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Volumn 12, Issue 2, 2003, Pages 69-86

Synthesis and anti-inflammatory activity determinations of N-[substituted benzoyl(phenylsulfonyl)amino]-5-ethyl-1,2,3,6-tetrahydropyridines

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ANTIINFLAMMATORY AGENT; CARRAGEENAN; INDOMETACIN; N (METHYLBENZENESULFONYLAMINO) 5 ETHYL 1,2,3,6 TETRAHYDROPYRIDINE; PYRIDINE DERIVATIVE; SODIUM BOROHYDRIDE; UNCLASSIFIED DRUG;

EID: 0348011470     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (22)
  • 1
    • 0347880245 scopus 로고
    • Meriam-Webster Inc. Publishers, Springfield, Massachusetts
    • Meriam Webster's Medical Desk Dictionary. Meriam-Webster Inc. Publishers, Springfield, Massachusetts 1993, 335.
    • (1993) Meriam Webster's Medical Desk Dictionary , pp. 335
  • 2
    • 0015237292 scopus 로고
    • Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs
    • Vane, J.R. Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs. Nature (London) New Biol. 1971, 231, 232-235.
    • (1971) Nature (London) New Biol. , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 3
    • 0015237275 scopus 로고
    • Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets
    • Smith, J.B.; Willis, A.L.; Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets. Nature (London) New Biol. 1971, 231, 235-237.
    • (1971) Nature (London) New Biol. , vol.231 , pp. 235-237
    • Smith, J.B.1    Willis, A.L.2
  • 4
    • 0004043489 scopus 로고
    • John Wiley & Son, Inc., New York
    • st ed., John Wiley & Son, Inc., New York, 1985.
    • (1985) st Ed.
    • Lombardino, J.G.1
  • 5
    • 0032169090 scopus 로고    scopus 로고
    • 3-(5-Alkylamino-4-isoxazolyl) 1,2,5,6-tetrahydropyridines: A Novel Class of Central Nicotinic Receptor Ligands
    • Olesen, P.H.; Swedberg, M.D.B.; Rimvall, K. 3-(5-Alkylamino-4-isoxazolyl) 1,2,5,6-tetrahydropyridines: A Novel Class of Central Nicotinic Receptor Ligands. Bioog. Med. Chem. 1998, 6, 1623-1629.
    • (1998) Bioog. Med. Chem. , vol.6 , pp. 1623-1629
    • Olesen, P.H.1    Swedberg, M.D.B.2    Rimvall, K.3
  • 6
    • 0032937826 scopus 로고    scopus 로고
    • In vivo muscarinic binding of 3-(alkylthio)-3-thiadiazolyl tetrahydropyridines
    • Kiesewetter, D.O.; Carson, R.E.; Jagoda, E.M.; Herscovitch, P.; Eckelman, W.C. In vivo muscarinic binding of 3-(alkylthio)-3-thiadiazolyl tetrahydropyridines. Synapse. 1999, 31(1), 29-40.
    • (1999) Synapse , vol.31 , Issue.1 , pp. 29-40
    • Kiesewetter, D.O.1    Carson, R.E.2    Jagoda, E.M.3    Herscovitch, P.4    Eckelman, W.C.5
  • 7
    • 0034051811 scopus 로고    scopus 로고
    • Evaluation of blood-brain barrier passage of muscarine M1 agonist and a series of analogous tetrahydropyridines measured by in vivo microdialysis
    • Sveigaard, H.H.; Dalgaard, L. Evaluation of blood-brain barrier passage of muscarine M1 agonist and a series of analogous tetrahydropyridines measured by in vivo microdialysis. Pharm Res. 2000, 77(1), 70-76.
    • (2000) Pharm Res. , vol.77 , Issue.1 , pp. 70-76
    • Sveigaard, H.H.1    Dalgaard, L.2
  • 8
    • 0001496694 scopus 로고
    • A Primate Model of Parkinsonism: Selective Destructive Dopamiergic Neurons in the Pars Compacta of the Substantia Nigra by N-methyl-4-Phenyl-1,2,3, 6-tetrahydropyridine
    • Burns, R.S.; Chiueh, C.C.; Markey, S.P.; Ebert, M.H.; Jacobowitz, D.M.; Kopin, I.J. A Primate Model of Parkinsonism: Selective Destructive Dopamiergic Neurons in the Pars Compacta of the Substantia Nigra by N-methyl-4-Phenyl-1,2,3, 6-tetrahydropyridine. Proc. Natl. Acad. Sci. 1983, 80, 4546-4550.
    • (1983) Proc. Natl. Acad. Sci. , vol.80 , pp. 4546-4550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 9
    • 0036315924 scopus 로고    scopus 로고
    • N. Synthesis and Biological Evaluation of MAO-A Selective 1,4-Disubstituted-1,2,3,6-tetrahydropyridinyl Substrates
    • Bissel, P.; Bigley, M.C.; Castagnoli, K.; Castagnoli Fr.; N. Synthesis and Biological Evaluation of MAO-A Selective 1,4-Disubstituted-1,2,3,6- tetrahydropyridinyl Substrates. Bioorg. Med Chem. 2002, 10(9), 3031-3041.
    • (2002) Bioorg. Med Chem. , vol.10 , Issue.9 , pp. 3031-3041
    • Bissel, P.1    Bigley, M.C.2    Castagnoli, K.3    Castagnoli, Fr.4
  • 10
    • 0036166111 scopus 로고    scopus 로고
    • Identification of metabolites of flourine-18-labeled M2 muscarinic receptor agonist, 3-3-[-flouropropyl)thio]-1,2,5-thiadiazol-4-yl)-1,2,5,6- tetrahydro-1-methylpyridine, produced by human and rat hepatocytes
    • Ma, Y.; Loesewetter, D.O.; Kagpda, E.M.; Huang, B.X.; Eckelman, W.C. Identification of metabolites of flourine-18-labeled M2 muscarinic receptor agonist, 3-3-[-flouropropyl)thio]-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1- methylpyridine, produced by human and rat hepatocytes. J. Chromat. B. 2002, 766(2), 319-329.
    • (2002) J. Chromat. B. , vol.766 , Issue.2 , pp. 319-329
    • Ma, Y.1    Loesewetter, D.O.2    Kagpda, E.M.3    Huang, B.X.4    Eckelman, W.C.5
  • 12
    • 0020055910 scopus 로고
    • Synthesis of N-(carbonylamino)-1,2,3,6-tetrahydropyridines with Analgesic, Anti-inflammatory, and Hyperglycemic Activity
    • Yeung, J.M.; Corleto, L.A.; Knaus, E.E. Synthesis of N-(carbonylamino)-1, 2,3,6-tetrahydropyridines with Analgesic, Anti-inflammatory, and Hyperglycemic Activity. J. Med. Chem., 1982, 25(2), 191-195.
    • (1982) J. Med. Chem. , vol.25 , Issue.2 , pp. 191-195
    • Yeung, J.M.1    Corleto, L.A.2    Knaus, E.E.3
  • 13
    • 0026787843 scopus 로고
    • Synthesis and pharmacological evaluation of some N-[pyridyl(phenyl) carbonylamino]methyl-1,2,3,6-tetrahydropyridines
    • Redda, K.K.; Rao, K.N.; Heiman, A.S.; Melles, H. Synthesis and pharmacological evaluation of some N-[pyridyl(phenyl)carbonylamino]methyl-1,2,3, 6-tetrahydropyridines, J. Pharm. Sci., 1992, 81, 463-466.
    • (1992) J. Pharm. Sci. , vol.81 , pp. 463-466
    • Redda, K.K.1    Rao, K.N.2    Heiman, A.S.3    Melles, H.4
  • 14
    • 0025875064 scopus 로고
    • Synthesis and anti-inflammatory activities of some N-[pyridyl(phenyl) carbonylamino]-tert-butyl/phenyl-1,2,3,6-tetrahydropyridines
    • Redda, K.K.; Rao, K.N.; Heiman, A.S.; Onayemi, F.Y.; Clark, J.B. Synthesis and anti-inflammatory activities of some N-[pyridyl(phenyl) carbonylamino]-tert-butyl/phenyl-1,2,3,6-tetrahydropyridines, Chem. Pharm. Bul., 1991, 39, 786-791.
    • (1991) Chem. Pharm. Bul. , vol.39 , pp. 786-791
    • Redda, K.K.1    Rao, K.N.2    Heiman, A.S.3    Onayemi, F.Y.4    Clark, J.B.5
  • 15
    • 0032450091 scopus 로고    scopus 로고
    • The pharmacological evaluations of some N-[pyridyl-(phenyl)carbonylamino] hydroxypropyl-1,2,3,6-tetrahy dropyridi nes as potential anti-inflammatory agents
    • Wilson, T.; Onubogu, U.; Kode, R.; Redda, K. The pharmacological evaluations of some N-[pyridyl-(phenyl)carbonylamino]hydroxypropyl-1,2,3,6- tetrahy dropyridi nes as potential anti-inflammatory agents. Drugs Exptl. Clin. Res., 1998, 24, 165-172.
    • (1998) Drugs Exptl. Clin. Res. , vol.24 , pp. 165-172
    • Wilson, T.1    Onubogu, U.2    Kode, R.3    Redda, K.4
  • 16
    • 84986451822 scopus 로고
    • Synthesis of some N-[Pyridyl(phenyl)-carbonylamino]-alkyl-1,2,3,6- tetrahydropyridines
    • Redda, K.K.; Melles, H.; Kode, R.N. Synthesis of some N-[Pyridyl(phenyl)-carbonylamino]-alkyl-1,2,3,6-tetrahydropyridines. J. Heterocyclic Chem. 1990, 27, 1041.
    • (1990) J. Heterocyclic Chem. , vol.27 , pp. 1041
    • Redda, K.K.1    Melles, H.2    Kode, R.N.3
  • 17
    • 0029898205 scopus 로고    scopus 로고
    • The Synthesis of Several N-(Substituted phenylcarbonylamino)-4-(3- cyclohexenyl) 1-2-3-6-tetrahydropyridines as Potential Anti-inflammatory Agents
    • Pelle, C.J.; Okoro, C.O.; Wilson, T.L.; Onubogu, U.C.; Yoon, K.J.; Redda, K.K. The Synthesis of Several N-(Substituted phenylcarbonylamino)-4-(3- cyclohexenyl) 1-2-3-6-tetrahydropyridines as Potential Anti-inflammatory Agents. Synthetic Comm., 1996, 20(14), 2703-2714.
    • (1996) Synthetic Comm. , vol.20 , Issue.14 , pp. 2703-2714
    • Pelle, C.J.1    Okoro, C.O.2    Wilson, T.L.3    Onubogu, U.C.4    Yoon, K.J.5    Redda, K.K.6
  • 18
    • 0002653595 scopus 로고    scopus 로고
    • Synthesis and Anti-inflammatory activity determinations of some N-(Substituted phenylcarbonylamino)-4-(1-hydroxymethyl-phenyl)-1,2,3,6- tetrahydropyridines
    • Okoro, C.O.; Wilson, T.L.; Choi, J.O.; Redda, K.K. Synthesis and Anti-inflammatory activity determinations of some N-(Substituted phenylcarbonylamino)-4-(1-hydroxymethyl-phenyl)-1,2,3,6-tetrahydropyridines. Med. Chem. Res., 1997, 7(1), 1-15.
    • (1997) Med. Chem. Res. , vol.7 , Issue.1 , pp. 1-15
    • Okoro, C.O.1    Wilson, T.L.2    Choi, J.O.3    Redda, K.K.4
  • 19
    • 0032957829 scopus 로고    scopus 로고
    • Synthesis and Biological Evaluations of N-(Substituted benzoylamino)-5-carbethoxymethy.-1,2,3,6-tetrahydropyridines as Potential Anti-inflammatory and Hyperglycemic Agents
    • Okoro, C.O.; Yoon, K.J.; Wilson, T.L.; Onubogu, U.C.; Eckford, T.S.; Redda, K.K. Synthesis and Biological Evaluations of N-(Substituted benzoylamino)-5-carbethoxymethy.-1,2,3,6-tetrahydropyridines as Potential Anti-inflammatory and Hyperglycemic Agents. Med Chem. Res.; 1999, 9(2), 133-148.
    • (1999) Med Chem. Res. , vol.9 , Issue.2 , pp. 133-148
    • Okoro, C.O.1    Yoon, K.J.2    Wilson, T.L.3    Onubogu, U.C.4    Eckford, T.S.5    Redda, K.K.6
  • 20
    • 0033926564 scopus 로고    scopus 로고
    • Synthesis and pharmacological evaluations of N-(substituted benzoylamino)-5-carbethoxymethyl-1,2,3,6-tetrahydropyridines as potential antiinflammatory agents
    • Yoon, K.; Wilson, T.; Williams, S.; Redda, K. Synthesis and pharmacological evaluations of N-(substituted benzoylamino)-5-carbethoxymethyl- 1,2,3,6-tetrahydropyridines as potential antiinflammatory agents, Drugs Under Experimental and Clinical Research, 2000, 26, 73-82.
    • (2000) Drugs under Experimental and Clinical Research , vol.26 , pp. 73-82
    • Yoon, K.1    Wilson, T.2    Williams, S.3    Redda, K.4
  • 21
    • 0001164365 scopus 로고
    • Synthesis of some N-(Phenylsulfonylamino)-1,2,3,6-tetrahydropyridines as Potential Anti-inflammatory Agents
    • Choi, J.O.; Wilson, T.L.; Ly, A.M.; Okoro, C.O.; Onubogo, U.C.; Redda K.K. Synthesis of some N-(Phenylsulfonylamino)-1,2,3,6-tetrahydropyridines as Potential Anti-inflammatory Agents. Med. Chem. Res., 1995, 5, 281.
    • (1995) Med. Chem. Res. , vol.5 , pp. 281
    • Choi, J.O.1    Wilson, T.L.2    Ly, A.M.3    Okoro, C.O.4    Onubogo, U.C.5    Redda, K.K.6
  • 22
    • 67249094291 scopus 로고
    • Carrageenan-Induced Edema in Hind Paw of Rats as an Assay for Anti-inflammatory Drugs
    • Winter, C.A.; Risley, E.A.; Nuss, G.W. Carrageenan-Induced Edema in Hind Paw of Rats as an Assay for Anti-inflammatory Drugs. Proc. Soc. Exp. Biol. Med. III, 1962, 544.
    • (1962) Proc. Soc. Exp. Biol. Med. III , pp. 544
    • Winter, C.A.1    Risley, E.A.2    Nuss, G.W.3


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