidiuresis in rat. J Clin Invest 1997; 99:1852-63.
21. McCance RA. Medical problems in mineral metabolism. III. Experimental human salt deficiency. Lancet 1936; 230:823-30.
22. Soupart A, Decaux G. Therapeutic recommendations for management of severe hyponatremia: current concepts on pathogenesis and prevention of neurologic complications. Clin Nephrol 1996; 46:149-69.
23. Gowrishankar M, Lin SH, Mallie JP, Oh MS, Halperin ML. Acute hyponatremia in the perioperative period: Insights into its pathophysiology and recommendations for management. Clin Nephrol 1998; 50:352-60.
24. Agre P, Preston GM, Smith BL, Jung JS, Raina S, Moon C, et al. Aquaporin CHIP: The archetpyal molecular water channel. Am J Physiol 1993; 265:F463-76.
25. Verbalis JG, Gullans SR. Rapid correction of hyponatremia produces differential effects on brain osmolyte reaccumulation in rats. Brain Res 1993; 606:19-27.
26. Lohr JW. Osmotic demyelination syndrome following correction of hyponatremia: association with hypokalemia. Am J Med 1994; 96:408-13.
27. Bahr M, Sommer N, Peterson D, Wietholter H, Dichgans J. Central pontine myelinolysis associated with low potassium levels in alcoholism. J Neurol 1990; 237:275-6.